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An industry perspective: A streamlined screening strategy using alternative models for chemical assessment of developmental neurotoxicity

Neurotoxicology (Park Forest South), 2019-07, Vol.73, p.17-30

2019

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Investigation of potential early key events and mode of action for 1,2‐dichloroethane‐induced mammary tumors in female rats

Journal of applied toxicology, 2021-03, Vol.41 (3), p.362-374

2021

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Genetic instability of in vitro cell lines: Implications for genetic toxicity testing

Environmental and molecular mutagenesis, 2019-07, Vol.60 (6), p.559-562

2019

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Minimum datasets to establish a CAR-mediated mode of action for rodent liver tumors

Regulatory toxicology and pharmacology, 2018-07, Vol.96, p.106-120

2018

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Stat5 promotes homotypic adhesion and inhibits invasive characteristics of human breast cancer cells

Oncogene, 2005-01, Vol.24 (5), p.746-760

2005

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Bridging Sex-Specific Differences in the CAR-Mediated Hepatocarcinogenesis of Nitrapyrin Using Molecular and Apical Endpoints

Frontiers in toxicology, 2021-10, Vol.3, p.766196-766196

2021

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Mode of action and human relevance of pronamide-induced rat thyroid tumors

Regulatory toxicology and pharmacology, 2015-04, Vol.71 (3), p.541-551

2015

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Assessment of possible carcinogenicity of oxyfluorfen to humans using mode of action analysis of rodent liver effects

Toxicological sciences, 2012-08, Vol.128 (2), p.334-345

2012

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An integrated assessment of the 1,4-dioxane cancer mode of action and threshold response in rodents

Regulatory toxicology and pharmacology, 2023-08, Vol.142, p.105428-105428, Article 105428

2023

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Insensitivity of Human Prolactin Receptors to Nonhuman Prolactins: Relevance for Experimental Modeling of Prolactin Receptor-Expressing Human Cells

Endocrinology (Philadelphia), 2009-04, Vol.150 (4), p.1782-1790

2009

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Inhibition of Transcription Factor Stat5 Induces Cell Death of Human Prostate Cancer Cells

The Journal of biological chemistry, 2003-07, Vol.278 (29), p.27287-27292

2003

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Assessment of cellular and molecular metrics for dose selection in an in vivo comet assay: A case study with MDI

Environmental and molecular mutagenesis, 2021-10, Vol.62 (8), p.446-457

2021

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Integration of novel approaches demonstrates simultaneous metabolic inactivation and CAR-mediated hepatocarcinogenesis of a nitrification inhibitor

Toxicology reports, 2017-01, Vol.4, p.586-597

2017

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In vivo genotoxicity testing strategies: Report from the 8th International Workshop on Genotoxicity Testing (IWGT)

Environmental and molecular mutagenesis, 2023-12, p.1-59

2023

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STAT5 regulation of BCL10 parallels constitutive NFκB activation in lymphoid tumor cells

Molecular cancer, 2009-08, Vol.8 (1), p.67-67

2009

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Applying the erythrocyte Pig‐a assay concept to rat epididymal sperm for germ cell mutagenicity evaluation

Environmental and molecular mutagenesis, 2017-08, Vol.58 (7), p.485-493

2017

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Use of connectivity mapping to support read across: A deeper dive using data from 186 chemicals, 19 cell lines and 2 case studies

Toxicology (Amsterdam), 2019-07, Vol.423, p.84-94

2019

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Global regulatory requirements for mutagenicity assessment in the registration of industrial chemicals

Environmental and molecular mutagenesis, 2017-06, Vol.58 (5), p.345-353

2017

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Characterization of dermal sensitization potential for industrial or agricultural chemicals with EpiSensA

Journal of applied toxicology, 2021-06, Vol.41 (6), p.915-927

2021

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Pilot studies evaluating the nongenotoxic rodent carcinogens phenobarbital and clofibrate in the rat Pig‐a assay

Environmental and molecular mutagenesis, 2019-01, Vol.60 (1), p.42-46

2019

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Next generation testing strategy for assessment of genomic damage: A conceptual framework and considerations

Environmental and molecular mutagenesis, 2017-06, Vol.58 (5), p.264-283

2017

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Applied genetic toxicology: From principles to practice

Environmental and molecular mutagenesis, 2017-06, Vol.58 (5), p.232-234

2017

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A comparison of transgenic rodent mutation and in vivo comet assay responses for 91 chemicals

Mutation research. Genetic toxicology and environmental mutagenesis, 2019-03, Vol.839, p.21-35

2019

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Evaluation of genome-wide chromatin library of Stat5 binding sites in human breast cancer

Molecular cancer, 2005-02, Vol.4 (1), p.6-6

2005

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Dose-response analysis of epigenetic, metabolic, and apical endpoints after short-term exposure to experimental hepatotoxicants

Food and chemical toxicology, 2017-11, Vol.109 (Pt 1), p.690-702

2017

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An industry perspective: A streamlined screening strategy using alternative models for chemical assessment of developmental neurotoxicity

Investigation of potential early key events and mode of action for 1,2‐dichloroethane‐induced mammary tumors in female rats

Genetic instability of in vitro cell lines: Implications for genetic toxicity testing

Minimum datasets to establish a CAR-mediated mode of action for rodent liver tumors

Stat5 promotes homotypic adhesion and inhibits invasive characteristics of human breast cancer cells

Bridging Sex-Specific Differences in the CAR-Mediated Hepatocarcinogenesis of Nitrapyrin Using Molecular and Apical Endpoints

Mode of action and human relevance of pronamide-induced rat thyroid tumors

Assessment of possible carcinogenicity of oxyfluorfen to humans using mode of action analysis of rodent liver effects

An integrated assessment of the 1,4-dioxane cancer mode of action and threshold response in rodents

Insensitivity of Human Prolactin Receptors to Nonhuman Prolactins: Relevance for Experimental Modeling of Prolactin Receptor-Expressing Human Cells

Inhibition of Transcription Factor Stat5 Induces Cell Death of Human Prostate Cancer Cells

Assessment of cellular and molecular metrics for dose selection in an in vivo comet assay: A case study with MDI

Integration of novel approaches demonstrates simultaneous metabolic inactivation and CAR-mediated hepatocarcinogenesis of a nitrification inhibitor

In vivo genotoxicity testing strategies: Report from the 8th International Workshop on Genotoxicity Testing (IWGT)

STAT5 regulation of BCL10 parallels constitutive NFκB activation in lymphoid tumor cells

Applying the erythrocyte Pig‐a assay concept to rat epididymal sperm for germ cell mutagenicity evaluation

Use of connectivity mapping to support read across: A deeper dive using data from 186 chemicals, 19 cell lines and 2 case studies

Global regulatory requirements for mutagenicity assessment in the registration of industrial chemicals

Characterization of dermal sensitization potential for industrial or agricultural chemicals with EpiSensA

Pilot studies evaluating the nongenotoxic rodent carcinogens phenobarbital and clofibrate in the rat Pig‐a assay

Next generation testing strategy for assessment of genomic damage: A conceptual framework and considerations

Applied genetic toxicology: From principles to practice

A comparison of transgenic rodent mutation and in vivo comet assay responses for 91 chemicals

Evaluation of genome-wide chromatin library of Stat5 binding sites in human breast cancer

Dose-response analysis of epigenetic, metabolic, and apical endpoints after short-term exposure to experimental hepatotoxicants

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