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Slide into Action: Dynamic Shuttling of HIV Reverse Transcriptase on Nucleic Acid Substrates

Science (American Association for the Advancement of Science), 2008-11, Vol.322 (5904), p.1092-1097

2008

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Identification of Biologically Active, HIV TAR RNA-Binding Small Molecules Using Small Molecule Microarrays

Journal of the American Chemical Society, 2014-06, Vol.136 (23), p.8402-8410

2014

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Dihydroxyphenyl- and Heteroaromatic-Based Thienopyrimidinones to Tackle HIV-1 LEDGF/p75-Dependent IN Activity

Molecules (Basel, Switzerland), 2023-09, Vol.28 (18), p.6700

2023

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Dynamic binding orientations direct activity of HIV reverse transcriptase

Nature, 2008-05, Vol.453 (7192), p.184-189

2008

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Hydroxylated tropolones inhibit hepatitis B virus replication by blocking viral ribonuclease H activity

Antimicrobial agents and chemotherapy, 2015-02, Vol.59 (2), p.1070-1079

2015

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Selective Small-Molecule Targeting of a Triple Helix Encoded by the Long Noncoding RNA, MALAT1

ACS chemical biology, 2019-02, Vol.14 (2), p.223-235

2019

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Autophagy Deregulation in HIV-1-Infected Cells Increases Extracellular Vesicle Release and Contributes to TLR3 Activation

Viruses, 2024-04, Vol.16 (4), p.643

2024

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HIV-1 Transcription Inhibition Using Small RNA-Binding Molecules

Pharmaceuticals (Basel, Switzerland), 2023-12, Vol.17 (1), p.33

2023

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Ribonuclease H/DNA Polymerase HIV-1 Reverse Transcriptase Dual Inhibitor: Mechanistic Studies on the Allosteric Mode of Action of Isatin-Based Compound RMNC6

PloS one, 2016-01, Vol.11 (1), p.e0147225

2016

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Two distinct modes of metal ion binding in the nuclease active site of a viral DNA-packaging terminase: insight into the two-metal-ion catalytic mechanism

Nucleic acids research, 2015-12, Vol.43 (22), p.11003-11016

2015

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Interplay of primary sequence, position and secondary RNA structure determines alternative splicing of LMNA in a pre-mature aging syndrome

Nucleic acids research, 2019-06, Vol.47 (11), p.5922-5935

2019

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3,7-Dihydroxytropolones Inhibit Initiation of Hepatitis B Virus Minus-Strand DNA Synthesis

Molecules (Basel, Switzerland), 2020-09, Vol.25 (19), p.4434

2020

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Structural Fluidity of the Human Immunodeficiency Virus Rev Response Element

Viruses, 2020-01, Vol.12 (1), p.86

2020

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A small stem-loop structure of the Ebola virus trailer is essential for replication and interacts with heat-shock protein A8

Nucleic acids research, 2016-09, Vol.44 (20), p.9831

2016

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Sensitivity of the C-Terminal Nuclease Domain of Kaposi's Sarcoma-Associated Herpesvirus ORF29 to Two Classes of Active-Site Ligands

Antimicrobial agents and chemotherapy, 2018-10, Vol.62 (10)

2018

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Interaction between Reverse Transcriptase and Integrase Is Required for Reverse Transcription during HIV-1 Replication

Journal of virology, 2015-12, Vol.89 (23), p.12058-12069

2015

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Characterizing and circumventing sequence restrictions for synthesis of circular RNA in vitro

Nucleic acids research, 2021-04, Vol.49 (6), p.e35-e35

2021

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Scaffold hopping and optimisation of 3',4'-dihydroxyphenyl- containing thienopyrimidinones: synthesis of quinazolinone derivatives as novel allosteric inhibitors of HIV-1 reverse transcriptase-associated ribonuclease H

Journal of enzyme inhibition and medicinal chemistry, 2020-01, Vol.35 (1), p.1953-1963

2020

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Intrinsic DNA synthesis fidelity of xenotropic murine leukemia virus‐related virus reverse transcriptase

The FEBS journal, 2012-04, Vol.279 (8), p.1433-1444

2012

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HIV Genetic Diversity – Superpower of a Formidable Virus

Current HIV research, 2020-01, Vol.18 (2), p.69-73

2020

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Development of Small Molecules with a Noncanonical Binding Mode to HIV‑1 Trans Activation Response (TAR) RNA

Journal of medicinal chemistry, 2016-12, Vol.59 (24), p.11148-11160

2016

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Multiple sources of contamination in samples from patients reported to have XMRV infection

PloS one, 2012-02, Vol.7 (2), p.e30889-e30889

2012

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Structure-Activity Analysis of Vinylogous Urea Inhibitors of Human Immunodeficiency Virus-Encoded Ribonuclease H

Antimicrobial Agents and Chemotherapy, 2010-09, Vol.54 (9), p.3913-3921

2010

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The HIV-1 Rev response element (RRE) adopts alternative conformations that promote different rates of virus replication

Nucleic acids research, 2015-05, Vol.43 (9), p.4676-4686

2015

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Dissecting APOBEC3G Substrate Specificity by Nucleoside Analog Interference

The Journal of biological chemistry, 2009-03, Vol.284 (11), p.7047-7058

2009

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Slide into Action: Dynamic Shuttling of HIV Reverse Transcriptase on Nucleic Acid Substrates

Identification of Biologically Active, HIV TAR RNA-Binding Small Molecules Using Small Molecule Microarrays

Dihydroxyphenyl- and Heteroaromatic-Based Thienopyrimidinones to Tackle HIV-1 LEDGF/p75-Dependent IN Activity

Dynamic binding orientations direct activity of HIV reverse transcriptase

Hydroxylated tropolones inhibit hepatitis B virus replication by blocking viral ribonuclease H activity

Selective Small-Molecule Targeting of a Triple Helix Encoded by the Long Noncoding RNA, MALAT1

Autophagy Deregulation in HIV-1-Infected Cells Increases Extracellular Vesicle Release and Contributes to TLR3 Activation

HIV-1 Transcription Inhibition Using Small RNA-Binding Molecules

Ribonuclease H/DNA Polymerase HIV-1 Reverse Transcriptase Dual Inhibitor: Mechanistic Studies on the Allosteric Mode of Action of Isatin-Based Compound RMNC6

Two distinct modes of metal ion binding in the nuclease active site of a viral DNA-packaging terminase: insight into the two-metal-ion catalytic mechanism

Interplay of primary sequence, position and secondary RNA structure determines alternative splicing of LMNA in a pre-mature aging syndrome

3,7-Dihydroxytropolones Inhibit Initiation of Hepatitis B Virus Minus-Strand DNA Synthesis

Structural Fluidity of the Human Immunodeficiency Virus Rev Response Element

A small stem-loop structure of the Ebola virus trailer is essential for replication and interacts with heat-shock protein A8

Sensitivity of the C-Terminal Nuclease Domain of Kaposi's Sarcoma-Associated Herpesvirus ORF29 to Two Classes of Active-Site Ligands

Interaction between Reverse Transcriptase and Integrase Is Required for Reverse Transcription during HIV-1 Replication

Characterizing and circumventing sequence restrictions for synthesis of circular RNA in vitro

Scaffold hopping and optimisation of 3',4'-dihydroxyphenyl- containing thienopyrimidinones: synthesis of quinazolinone derivatives as novel allosteric inhibitors of HIV-1 reverse transcriptase-associated ribonuclease H

Intrinsic DNA synthesis fidelity of xenotropic murine leukemia virus‐related virus reverse transcriptase

HIV Genetic Diversity – Superpower of a Formidable Virus

Development of Small Molecules with a Noncanonical Binding Mode to HIV‑1 Trans Activation Response (TAR) RNA

Multiple sources of contamination in samples from patients reported to have XMRV infection

Structure-Activity Analysis of Vinylogous Urea Inhibitors of Human Immunodeficiency Virus-Encoded Ribonuclease H

The HIV-1 Rev response element (RRE) adopts alternative conformations that promote different rates of virus replication

Dissecting APOBEC3G Substrate Specificity by Nucleoside Analog Interference

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