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X-ray structure of a carpet-like antimicrobial defensin-phospholipid membrane disruption complex

Nature communications, 2018-05, Vol.9 (1), p.1962-10, Article 1962

2018

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The Plant Defensin, NaD1, Enters the Cytoplasm of Fusarium Oxysporum Hyphae

The Journal of biological chemistry, 2008-05, Vol.283 (21), p.14445-14452

2008

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Crocodile defensin (CpoBD13) antifungal activity via pH-dependent phospholipid targeting and membrane disruption

Nature communications, 2023-03, Vol.14 (1), p.1170-1170, Article 1170

2023

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The Tomato Defensin TPP3 Binds Phosphatidylinositol (4,5)-Bisphosphate via a Conserved Dimeric Cationic Grip Conformation To Mediate Cell Lysis

Molecular and cellular biology, 2015-06, Vol.35 (11), p.1964-1978

2015

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Phosphoinositide-mediated oligomerization of a defensin induces cell lysis

eLife, 2014-04, Vol.3, p.e01808

2014

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Binding of phosphatidic acid by NsD7 mediates the formation of helical defensin–lipid oligomeric assemblies and membrane permeabilization

Proceedings of the National Academy of Sciences - PNAS, 2016-10, Vol.113 (40), p.11202-11207

2016

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Salt-Tolerant Antifungal and Antibacterial Activities of the Corn Defensin ZmD32

Frontiers in microbiology, 2019-04, Vol.10, p.795-795

2019

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Plexin B2 Is a Regulator of Monocyte Apoptotic Cell Disassembly

Cell reports (Cambridge), 2019-11, Vol.29 (7), p.1821-1831.e3

2019

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Human β-Defensin 2 (HBD-2) Displays Oncolytic Activity but Does Not Affect Tumour Cell Migration

Biomolecules (Basel, Switzerland), 2022-02, Vol.12 (2), p.264

2022

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Isolation and Properties of Floral Defensins from Ornamental Tobacco and Petunia

Plant physiology (Bethesda), 2003-03, Vol.131 (3), p.1283-1293

2003

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Tumor cell membrane-targeting cationic antimicrobial peptides: novel insights into mechanisms of action and therapeutic prospects

Cellular and molecular life sciences : CMLS, 2017-10, Vol.74 (20), p.3809-3825

2017

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The Defensins Consist of Two Independent, Convergent Protein Superfamilies

Molecular biology and evolution, 2016-09, Vol.33 (9), p.2345-2356

2016

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Convergent evolution of defensin sequence, structure and function

Cellular and molecular life sciences : CMLS, 2017-02, Vol.74 (4), p.663-682

2017

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Defensin-lipid interactions in membrane targeting: mechanisms of action and opportunities for the development of antimicrobial and anticancer therapeutics

Biochemical Society transactions, 2022-02, Vol.50 (1), p.423

2022

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The Three-dimensional Solution Structure of NaD1, a New Floral Defensin from Nicotiana alata and its Application to a Homology Model of the Crop Defense Protein alfAFP

Journal of molecular biology, 2003-01, Vol.325 (1), p.175-188

2003

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Structure of the defensin NsD7 in complex with PIP2 reveals that defensin : lipid oligomer topologies are dependent on lipid type

FEBS letters, 2017-08, Vol.591 (16), p.2482-2490

2017

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Phosphoinositides: multipurpose cellular lipids with emerging roles in cell death

Cell death and differentiation, 2019-05, Vol.26 (5), p.781-793

2019

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Structural and functional characterization of the membrane‐permeabilizing activity of Nicotiana occidentalis defensin NoD173 and protein engineering to enhance oncolysis

The FASEB journal, 2019-05, Vol.33 (5), p.6470-6482

2019

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Structure of the defensin NsD7 in complex with PIP 2 reveals that defensin : lipid oligomer topologies are dependent on lipid type

FEBS letters, 2017-08, Vol.591 (16), p.2482-2490

2017

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Importance of phosphoinositide binding by human β‐defensin 3 for Akt‐dependent cytokine induction

Immunology and cell biology, 2018-01, Vol.96 (1), p.54-67

2018

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Human β-defensin 2 kills Candida albicans through phosphatidylinositol 4,5-bisphosphate-mediated membrane permeabilization

Science advances, 2018-07, Vol.4 (7), p.eaat0979-eaat0979

2018

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Human β-defensin 3 contains an oncolytic motif that binds PI(4,5)P2 to mediate tumour cell permeabilisation

Oncotarget, 2016-01, Vol.7 (2), p.2054-2069

2016

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Pollen-Specific RALF from Tomato That Regulates Pollen Tube Elongation

Plant physiology (Bethesda), 2010-06, Vol.153 (2), p.703-715

2010

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Dimerization of Plant Defensin NaD1 Enhances Its Antifungal Activity

The Journal of biological chemistry, 2012-06, Vol.287 (24), p.19961-19972

2012

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Novel insights on the mechanism of action of α-amylase inhibitors from the plant defensin family

Proteins, structure, function, and bioinformatics, 2008-11, Vol.73 (3), p.719-729

2008

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X-ray structure of a carpet-like antimicrobial defensin-phospholipid membrane disruption complex

The Plant Defensin, NaD1, Enters the Cytoplasm of Fusarium Oxysporum Hyphae

Crocodile defensin (CpoBD13) antifungal activity via pH-dependent phospholipid targeting and membrane disruption

The Tomato Defensin TPP3 Binds Phosphatidylinositol (4,5)-Bisphosphate via a Conserved Dimeric Cationic Grip Conformation To Mediate Cell Lysis

Phosphoinositide-mediated oligomerization of a defensin induces cell lysis

Binding of phosphatidic acid by NsD7 mediates the formation of helical defensin–lipid oligomeric assemblies and membrane permeabilization

Salt-Tolerant Antifungal and Antibacterial Activities of the Corn Defensin ZmD32

Plexin B2 Is a Regulator of Monocyte Apoptotic Cell Disassembly

Human β-Defensin 2 (HBD-2) Displays Oncolytic Activity but Does Not Affect Tumour Cell Migration

Isolation and Properties of Floral Defensins from Ornamental Tobacco and Petunia

Tumor cell membrane-targeting cationic antimicrobial peptides: novel insights into mechanisms of action and therapeutic prospects

The Defensins Consist of Two Independent, Convergent Protein Superfamilies

Convergent evolution of defensin sequence, structure and function

Defensin-lipid interactions in membrane targeting: mechanisms of action and opportunities for the development of antimicrobial and anticancer therapeutics

The Three-dimensional Solution Structure of NaD1, a New Floral Defensin from Nicotiana alata and its Application to a Homology Model of the Crop Defense Protein alfAFP

Structure of the defensin NsD7 in complex with PIP2 reveals that defensin : lipid oligomer topologies are dependent on lipid type

Phosphoinositides: multipurpose cellular lipids with emerging roles in cell death

Structural and functional characterization of the membrane‐permeabilizing activity of Nicotiana occidentalis defensin NoD173 and protein engineering to enhance oncolysis

Structure of the defensin NsD7 in complex with PIP 2 reveals that defensin : lipid oligomer topologies are dependent on lipid type

Importance of phosphoinositide binding by human β‐defensin 3 for Akt‐dependent cytokine induction

Human β-defensin 2 kills Candida albicans through phosphatidylinositol 4,5-bisphosphate-mediated membrane permeabilization

Human β-defensin 3 contains an oncolytic motif that binds PI(4,5)P2 to mediate tumour cell permeabilisation

Pollen-Specific RALF from Tomato That Regulates Pollen Tube Elongation

Dimerization of Plant Defensin NaD1 Enhances Its Antifungal Activity

Novel insights on the mechanism of action of α-amylase inhibitors from the plant defensin family

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