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Early existence and biochemical evolution characterise acutely synaptotoxic PrPSc

PLoS pathogens, 2019-04, Vol.15 (4), p.e1007712

2019

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Misfolded α-synuclein causes hyperactive respiration without functional deficit in live neuroblastoma cells

Disease models & mechanisms, 2020-01, Vol.13 (1)

2020

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Phenolic compounds disrupt spike-mediated receptor-binding and entry of SARS-CoV-2 pseudo-virions

PloS one, 2021-06, Vol.16 (6), p.e0253489-e0253489

2021

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Prion Infection Impairs Cholesterol Metabolism in Neuronal Cells

The Journal of biological chemistry, 2014-01, Vol.289 (2), p.789-802

2014

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Markers of A1 astrocytes stratify to molecular sub-types in sporadic Creutzfeldt–Jakob disease brain

Brain communications, 2020-01, Vol.2 (2), p.fcaa029-fcaa029

2020

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Pathogenic Mutations within the Hydrophobic Domain of the Prion Protein Lead to the Formation of Protease-Sensitive Prion Species with Increased Lethality

Journal of Virology, 2014-03, Vol.88 (5), p.2690-2703

2014

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Epithelial cell size dysregulation in human lung adenocarcinoma

PloS one, 2022-10, Vol.17 (10), p.e0274091-e0274091

2022

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The PINK1/Parkin pathway of mitophagy exerts a protective effect during prion disease

PloS one, 2024-02, Vol.19 (2), p.e0298095-e0298095

2024

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Distribution of microRNA profiles in pre-clinical and clinical forms of murine and human prion disease

Communications biology, 2021-03, Vol.4 (1), p.411-411, Article 411

2021

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The role of lipids in α-synuclein misfolding and neurotoxicity

The Journal of biological chemistry, 2019-06, Vol.294 (23), p.9016-9028

2019

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Prion‐infected cells regulate the release of exosomes with distinct ultrastructural features

The FASEB journal, 2012-10, Vol.26 (10), p.4160-4173

2012

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Glycosaminoglycan sulphation affects the seeded misfolding of a mutant prion protein

PloS one, 2010-08, Vol.5 (8), p.e12351-e12351

2010

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Pathogenic mechanisms of prion protein, amyloid‐β and α‐synuclein misfolding: the prion concept and neurotoxicity of protein oligomers

Journal of neurochemistry, 2016-10, Vol.139 (2), p.162-180

2016

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Dominant roles of the polybasic proline motif and copper in the PrP23-89-mediated stress protection response

Journal of cell science, 2009-05, Vol.122 (10), p.1518-1528

2009

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Conservation of a Glycine-rich Region in the Prion Protein Is Required for Uptake of Prion Infectivity

The Journal of biological chemistry, 2010-06, Vol.285 (26), p.20213-20223

2010

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Prion protein glycosylation

Journal of neurochemistry, 2005-05, Vol.93 (4), p.793-801

2005

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Residues Surrounding the Glycosylphosphatidylinositol Anchor Attachment Site of PrP Modulate Prion Infection: Insight from the Resistance of Rabbits to Prion Disease

Journal of Virology, 2010-07, Vol.84 (13), p.6678-6686

2010

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Prion pathogenesis in the absence of NLRP3/ASC inflammasomes

PloS one, 2015-02, Vol.10 (2), p.e0117208-e0117208

2015

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Preparation and Immunostaining of the Myenteric Plexus of Prion-Infected Mice

Methods in molecular biology (Clifton, N.J.), 2017, Vol.1658, p.285

2017

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Anti-prion activity of a panel of aromatic chemical compounds: in vitro and in silico approaches

PloS one, 2014-01, Vol.9 (1), p.e84531

2014

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Morphine Withdrawal Modifies Prion Protein Expression in Rat Hippocampus

PloS one, 2017-01, Vol.12 (1), p.e0169571

2017

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Flexible N-terminal Region of Prion Protein Influences Conformation of Protease-resistant Prion Protein Isoforms Associated with Cross-species Scrapie Infection in Vivo and in Vitro

The Journal of biological chemistry, 2004-04, Vol.279 (14), p.13689-13695

2004

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In Vivo-Near Infrared Imaging of Neurodegeneration

Methods in molecular biology (Clifton, N.J.), 2017, Vol.1658, p.253

2017

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Prion subcellular fractionation reveals infectivity spectrum, with a high titre-low PrPres level disparity

Molecular neurodegeneration, 2012-04, Vol.7 (1), p.18-18

2012

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RT-QuIC Assays for Prion Disease Detection and Diagnostics

Methods in molecular biology (Clifton, N.J.), 2017-01, Vol.1658, p.185

2017

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Early existence and biochemical evolution characterise acutely synaptotoxic PrPSc

Misfolded α-synuclein causes hyperactive respiration without functional deficit in live neuroblastoma cells

Phenolic compounds disrupt spike-mediated receptor-binding and entry of SARS-CoV-2 pseudo-virions

Prion Infection Impairs Cholesterol Metabolism in Neuronal Cells

Markers of A1 astrocytes stratify to molecular sub-types in sporadic Creutzfeldt–Jakob disease brain

Pathogenic Mutations within the Hydrophobic Domain of the Prion Protein Lead to the Formation of Protease-Sensitive Prion Species with Increased Lethality

Epithelial cell size dysregulation in human lung adenocarcinoma

The PINK1/Parkin pathway of mitophagy exerts a protective effect during prion disease

Distribution of microRNA profiles in pre-clinical and clinical forms of murine and human prion disease

The role of lipids in α-synuclein misfolding and neurotoxicity

Prion‐infected cells regulate the release of exosomes with distinct ultrastructural features

Glycosaminoglycan sulphation affects the seeded misfolding of a mutant prion protein

Pathogenic mechanisms of prion protein, amyloid‐β and α‐synuclein misfolding: the prion concept and neurotoxicity of protein oligomers

Dominant roles of the polybasic proline motif and copper in the PrP23-89-mediated stress protection response

Conservation of a Glycine-rich Region in the Prion Protein Is Required for Uptake of Prion Infectivity

Prion protein glycosylation

Residues Surrounding the Glycosylphosphatidylinositol Anchor Attachment Site of PrP Modulate Prion Infection: Insight from the Resistance of Rabbits to Prion Disease

Prion pathogenesis in the absence of NLRP3/ASC inflammasomes

Preparation and Immunostaining of the Myenteric Plexus of Prion-Infected Mice

Anti-prion activity of a panel of aromatic chemical compounds: in vitro and in silico approaches

Morphine Withdrawal Modifies Prion Protein Expression in Rat Hippocampus

Flexible N-terminal Region of Prion Protein Influences Conformation of Protease-resistant Prion Protein Isoforms Associated with Cross-species Scrapie Infection in Vivo and in Vitro

In Vivo-Near Infrared Imaging of Neurodegeneration

Prion subcellular fractionation reveals infectivity spectrum, with a high titre-low PrPres level disparity

RT-QuIC Assays for Prion Disease Detection and Diagnostics

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