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Nonpeptide Urotensin-II Receptor Antagonists: A New Ligand Class Based on Piperazino-Phthalimide and Piperazino-Isoindolinone Subunits

Journal of medicinal chemistry, 2009-12, Vol.52 (23), p.7432-7445

2009

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Binary Targeting of siRNA to Hematologic Cancer Cells In Vivo Using Layer‐by‐Layer Nanoparticles

Advanced functional materials, 2019-05, Vol.29 (20), p.n/a

2019

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Mild Intramolecular Ring Opening of Oxetanes

Organic letters, 2019-12, Vol.21 (23), p.9642-9645

2019

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Tandem Suzuki Coupling/Intramolecular Oxetane Ring Opening to Form Polycyclic Ring Systems

Organic letters, 2020-08, Vol.22 (15), p.5828-5832

2020

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On the Nature of the Catalytic Palladium-Mediated Elimination of Allylic Carbonates and Acetates To Form 1,3-Dienes

Journal of the American Chemical Society, 1997-06, Vol.119 (25), p.5956-5957

1997

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Selection of a 2-azabicyclo[2.2.2]octane-based α4β1 integrin antagonist as an inhaled anti-asthmatic agent

Bioorganic & medicinal chemistry, 2006-06, Vol.14 (12), p.4208-4216

2006

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Generation of novel, potent urotensin-II receptor antagonists by alkylation–cyclization of isoindolinone C3-carbanions

Tetrahedron letters, 2009-09, Vol.50 (35), p.4958-4961

2009

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Phenylpiperidine-benzoxazinones as urotensin-II receptor antagonists: Synthesis, SAR, and in vivo assessment

Bioorganic & medicinal chemistry, 2007-12, Vol.17 (23), p.6489-6492

2007

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1,2,4-Triazolo[3,4- a]pyridine as a novel, constrained template for fibrinogen receptor (GPIIb/IIIa) antagonists

Bioorganic & medicinal chemistry letters, 2001-10, Vol.11 (19), p.2619-2622

2001

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Convenient preparation of aryl-substituted nortropanes by SuzukiMiyaura methodology

Canadian journal of chemistry, 2006-04, Vol.84 (4), p.555-560

2006

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Enantioselective Diels-Alder reactions: room temperature bis(oxazoline)-zinc, -magnesium, and -copper triflate catalysts

Tetrahedron: asymmetry, 1997-09, Vol.8 (18), p.3073-3078

1997

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The Heck reaction with unprotected allylic amidines and guanidines

Tetrahedron letters, 2002-03, Vol.43 (11), p.1951-1953

2002

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Abstract DDT02-04: A novel PRMT5 inhibitor with potent in vitro and in vivo activity in preclinical lung cancer models

Cancer research (Chicago, Ill.), 2017-07, Vol.77 (13_Supplement), p.DDT02-04-DDT02-04

2017

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Stereocontrol between Remote Atom Centers in Acyclic Substrates. Anti Addition of Hydride to 1,5-, 1,6-, and 1,7-Hydroxy Ketones

Journal of organic chemistry, 1998-10, Vol.63 (22), p.7964-7981

1998

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Catalytic Rhodium-Mediated Tetraene Carbocyclizations

Organometallics, 1994-12, Vol.13 (12), p.4787-4793

1994

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Tetrazole‐Based Angiotensin II Type 1 (AT1) Antagonists for the Treatment of Heart Failure and Congestive Hypertension

Bioactive Heterocyclic Compound Classes, 2012, p.153-167

2012

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Synthesis of triazolopyridines as conformationally constrained tertiary amides

Tetrahedron letters, 2000-06, Vol.41 (23), p.4533-4536

2000

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Selection of a 2-azabicyclo[2.2.2]octane-based alpha4beta1 integrin antagonist as an inhaled anti-asthmatic agent

Bioorganic & medicinal chemistry, 2006-06, Vol.14 (12), p.4208-4216

2006

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Selection of a 2-azabicyclo[2.2.2]octane-based alpha sub(4) beta sub(1) integrin antagonist as an inhaled anti-asthmatic agent

Bioorganic & medicinal chemistry, 2006-06, Vol.14 (12), p.4208-4216

2006

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Selection of a 2-azabicyclo[2.2.2]octane-based α 4β 1 integrin antagonist as an inhaled anti-asthmatic agent

Bioorganic & medicinal chemistry, 2006, Vol.14 (12), p.4208-4216

2006

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Synthesis and Biological Evaluation of 1,2,4-Triazolo[2,3-a]pyrrole Derivatives as Alpha-4 ( α4) Integrin Antagonists

Letters in drug design & discovery, 2005-12, Vol.2 (8), p.601-605

2005

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Remote stereocontrol in acyclic systems. Hydride addition to 1,5- and 1,6-hydroxy ketones mediated by metal chelation

Tetrahedron letters, 1999-01, Vol.40 (4), p.593-596

1999

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ChemInform Abstract: Synthesis of Triazolopyridines as Conformationally Constrained Tertiary Amides

ChemInform, 2000-09, Vol.31 (36), p.no-no

2000

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ChemInform Abstract: The Heck Reaction with Unprotected Allylic Amidines and Guanidines

ChemInform, 2002-07, Vol.33 (26), p.no-no

2002

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ChemInform Abstract: Remote Stereocontrol in Acyclic Systems. Hydride Addition to 1,5- and 1,6-Hydroxy Ketones Mediated by Metal Chelation

ChemInform, 1999-04, Vol.30 (15), p.no-no

1999

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Nonpeptide Urotensin-II Receptor Antagonists: A New Ligand Class Based on Piperazino-Phthalimide and Piperazino-Isoindolinone Subunits

Binary Targeting of siRNA to Hematologic Cancer Cells In Vivo Using Layer‐by‐Layer Nanoparticles

Mild Intramolecular Ring Opening of Oxetanes

Tandem Suzuki Coupling/Intramolecular Oxetane Ring Opening to Form Polycyclic Ring Systems

On the Nature of the Catalytic Palladium-Mediated Elimination of Allylic Carbonates and Acetates To Form 1,3-Dienes

Selection of a 2-azabicyclo[2.2.2]octane-based α4β1 integrin antagonist as an inhaled anti-asthmatic agent

Generation of novel, potent urotensin-II receptor antagonists by alkylation–cyclization of isoindolinone C3-carbanions

Phenylpiperidine-benzoxazinones as urotensin-II receptor antagonists: Synthesis, SAR, and in vivo assessment

1,2,4-Triazolo[3,4- a]pyridine as a novel, constrained template for fibrinogen receptor (GPIIb/IIIa) antagonists

Convenient preparation of aryl-substituted nortropanes by SuzukiMiyaura methodology

Enantioselective Diels-Alder reactions: room temperature bis(oxazoline)-zinc, -magnesium, and -copper triflate catalysts

The Heck reaction with unprotected allylic amidines and guanidines

Abstract DDT02-04: A novel PRMT5 inhibitor with potent in vitro and in vivo activity in preclinical lung cancer models

Stereocontrol between Remote Atom Centers in Acyclic Substrates. Anti Addition of Hydride to 1,5-, 1,6-, and 1,7-Hydroxy Ketones

Catalytic Rhodium-Mediated Tetraene Carbocyclizations

Tetrazole‐Based Angiotensin II Type 1 (AT1) Antagonists for the Treatment of Heart Failure and Congestive Hypertension

Synthesis of triazolopyridines as conformationally constrained tertiary amides

Selection of a 2-azabicyclo[2.2.2]octane-based alpha4beta1 integrin antagonist as an inhaled anti-asthmatic agent

Selection of a 2-azabicyclo[2.2.2]octane-based alpha sub(4) beta sub(1) integrin antagonist as an inhaled anti-asthmatic agent

Selection of a 2-azabicyclo[2.2.2]octane-based α 4β 1 integrin antagonist as an inhaled anti-asthmatic agent

Synthesis and Biological Evaluation of 1,2,4-Triazolo[2,3-a]pyrrole Derivatives as Alpha-4 ( α4) Integrin Antagonists

Remote stereocontrol in acyclic systems. Hydride addition to 1,5- and 1,6-hydroxy ketones mediated by metal chelation

ChemInform Abstract: Synthesis of Triazolopyridines as Conformationally Constrained Tertiary Amides

ChemInform Abstract: The Heck Reaction with Unprotected Allylic Amidines and Guanidines

ChemInform Abstract: Remote Stereocontrol in Acyclic Systems. Hydride Addition to 1,5- and 1,6-Hydroxy Ketones Mediated by Metal Chelation

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