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Evaluating Chemicals for Thyroid Disruption: Opportunities and Challenges with in Vitro Testing and Adverse Outcome Pathway Approaches

Environmental health perspectives, 2019-09, Vol.127 (9), p.95001

2019

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High-throughput screening and chemotype-enrichment analysis of ToxCast phase II chemicals evaluated for human sodium-iodide symporter (NIS) inhibition

Environment international, 2019-05, Vol.126 (C), p.377-386

2019

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High-Throughput Screening and Quantitative Chemical Ranking for Sodium-Iodide Symporter Inhibitors in ToxCast Phase I Chemical Library

Environmental science & technology, 2018-05, Vol.52 (9), p.5417-5426

2018

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Evaluation of potential sodium-iodide symporter (NIS) inhibitors using a secondary Fischer rat thyroid follicular cell (FRTL-5) radioactive iodide uptake (RAIU) assay

Archives of toxicology, 2020-03, Vol.94 (3), p.873-885

2020

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Development of a screening approach to detect thyroid disrupting chemicals that inhibit the human sodium iodide symporter (NIS)

Toxicology in vitro, 2017-04, Vol.40, p.66-78

2017

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The use of purified rat Leydig cells complements the H295R screen to detect chemical-induced alterations in testosterone production

Biology of reproduction, 2018-02, Vol.98 (2), p.239-249

2018

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Expanded high-throughput screening and chemotype-enrichment analysis of the phase II: e1k ToxCast library for human sodium-iodide symporter (NIS) inhibition

Archives of toxicology, 2021-05, Vol.95 (5), p.1723-1737

2021

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Characterization of the Hypothalamic-Pituitary-Adrenal Axis Response to Atrazine and Metabolites in the Female Rat

Toxicological sciences, 2009-11, Vol.112 (1), p.88-99

2009

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Chlorotriazine Herbicides and Metabolites Activate an ACTH-dependent Release of Corticosterone in Male Wistar Rats

Toxicological sciences, 2009-11, Vol.112 (1), p.78-87

2009

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Atrazine and reproductive function: mode and mechanism of action studies

Birth defects research. Part B. Developmental and reproductive toxicology, 2007-04, Vol.80 (2), p.98-112

2007

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Modulation of aromatase activity as a mode of action for endocrine disrupting chemicals in a marine fish

Aquatic toxicology, 2014-02, Vol.147, p.140-150

2014

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Assessment of DE-71, a Commercial Polybrominated Diphenyl Ether (PBDE) Mixture, in the EDSP Male and Female Pubertal Protocols

Toxicological sciences, 2004-03, Vol.78 (1), p.144-155

2004

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Measurement of steroids in rats after exposure to an endocrine disruptor: Mass spectrometry and radioimmunoassay demonstrate similar results

Journal of pharmacological and toxicological methods, 2013-11, Vol.68 (3), p.314-322

2013

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Understanding the effects of atrazine on steroidogenesis in rat granulosa and H295R adrenal cortical carcinoma cells

Reproductive toxicology (Elmsford, N.Y.), 2011-02, Vol.31 (2), p.184-193

2011

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In vitro metabolism and bioavailability tests for endocrine active substances: what is needed next for regulatory purposes?

ALTEX, alternatives to animal experimentation, 2013, Vol.30 (3), p.331-351

2013

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Novel molecular events associated with altered steroidogenesis induced by exposure to atrazine in the intact and castrate male rat

Reproductive toxicology (Elmsford, N.Y.), 2014-08, Vol.47, p.59-69

2014

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Approaches for predicting effects of unintended environmental exposure to an endocrine active pharmaceutical, tamoxifen

Environmental toxicology, 2016-12, Vol.31 (12), p.1834-1850

2016

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Atrazine does not induce pica behavior at doses that increase hypothalamic–pituitary–adrenal axis activation and cause conditioned taste avoidance

Neurotoxicology and teratology, 2012-05, Vol.34 (3), p.295-302

2012

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The Impact of Gender and Estrogen on Striatal Dopaminergic Neurotoxicity

Annals of the New York Academy of Sciences, 1998-05, Vol.844 (1), p.153-165

1998

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Persistent DDT metabolite p,p'-DDE is a potent androgen receptor antagonist

Nature (London), 1995-06, Vol.375 (6532), p.581-585

1995

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Nature of the Binding Interaction for 50 Structurally Diverse Chemicals with Rat Estrogen Receptors

Toxicological sciences, 2006-11, Vol.94 (1), p.46-56

2006

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Molecular Modeling for Screening Environmental Chemicals for Estrogenicity: Use of the Toxicant-Target Approach

Chemical research in toxicology, 2009-09, Vol.22 (9), p.1594-1602

2009

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Effects of Altered Food Intake during Pubertal Development in Male and Female Wistar Rats

Toxicological sciences, 2007-11, Vol.100 (1), p.194-202

2007

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Endocrine-Disrupting Chemicals: Prepubertal Exposures and Effects on Sexual Maturation and Thyroid Activity in the Female Rat. A Focus on the EDSTAC Recommendations

Critical reviews in toxicology, 2000-01, Vol.30 (2), p.135-196

2000

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Pubertal Development in Female Wistar Rats following Exposure to Propazine and Atrazine Biotransformation By-Products, Diamino-S-Chlorotriazine and Hydroxyatrazine

Toxicological sciences, 2003-11, Vol.76 (1), p.190-200

2003

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Evaluating Chemicals for Thyroid Disruption: Opportunities and Challenges with in Vitro Testing and Adverse Outcome Pathway Approaches

High-throughput screening and chemotype-enrichment analysis of ToxCast phase II chemicals evaluated for human sodium-iodide symporter (NIS) inhibition

High-Throughput Screening and Quantitative Chemical Ranking for Sodium-Iodide Symporter Inhibitors in ToxCast Phase I Chemical Library

Evaluation of potential sodium-iodide symporter (NIS) inhibitors using a secondary Fischer rat thyroid follicular cell (FRTL-5) radioactive iodide uptake (RAIU) assay

Development of a screening approach to detect thyroid disrupting chemicals that inhibit the human sodium iodide symporter (NIS)

The use of purified rat Leydig cells complements the H295R screen to detect chemical-induced alterations in testosterone production

Expanded high-throughput screening and chemotype-enrichment analysis of the phase II: e1k ToxCast library for human sodium-iodide symporter (NIS) inhibition

Characterization of the Hypothalamic-Pituitary-Adrenal Axis Response to Atrazine and Metabolites in the Female Rat

Chlorotriazine Herbicides and Metabolites Activate an ACTH-dependent Release of Corticosterone in Male Wistar Rats

Atrazine and reproductive function: mode and mechanism of action studies

Modulation of aromatase activity as a mode of action for endocrine disrupting chemicals in a marine fish

Assessment of DE-71, a Commercial Polybrominated Diphenyl Ether (PBDE) Mixture, in the EDSP Male and Female Pubertal Protocols

Measurement of steroids in rats after exposure to an endocrine disruptor: Mass spectrometry and radioimmunoassay demonstrate similar results

Understanding the effects of atrazine on steroidogenesis in rat granulosa and H295R adrenal cortical carcinoma cells

In vitro metabolism and bioavailability tests for endocrine active substances: what is needed next for regulatory purposes?

Novel molecular events associated with altered steroidogenesis induced by exposure to atrazine in the intact and castrate male rat

Approaches for predicting effects of unintended environmental exposure to an endocrine active pharmaceutical, tamoxifen

Atrazine does not induce pica behavior at doses that increase hypothalamic–pituitary–adrenal axis activation and cause conditioned taste avoidance

The Impact of Gender and Estrogen on Striatal Dopaminergic Neurotoxicity

Persistent DDT metabolite p,p'-DDE is a potent androgen receptor antagonist

Nature of the Binding Interaction for 50 Structurally Diverse Chemicals with Rat Estrogen Receptors

Molecular Modeling for Screening Environmental Chemicals for Estrogenicity: Use of the Toxicant-Target Approach

Effects of Altered Food Intake during Pubertal Development in Male and Female Wistar Rats

Endocrine-Disrupting Chemicals: Prepubertal Exposures and Effects on Sexual Maturation and Thyroid Activity in the Female Rat. A Focus on the EDSTAC Recommendations

Pubertal Development in Female Wistar Rats following Exposure to Propazine and Atrazine Biotransformation By-Products, Diamino-S-Chlorotriazine and Hydroxyatrazine

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