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Neurodevelopmental concepts of schizophrenia in the genome-wide association era: AKT/mTOR signaling as a pathological mediator of genetic and environmental programming during development

Schizophrenia research, 2020-03, Vol.217, p.95-104

2020

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PKBγ/AKT3 loss-of-function causes learning and memory deficits and deregulation of AKT/mTORC2 signaling: Relevance for schizophrenia

PloS one, 2017-05, Vol.12 (5), p.e0175993-e0175993

2017

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Transient overexposure of neuregulin 3 during early postnatal development impacts selective behaviors in adulthood

PloS one, 2014-08, Vol.9 (8), p.e104172

2014

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Toward Better Strategies for Understanding Disrupted Cortical Excitatory/Inhibitory Balance in Schizophrenia

Biological psychiatry (1969), 2018-04, Vol.83 (8), p.632-634

2018

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Disease-associated intronic variants in the ErbB4 gene are related to altered ErbB4 splice-variant expression in the brain in schizophrenia

Human molecular genetics, 2007-01, Vol.16 (2), p.129-141

2007

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Neuregulin 1-ErbB4-PI3K signaling in schizophrenia and phosphoinositide 3-kinase-p110δ inhibition as a potential therapeutic strategy

Proceedings of the National Academy of Sciences - PNAS, 2012-07, Vol.109 (30), p.12165-12170

2012

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Behavioral, Neurophysiological, and Synaptic Impairment in a Transgenic Neuregulin1 (NRG1-IV) Murine Schizophrenia Model

The Journal of neuroscience, 2016-04, Vol.36 (17), p.4859-4875

2016

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Neuregulin 1 Transcripts Are Differentially Expressed in Schizophrenia and Regulated by 5' SNPs Associated with the Disease

Proceedings of the National Academy of Sciences - PNAS, 2006-04, Vol.103 (17), p.6747-6752

2006

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Common genetic variation in Neuregulin 3 (NRG3) influences risk for schizophrenia and impacts NRG3 expression in human brain

Proceedings of the National Academy of Sciences - PNAS, 2010-08, Vol.107 (35), p.15619-15624

2010

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Genetic Neuropathology of Schizophrenia: New Approaches to an Old Question and New Uses for Postmortem Human Brains

Biological psychiatry (1969), 2011-01, Vol.69 (2), p.140-145

2011

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Characteristics of the cation cotransporter NKCC1 in human brain: alternate transcripts, expression in development, and potential relationships to brain function and schizophrenia

The Journal of neuroscience, 2014-04, Vol.34 (14), p.4929-4940

2014

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Molecular Cloning of a Brain-specific, Developmentally Regulated Neuregulin 1 (NRG1) Isoform and Identification of a Functional Promoter Variant Associated with Schizophrenia

The Journal of biological chemistry, 2007-08, Vol.282 (33), p.24343-24351

2007

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PI3Kinase-p110δ Overexpression Impairs Dendritic Morphogenesis and Increases Dendritic Spine Density

Frontiers in molecular neuroscience, 2020-02, Vol.13, p.29-29

2020

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Temporal Dynamics of the Neuregulin-ErbB Network in the Murine Prefrontal Cortex across the Lifespan

Cerebral cortex (New York, N.Y. 1991), 2020-05, Vol.30 (5), p.3325-3339

2020

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Early Parental Deprivation in the Marmoset Monkey Produces Long-Term Changes in Hippocampal Expression of Genes Involved in Synaptic Plasticity and Implicated in Mood Disorder

Neuropsychopharmacology (New York, N.Y.), 2009-05, Vol.34 (6), p.1381-1394

2009

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Effects of neuregulin 3 genotype on human prefrontal cortex physiology

The Journal of neuroscience, 2014-01, Vol.34 (3), p.1051-1056

2014

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Molecular cloning and characterization of the human ErbB4 gene: identification of novel splice isoforms in the developing and adult brain

PloS one, 2010-09, Vol.5 (9), p.e12924-e12924

2010

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Primate Early Life Stress Leads to Long-Term Mild Hippocampal Decreases in Corticosteroid Receptor Expression

Biological psychiatry (1969), 2010-06, Vol.67 (11), p.1106-1109

2010

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PKBβ/AKT2 deficiency impacts brain mTOR signaling, prefrontal cortical physiology, hippocampal plasticity and select murine behaviors

Molecular psychiatry, 2021-02, Vol.26 (2), p.411-428

2021

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Asymmetrical reductions of hippocampal NMDAR1 glutamate receptor mRNA in the psychoses

Neuroreport, 2001-09, Vol.12 (13), p.2971-2974

2001

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Neuregulin 1 and Schizophrenia: Genetics, Gene Expression, and Neurobiology

Biological psychiatry (1969), 2006-07, Vol.60 (2), p.132-140

2006

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A VNTR Regulates miR-137 Expression Through Novel Alternative Splicing and Contributes to Risk for Schizophrenia

Scientific reports, 2019-08, Vol.9 (1), p.11793-12, Article 11793

2019

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Choline, folic acid, Vitamin D, and fetal brain development in the psychosis spectrum

Schizophrenia research, 2022-09, Vol.247, p.16-25

2022

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Glutamate Receptors and Transporters in the Hippocampus in Schizophrenia

Annals of the New York Academy of Sciences, 2003-11, Vol.1003 (1), p.94-101

2003

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Transcription of PIK3CD in human brain and schizophrenia: regulation by proinflammatory cytokines

Human molecular genetics, 2019-10, Vol.28 (19), p.3188-3198

2019

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Neurodevelopmental concepts of schizophrenia in the genome-wide association era: AKT/mTOR signaling as a pathological mediator of genetic and environmental programming during development

PKBγ/AKT3 loss-of-function causes learning and memory deficits and deregulation of AKT/mTORC2 signaling: Relevance for schizophrenia

Transient overexposure of neuregulin 3 during early postnatal development impacts selective behaviors in adulthood

Toward Better Strategies for Understanding Disrupted Cortical Excitatory/Inhibitory Balance in Schizophrenia

Disease-associated intronic variants in the ErbB4 gene are related to altered ErbB4 splice-variant expression in the brain in schizophrenia

Neuregulin 1-ErbB4-PI3K signaling in schizophrenia and phosphoinositide 3-kinase-p110δ inhibition as a potential therapeutic strategy

Behavioral, Neurophysiological, and Synaptic Impairment in a Transgenic Neuregulin1 (NRG1-IV) Murine Schizophrenia Model

Neuregulin 1 Transcripts Are Differentially Expressed in Schizophrenia and Regulated by 5' SNPs Associated with the Disease

Common genetic variation in Neuregulin 3 (NRG3) influences risk for schizophrenia and impacts NRG3 expression in human brain

Genetic Neuropathology of Schizophrenia: New Approaches to an Old Question and New Uses for Postmortem Human Brains

Characteristics of the cation cotransporter NKCC1 in human brain: alternate transcripts, expression in development, and potential relationships to brain function and schizophrenia

Molecular Cloning of a Brain-specific, Developmentally Regulated Neuregulin 1 (NRG1) Isoform and Identification of a Functional Promoter Variant Associated with Schizophrenia

PI3Kinase-p110δ Overexpression Impairs Dendritic Morphogenesis and Increases Dendritic Spine Density

Temporal Dynamics of the Neuregulin-ErbB Network in the Murine Prefrontal Cortex across the Lifespan

Early Parental Deprivation in the Marmoset Monkey Produces Long-Term Changes in Hippocampal Expression of Genes Involved in Synaptic Plasticity and Implicated in Mood Disorder

Effects of neuregulin 3 genotype on human prefrontal cortex physiology

Molecular cloning and characterization of the human ErbB4 gene: identification of novel splice isoforms in the developing and adult brain

Primate Early Life Stress Leads to Long-Term Mild Hippocampal Decreases in Corticosteroid Receptor Expression

PKBβ/AKT2 deficiency impacts brain mTOR signaling, prefrontal cortical physiology, hippocampal plasticity and select murine behaviors

Asymmetrical reductions of hippocampal NMDAR1 glutamate receptor mRNA in the psychoses

Neuregulin 1 and Schizophrenia: Genetics, Gene Expression, and Neurobiology

A VNTR Regulates miR-137 Expression Through Novel Alternative Splicing and Contributes to Risk for Schizophrenia

Choline, folic acid, Vitamin D, and fetal brain development in the psychosis spectrum

Glutamate Receptors and Transporters in the Hippocampus in Schizophrenia

Transcription of PIK3CD in human brain and schizophrenia: regulation by proinflammatory cytokines

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