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Correlation of chemical structure with reproductive and developmental toxicity as it relates to the use of the threshold of toxicological concern
Regulatory toxicology and pharmacology, 2012-02, Vol.62 (1), p.160-182
2012
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Threshold of Toxicological Concern: Extending the chemical space by inclusion of a highly curated dataset for organosilicon compounds
Regulatory toxicology and pharmacology, 2021-12, Vol.127, p.105074-105074, Article 105074
2021
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Design and synthesis of novel N-sulfonyl-2-indole carboxamides as potent PPAR-γ binding agents with potential application to the treatment of osteoporosis
Bioorganic & medicinal chemistry letters, 2006-11, Vol.16 (21), p.5659-5663
2006
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Carboxylic Acid-Terminated Hyperbranched Polybenzoxazole and Its Polyarm-Star Block Copolymers
Macromolecules, 2009-03, Vol.42 (5), p.1541-1553
2009
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Potent and Selective Carboxylic Acid-Based Inhibitors of Matrix Metalloproteinases
Journal of medicinal chemistry, 2001-08, Vol.44 (16), p.2499-2502
2001
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Synthesis and evaluation of unsaturated caprolactams as interleukin-1β converting enzyme (ICE) inhibitors
Bioorganic & medicinal chemistry, 2007-02, Vol.15 (3), p.1311-1322
2007
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Synthesis and evaluation of novel 8,6-fused bicyclic peptidomimetic compounds as interleukin-1β converting enzyme inhibitors
Bioorganic & medicinal chemistry letters, 2005-12, Vol.15 (24), p.5434-5438
2005
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Discovery of novel conformationally restricted diazocan peptidomimetics as inhibitors of interleukin-1β synthesis
Bioorganic & medicinal chemistry letters, 2005-10, Vol.15 (19), p.4291-4294
2005
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Synthesis and evaluation of thiazepines as interleukin-1β converting enzyme (ICE) inhibitors
Bioorganic & medicinal chemistry letters, 2006-09, Vol.16 (18), p.4728-4732
2006
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Synthesis and evaluation of novel 8,5-fused bicyclic peptidomimetic compounds as interleukin-1β converting enzyme (ICE) inhibitors
Bioorganic & medicinal chemistry, 2006-12, Vol.14 (23), p.7880-7892
2006
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Synthesis and evaluation of novel 1-(2-acylhydrazinocarbonyl)-cycloalkyl carboxamides as interleukin-1β converting enzyme (ICE) inhibitors
Bioorganic & medicinal chemistry letters, 2006-08, Vol.16 (16), p.4233-4236
2006
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Synthesis and evaluation of tricyclic pyrrolopyrimidinones as dipeptide mimetics: Inhibition of interleukin-1β-converting enzyme
Bioorganic & medicinal chemistry letters, 2005-10, Vol.15 (19), p.4322-4326
2005
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Synthesis and evaluation of thiazepines as interleukin-1beta converting enzyme (ICE) inhibitors
Bioorganic & medicinal chemistry letters, 2006-09, Vol.16 (18), p.4728
2006
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Synthesis and evaluation of unsaturated caprolactams as interleukin-1beta converting enzyme (ICE) inhibitors
Bioorganic & medicinal chemistry, 2007-02, Vol.15 (3), p.1311-1322
2007
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Synthesis and evaluation of novel 8,5-fused bicyclic peptidomimetic compounds as interleukin-1beta converting enzyme (ICE) inhibitors
Bioorganic & medicinal chemistry, 2006-12, Vol.14 (23), p.7880
2006
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Synthesis and evaluation of tricyclic pyrrolopyrimidinones as dipeptide mimetics: inhibition of interleukin-1beta-converting enzyme
Bioorganic & medicinal chemistry letters, 2005-10, Vol.15 (19), p.4322
2005
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Synthesis and evaluation of novel 1-(2-acylhydrazinocarbonyl)-cycloalkyl carboxamides as interleukin-1beta converting enzyme (ICE) inhibitors
Bioorganic & medicinal chemistry letters, 2006-08, Vol.16 (16), p.4233
2006
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Synthesis and evaluation of novel 8,6-fused bicyclic peptidomimetic compounds as interleukin-1beta converting enzyme inhibitors
Bioorganic & medicinal chemistry letters, 2005-12, Vol.15 (24), p.5434-5438
2005
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Discovery of novel conformationally restricted diazocan peptidomimetics as inhibitors of interleukin-1beta synthesis
Bioorganic & medicinal chemistry letters, 2005-10, Vol.15 (19), p.4291
2005
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Framework for Identifying Chemicals with Structural Features Associated with the Potential to Act as Developmental or Reproductive Toxicants
Chemical research in toxicology, 2013-12, Vol.26 (12), p.1840-1861
2013
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Letter to the editor
Toxicological sciences, 2023-01, Vol.191 (1), p.192-192
2023
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Development of Orally Bioavailable Bicyclic Pyrazolones as Inhibitors of Tumor Necrosis Factor-α Production
Journal of medicinal chemistry, 2004-05, Vol.47 (11), p.2724-2727
2004
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The development of new isoxazolone based inhibitors of tumor necrosis factor-alpha (TNF-α) production
Bioorganic & medicinal chemistry letters, 2005-05, Vol.15 (9), p.2399-2403
2005
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Letter to the editor
Toxicological sciences, 2023-01, Vol.191 (1), p.192-192
2023
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Development of New Carboxylic Acid-Based MMP Inhibitors Derived from Functionalized Propargylglycines
Journal of medicinal chemistry, 2001-03, Vol.44 (7), p.1060-1071
2001
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