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Assessing the impact of nonspecific binding on oligonucleotide bioanalysis

Bioanalysis, 2021-08, Vol.13 (16), p.1233-1244

2021

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Quantitative N-Glycan Profiling of Therapeutic Monoclonal Antibodies Performed by Middle-Up Level HILIC-HRMS Analysis

Pharmaceutics, 2021-10, Vol.13 (11), p.1744

2021

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Pressure-Enhanced Liquid Chromatography, a Proof of Concept: Tuning Selectivity with Pressure Changes and Gradients

Analytical chemistry (Washington), 2022-06, Vol.94 (22), p.7877-7884

2022

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Theoretical study on solute migration and band broadening occurring in pressure-enhanced liquid chromatography

Journal of Chromatography A, 2023-03, Vol.1692, p.463872, Article 463872

2023

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High sensitivity acidic N-glycan profiling with MS-enhancing derivatization and mixed mode chromatography

Journal of chromatography. B, Analytical technologies in the biomedical and life sciences, 2022-02, Vol.1191, p.123120-123120, Article 123120

2022

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Negative gradient slope methods to improve the separation of closely eluting proteins

Journal of Chromatography A, 2021-01, Vol.1635, p.461743, Article 461743

2021

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The impact of low adsorption surfaces for the analysis of DNA and RNA oligonucleotides

Journal of Chromatography A, 2022-08, Vol.1677, p.463324, Article 463324

2022

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Size Exclusion and Ion Exchange Chromatographic Hardware Modified with a Hydrophilic Hybrid Surface

Analytical chemistry (Washington), 2022-02, Vol.94 (7), p.3360-3367

2022

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Towards a simple on-line coupling of ion exchange chromatography and native mass spectrometry for the detailed characterization of monoclonal antibodies

Journal of Chromatography A, 2021-10, Vol.1655, p.462499, Article 462499

2021

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Enhanced Detection of Low-Abundance Host Cell Protein Impurities in High-Purity Monoclonal Antibodies Down to 1 ppm Using Ion Mobility Mass Spectrometry Coupled with Multidimensional Liquid Chromatography

Analytical chemistry (Washington), 2015-10, Vol.87 (20), p.10283-10291

2015

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Rapid Preparation of Released N‑Glycans for HILIC Analysis Using a Labeling Reagent that Facilitates Sensitive Fluorescence and ESI-MS Detection

Analytical chemistry (Washington), 2015-05, Vol.87 (10), p.5401-5409

2015

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Using Hybrid Organic–Inorganic Surface Technology to Mitigate Analyte Interactions with Metal Surfaces in UHPLC

Analytical chemistry (Washington), 2021-04, Vol.93 (14), p.5773-5781

2021

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Ultra-short ion-exchange columns for fast charge variants analysis of therapeutic proteins

Journal of Chromatography A, 2021-11, Vol.1657, p.462568, Article 462568

2021

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High sensitivity LC-MS profiling of antibody-drug conjugates with difluoroacetic acid ion pairing

mAbs, 2019-11, Vol.11 (8), p.1358-1366

2019

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Use of Ultrashort Columns for Therapeutic Protein Separations. Part 1: Theoretical Considerations and Proof of Concept

Analytical chemistry (Washington), 2021-01, Vol.93 (3), p.1277-1284

2021

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Ratiometric Pulse–Chase Amidination Mass Spectrometry as a Probe of Biomolecular Complex Formation

Analytical chemistry (Washington), 2011-12, Vol.83 (23), p.9092-9099

2011

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Reducing metal-ion mediated adsorption of acidic peptides in RPLC-based assays using hybrid silica chromatographic surfaces

Journal of chromatography. B, Analytical technologies in the biomedical and life sciences, 2021-08, Vol.1179, p.122700-122700, Article 122700

2021

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Capillary liquid chromatography coupled with mass spectrometry for analysis of nanogram protein quantities on a wide-pore superficially porous particle column in top-down proteomics

Journal of chromatography. B, Analytical technologies in the biomedical and life sciences, 2023-01, Vol.1214, p.123566-123566, Article 123566

2023

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Optimizing test approaches for the detection of exposed metal surfaces within a chromatographic flow path

Journal of Chromatography A, 2022-03, Vol.1666, p.462855, Article 462855

2022

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Use of Ultra-short Columns for Therapeutic Protein Separations, Part 2: Designing the Optimal Column Dimension for Reversed-Phase Liquid Chromatography

Analytical chemistry (Washington), 2021-01, Vol.93 (3), p.1285-1293

2021

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Aptamer-based immunoaffinity LC-MS using an ultra-short column for rapid attomole level quantitation of intact mAbs

Journal of chromatography. B, Analytical technologies in the biomedical and life sciences, 2021-05, Vol.1173, p.122694-122694, Article 122694

2021

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Dynamics of Ribosomal Protein S1 on a Bacterial Ribosome with Cross-Linking and Mass Spectrometry

Molecular & cellular proteomics, 2012-12, Vol.11 (12), p.1965-1976

2012

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Novel Amidinating Cross-Linker for Facilitating Analyses of Protein Structures and Interactions

Analytical chemistry (Washington), 2010-09, Vol.82 (18), p.7736-7743

2010

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Structural Analysis of a Prokaryotic Ribosome Using a Novel Amidinating Cross-Linker and Mass Spectrometry

Journal of proteome research, 2011-08, Vol.10 (8), p.3604-3616

2011

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High-Resolution Peptide Mapping Separations with MS-Friendly Mobile Phases and Charge-Surface-Modified C18

Analytical chemistry (Washington), 2013-07, Vol.85 (14), p.6936-6944

2013

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Assessing the impact of nonspecific binding on oligonucleotide bioanalysis

Quantitative N-Glycan Profiling of Therapeutic Monoclonal Antibodies Performed by Middle-Up Level HILIC-HRMS Analysis

Pressure-Enhanced Liquid Chromatography, a Proof of Concept: Tuning Selectivity with Pressure Changes and Gradients

Theoretical study on solute migration and band broadening occurring in pressure-enhanced liquid chromatography

High sensitivity acidic N-glycan profiling with MS-enhancing derivatization and mixed mode chromatography

Negative gradient slope methods to improve the separation of closely eluting proteins

The impact of low adsorption surfaces for the analysis of DNA and RNA oligonucleotides

Size Exclusion and Ion Exchange Chromatographic Hardware Modified with a Hydrophilic Hybrid Surface

Towards a simple on-line coupling of ion exchange chromatography and native mass spectrometry for the detailed characterization of monoclonal antibodies

Enhanced Detection of Low-Abundance Host Cell Protein Impurities in High-Purity Monoclonal Antibodies Down to 1 ppm Using Ion Mobility Mass Spectrometry Coupled with Multidimensional Liquid Chromatography

Rapid Preparation of Released N‑Glycans for HILIC Analysis Using a Labeling Reagent that Facilitates Sensitive Fluorescence and ESI-MS Detection

Using Hybrid Organic–Inorganic Surface Technology to Mitigate Analyte Interactions with Metal Surfaces in UHPLC

Ultra-short ion-exchange columns for fast charge variants analysis of therapeutic proteins

High sensitivity LC-MS profiling of antibody-drug conjugates with difluoroacetic acid ion pairing

Use of Ultrashort Columns for Therapeutic Protein Separations. Part 1: Theoretical Considerations and Proof of Concept

Ratiometric Pulse–Chase Amidination Mass Spectrometry as a Probe of Biomolecular Complex Formation

Reducing metal-ion mediated adsorption of acidic peptides in RPLC-based assays using hybrid silica chromatographic surfaces

Capillary liquid chromatography coupled with mass spectrometry for analysis of nanogram protein quantities on a wide-pore superficially porous particle column in top-down proteomics

Optimizing test approaches for the detection of exposed metal surfaces within a chromatographic flow path

Use of Ultra-short Columns for Therapeutic Protein Separations, Part 2: Designing the Optimal Column Dimension for Reversed-Phase Liquid Chromatography

Aptamer-based immunoaffinity LC-MS using an ultra-short column for rapid attomole level quantitation of intact mAbs

Dynamics of Ribosomal Protein S1 on a Bacterial Ribosome with Cross-Linking and Mass Spectrometry

Novel Amidinating Cross-Linker for Facilitating Analyses of Protein Structures and Interactions

Structural Analysis of a Prokaryotic Ribosome Using a Novel Amidinating Cross-Linker and Mass Spectrometry

High-Resolution Peptide Mapping Separations with MS-Friendly Mobile Phases and Charge-Surface-Modified C18

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