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Chronic hepatitis B: Virology, natural history, current management and a glimpse at future opportunities

Antiviral research, 2015-09, Vol.121, p.47-58

2015

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Population-Wide Genetic Risk Prediction of Complex Diseases: A Pilot Feasibility Study in Macau Population for Precision Public Healthcare Planning

Scientific reports, 2018-01, Vol.8 (1), p.1853-11, Article 1853

2018

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Specific, sensitive and accurate liquid chromatographic–tandem mass spectrometric method for the measurement of ribavirin in rat and monkey plasma

Journal of chromatography. B, Analytical technologies in the biomedical and life sciences, 2002-11, Vol.779 (2), p.241-248

2002

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A Novel Mechanism to Ensure Terminal Initiation by Hepatitis C Virus NS5B Polymerase

Virology (New York, N.Y.), 2001-06, Vol.285 (1), p.6-11

2001

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RNAi-based treatment of chronically infected patients and chimpanzees reveals that integrated hepatitis B virus DNA is a source of HBsAg

Science translational medicine, 2017-09, Vol.9 (409)

2017

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Discovery of Encequidar, First-in-Class Intestine Specific P‑glycoprotein Inhibitor

Journal of medicinal chemistry, 2021-04, Vol.64 (7), p.3677-3693

2021

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Discovery and Characterization of Potent Dual P‑Glycoprotein and CYP3A4 Inhibitors: Design, Synthesis, Cryo-EM Analysis, and Biological Evaluations

Journal of medicinal chemistry, 2022-01, Vol.65 (1), p.191-216

2022

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Synthetic RNAi triggers and their use in chronic hepatitis B therapies with curative intent

Antiviral research, 2015-09, Vol.121, p.97-108

2015

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MERS coronavirus induces apoptosis in kidney and lung by upregulating Smad7 and FGF2

Nature microbiology, 2016-02, Vol.1, p.16004

2016

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Safety, Tolerability, and Pharmacokinetics of ARC‐520 Injection, an RNA Interference‐Based Therapeutic for the Treatment of Chronic Hepatitis B Virus Infection, in Healthy Volunteers

Clinical pharmacology in drug development, 2017-07, Vol.6 (4), p.350-362

2017

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Jinhua Qinggan granules for non-hospitalized COVID-19 patients: A double-blind, placebo-controlled, and randomized controlled trial

Frontiers in medicine, 2022-08, Vol.9

2022

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Specific, sensitive and accurate LC–MS/MS method for the measurement of levovirin in rat and monkey plasma

Journal of pharmaceutical and biomedical analysis, 2002-09, Vol.30 (2), p.239-246

2002

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A novel recombinant single-chain hepatitis C virus NS3-NS4A protein with improved helicase activity

Protein science, 1999-06, Vol.8 (6), p.1332-1341

1999

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The broad-spectrum antiviral ribonucleoside ribavirin is an RNA virus mutagen

Nature medicine, 2000-12, Vol.6 (12), p.1375-1379

2000

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KX2-361: a novel orally bioavailable small molecule dual Src/tubulin inhibitor that provides long term survival in a murine model of glioblastoma

Journal of neuro-oncology, 2018-12, Vol.140 (3), p.519-527

2018

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Mechanism of action of ribavirin in the combination treatment of chronic HCV infection

Hepatology (Baltimore, Md.), 2002-05, Vol.35 (5), p.1002-1009

2002

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Evolutionary relationship of hepatitis C, pesti-, flavi-, plantviruses, and newly discovered GB hepatitis agents

FEBS letters, 1996-01, Vol.378 (3), p.232-234

1996

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Phase 1 clinical trial to assess safety and efficacy of NY-ESO-1-specific TCR T cells in HLA-A∗02:01 patients with advanced soft tissue sarcoma

Cell reports. Medicine, 2023-08, Vol.4 (8), p.101133-101133, Article 101133

2023

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Discovery of 4‑Aryl‑N‑arylcarbonyl-2-aminothiazoles as Hec1/Nek2 Inhibitors. Part I: Optimization of in Vitro Potencies and Pharmacokinetic Properties

Journal of medicinal chemistry, 2014-05, Vol.57 (10), p.4098-4110

2014

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Discovery of T-1101 tosylate as a first-in-class clinical candidate for Hec1/Nek2 inhibition in cancer therapy

European journal of medicinal chemistry, 2020-04, Vol.191, p.112118-112118, Article 112118

2020

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Alzheimer's disease: insights for risk evaluation and prevention in the Chinese population and the need for a comprehensive programme in Hong Kong/China

Hong Kong medical journal = Xianggang yi xue za zhi, 2018-10, Vol.24 (5), p.492-500

2018

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Chronic hepatitis B: Virology, natural history, current management and a glimpse at future opportunities

Efficacy of Clarithromycin-Naproxen-Oseltamivir Combination in the Treatment of Patients Hospitalized for Influenza A(H3N2) Infection

Population-Wide Genetic Risk Prediction of Complex Diseases: A Pilot Feasibility Study in Macau Population for Precision Public Healthcare Planning

Specific, sensitive and accurate liquid chromatographic–tandem mass spectrometric method for the measurement of ribavirin in rat and monkey plasma

A Novel Mechanism to Ensure Terminal Initiation by Hepatitis C Virus NS5B Polymerase

RNAi-based treatment of chronically infected patients and chimpanzees reveals that integrated hepatitis B virus DNA is a source of HBsAg

Discovery of Encequidar, First-in-Class Intestine Specific P‑glycoprotein Inhibitor

Discovery and Characterization of Potent Dual P‑Glycoprotein and CYP3A4 Inhibitors: Design, Synthesis, Cryo-EM Analysis, and Biological Evaluations

Synthetic RNAi triggers and their use in chronic hepatitis B therapies with curative intent

Efficacy of Clarithromycin-Naproxen-Oseltamivir Combination in the Treatment of Patients Hospitalized for Influenza A(H3N2) Infection: An Open-label Randomized, Controlled, Phase IIb/III Trial

Topical imiquimod before intradermal trivalent influenza vaccine for protection against heterologous non-vaccine and antigenically drifted viruses: a single-centre, double-blind, randomised, controlled phase 2b/3 trial

MERS coronavirus induces apoptosis in kidney and lung by upregulating Smad7 and FGF2

Safety, Tolerability, and Pharmacokinetics of ARC‐520 Injection, an RNA Interference‐Based Therapeutic for the Treatment of Chronic Hepatitis B Virus Infection, in Healthy Volunteers

Jinhua Qinggan granules for non-hospitalized COVID-19 patients: A double-blind, placebo-controlled, and randomized controlled trial

Specific, sensitive and accurate LC–MS/MS method for the measurement of levovirin in rat and monkey plasma

A novel recombinant single-chain hepatitis C virus NS3-NS4A protein with improved helicase activity

The broad-spectrum antiviral ribonucleoside ribavirin is an RNA virus mutagen

KX2-361: a novel orally bioavailable small molecule dual Src/tubulin inhibitor that provides long term survival in a murine model of glioblastoma

Mechanism of action of ribavirin in the combination treatment of chronic HCV infection

Evolutionary relationship of hepatitis C, pesti-, flavi-, plantviruses, and newly discovered GB hepatitis agents

Phase 1 clinical trial to assess safety and efficacy of NY-ESO-1-specific TCR T cells in HLA-A∗02:01 patients with advanced soft tissue sarcoma

Discovery of 4‑Aryl‑N‑arylcarbonyl-2-aminothiazoles as Hec1/Nek2 Inhibitors. Part I: Optimization of in Vitro Potencies and Pharmacokinetic Properties

Discovery of T-1101 tosylate as a first-in-class clinical candidate for Hec1/Nek2 inhibition in cancer therapy

Alzheimer's disease: insights for risk evaluation and prevention in the Chinese population and the need for a comprehensive programme in Hong Kong/China

Variations in the viral NS5B region in Japanese patients with chronic hepatitis C virus genotype 1b infection. No specific amino acid substitution was identified as determinants of treatment response to interferon/ribavirin combination therapy

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