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Potential function for the Huntingtin protein as a scaffold for selective autophagy

Proceedings of the National Academy of Sciences - PNAS, 2014-11, Vol.111 (47), p.16889-16894

2014

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TRiC subunits enhance BDNF axonal transport and rescue striatal atrophy in Huntington’s disease

Proceedings of the National Academy of Sciences - PNAS, 2016-09, Vol.113 (38), p.E5655-E5664

2016

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Calcium Dynamics in Astrocytes During Cell Injury

Frontiers in bioengineering and biotechnology, 2020-08, Vol.8, p.912-912

2020

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Developmental alterations in Huntington's disease neural cells and pharmacological rescue in cells and mice

Nature neuroscience, 2017-05, Vol.20 (5), p.648-660

2017

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Huntington's disease mice and human brain tissue exhibit increased G3BP1 granules and TDP43 mislocalization

The Journal of clinical investigation, 2021-06, Vol.131 (12), p.1-15

2021

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IKK phosphorylates Huntingtin and targets it for degradation by the proteasome and lysosome

The Journal of cell biology, 2009-12, Vol.187 (7), p.1083-1099

2009

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Huntingtin contains an ubiquitin-binding domain and regulates lysosomal targeting of mitochondrial and RNA-binding proteins

Proceedings of the National Academy of Sciences - PNAS, 2024-08, Vol.121 (32), p.e2319091121

2024

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IKKβ slows Huntington’s disease progression in R6/1 mice

Proceedings of the National Academy of Sciences - PNAS, 2019-05, Vol.116 (22), p.10952-10961

2019

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Diminished LC3-Associated Phagocytosis by Huntington's Disease Striatal Astrocytes

Journal of Huntington's disease, 2022-01, Vol.11 (1), p.25-33

2022

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Striatal Mutant Huntingtin Protein Levels Decline with Age in Homozygous Huntington's Disease Knock-In Mouse Models

Journal of Huntington's disease, 2018-01, Vol.7 (2), p.137-150

2018

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Huntington's disease mice and human brain tissue exhibit increased G3BP1 granules and TDP43 mislocalization

The Journal of clinical investigation, 2021-06, Vol.131 (12)

2021

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Selective radiolabeling of cell surface proteins to a high specific activity

Biochemistry (Easton), 1987-02, Vol.26 (3), p.743-750

1987

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Urinary Excretion of Zinc, Copper and Iron in the Streptozotocin-Diabetic Rat

The Journal of nutrition, 1984-01, Vol.114 (1), p.224-233

1984

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Monoclonal antibodies to protease nexin 1 that differentially block its inhibition of target proteases

Biochemistry (Easton), 1988-03, Vol.27 (6), p.2173-2176

1988

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Injury‐Related Factors and Conditions Down‐Regulate the Thrombin Receptor (PAR‐1) in a Human Neuronal Cell Line

Journal of neurochemistry, 1998-09, Vol.71 (3), p.1034-1050

1998

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Protease Nexin-1, an Antithrombin with Neurite Outgrowth Activity, is Reduced in Alzheimer Disease

Proceedings of the National Academy of Sciences - PNAS, 1989-11, Vol.86 (21), p.8284-8288

1989

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Protease nexin-1, a thrombin inhibitor, is regulated by interleukin-1 and dexamethasone in normal human fibroblasts

The Journal of biological chemistry, 1993-09, Vol.268 (25), p.18966-18974

1993

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Inhibitors of Urokinase and Thrombin in Cultured Neural Cells

Journal of neurochemistry, 1991-01, Vol.56 (1), p.234-242

1991

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Association between HLA‐B1502 Allele and Antiepileptic Drug‐Induced Cutaneous Reactions in Han Chinese

Epilepsia (Copenhagen), 2007-05, Vol.48 (5), p.1015-1018

2007

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Premature Mortality and Comorbidities in Young-onset Diabetes: A 7-Year Prospective Analysis

The American journal of medicine, 2014-07, Vol.127 (7), p.616-624

2014

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Clinical Predictors and Long-term Impact of Acute Kidney Injury on Progression of Diabetic Kidney Disease in Chinese Patients With Type 2 Diabetes

Diabetes (New York, N.Y.), 2022-03, Vol.71 (3), p.520-529

2022

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Use of net reclassification improvement (NRI) method confirms the utility of combined genetic risk score to predict type 2 diabetes

PloS one, 2013-12, Vol.8 (12), p.e83093-e83093

2013

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The Lancet Commission on diabetes: using data to transform diabetes care and patient lives

The Lancet (British edition), 2020-12, Vol.396 (10267), p.2019-2082

2020

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Metabolic Syndrome Predicts New Onset of Chronic Kidney Disease in 5,829 Patients With Type 2 Diabetes: A 5-year prospective analysis of the Hong Kong Diabetes Registry

Diabetes care, 2008-12, Vol.31 (12), p.2357-2361

2008

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Association of HLA‐B22 serotype with SARS‐CoV‐2 susceptibility in Hong Kong Chinese patients

HLA, 2021-02, Vol.97 (2), p.127-132

2021

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Potential function for the Huntingtin protein as a scaffold for selective autophagy

TRiC subunits enhance BDNF axonal transport and rescue striatal atrophy in Huntington’s disease

Calcium Dynamics in Astrocytes During Cell Injury

Developmental alterations in Huntington's disease neural cells and pharmacological rescue in cells and mice

Huntington's disease mice and human brain tissue exhibit increased G3BP1 granules and TDP43 mislocalization

IKK phosphorylates Huntingtin and targets it for degradation by the proteasome and lysosome

Huntingtin contains an ubiquitin-binding domain and regulates lysosomal targeting of mitochondrial and RNA-binding proteins

IKKβ slows Huntington’s disease progression in R6/1 mice

Diminished LC3-Associated Phagocytosis by Huntington's Disease Striatal Astrocytes

Striatal Mutant Huntingtin Protein Levels Decline with Age in Homozygous Huntington's Disease Knock-In Mouse Models

Huntington's disease mice and human brain tissue exhibit increased G3BP1 granules and TDP43 mislocalization

Selective radiolabeling of cell surface proteins to a high specific activity

Urinary Excretion of Zinc, Copper and Iron in the Streptozotocin-Diabetic Rat

Monoclonal antibodies to protease nexin 1 that differentially block its inhibition of target proteases

Injury‐Related Factors and Conditions Down‐Regulate the Thrombin Receptor (PAR‐1) in a Human Neuronal Cell Line

Protease Nexin-1, an Antithrombin with Neurite Outgrowth Activity, is Reduced in Alzheimer Disease

Protease nexin-1, a thrombin inhibitor, is regulated by interleukin-1 and dexamethasone in normal human fibroblasts

Inhibitors of Urokinase and Thrombin in Cultured Neural Cells

Association between HLA‐B1502 Allele and Antiepileptic Drug‐Induced Cutaneous Reactions in Han Chinese

Premature Mortality and Comorbidities in Young-onset Diabetes: A 7-Year Prospective Analysis

Clinical Predictors and Long-term Impact of Acute Kidney Injury on Progression of Diabetic Kidney Disease in Chinese Patients With Type 2 Diabetes

Use of net reclassification improvement (NRI) method confirms the utility of combined genetic risk score to predict type 2 diabetes

The Lancet Commission on diabetes: using data to transform diabetes care and patient lives

Metabolic Syndrome Predicts New Onset of Chronic Kidney Disease in 5,829 Patients With Type 2 Diabetes: A 5-year prospective analysis of the Hong Kong Diabetes Registry

Association of HLA‐B22 serotype with SARS‐CoV‐2 susceptibility in Hong Kong Chinese patients

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