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Activin A more prominently regulates muscle mass in primates than does GDF8

Nature communications, 2017-04, Vol.8 (1), p.15153-15153, Article 15153

2017

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Insulin-like Growth Factor-1 (IGF-1) Inversely Regulates Atrophy-induced Genes via the Phosphatidylinositol 3-Kinase/Akt/Mammalian Target of Rapamycin (PI3K/Akt/mTOR) Pathway

The Journal of biological chemistry, 2005-01, Vol.280 (4), p.2737-2744

2005

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TNF-α inhibitors for type 1 diabetes: exploring the path to a pivotal clinical trial

Frontiers in immunology, 2024-10, Vol.15

2024

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Role of the F-box Protein Skp2 in Lymphomagenesis

Proceedings of the National Academy of Sciences - PNAS, 2001-02, Vol.98 (5), p.2515-2520

2001

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Genetic Deletion of Trb3, the Mammalian Drosophila tribbles Homolog, Displays Normal Hepatic Insulin Signaling and Glucose Homeostasis

Diabetes (New York, N.Y.), 2007-05, Vol.56 (5), p.1350-1356

2007

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Role of F-Box Protein βTrcp1 in Mammary Gland Development and Tumorigenesis

Molecular and Cellular Biology, 2004-09, Vol.24 (18), p.8184-8194

2004

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Navigating Two Roads to Glucose Normalization in Diabetes: Automated Insulin Delivery Devices and Cell Therapy

Cell metabolism, 2019-03, Vol.29 (3), p.545-563

2019

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3D Bioprinting and Translation of Beta Cell Replacement Therapies for Type 1 Diabetes

Tissue engineering. Part B, Reviews, 2021-06, Vol.27 (3), p.238-252

2021

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During muscle atrophy, thick, but not thin, filament components are degraded by MuRF1-dependent ubiquitylation

The Journal of cell biology, 2009-06, Vol.185 (6), p.1083-1095

2009

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Islet cells in T1D: from recent advances to novel therapies - a symposium-based roadmap for future

Journal of endocrinology, 2023-07

2023

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Islet cells in human type 1 diabetes: from recent advances to novel therapies – a symposium-based roadmap for future research

Journal of endocrinology, 2023-09, Vol.259 (1)

2023

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182-OR: C-Peptide and Metabolic Outcomes in Immunotherapy Studies of New-Onset Type 1 Diabetes

Diabetes (New York, N.Y.), 2023-06, Vol.72 (Supplement_1), p.1

2023

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Evidence for C-Peptide as a Validated Surrogate to Predict Clinical Benefits in Trials of Disease-Modifying Therapies for Type 1 Diabetes

Diabetes (New York, N.Y.), 2024-06, Vol.73 (6), p.823-833

2024

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The E3 Ligase MuRF1 Degrades Myosin Heavy Chain Protein in Dexamethasone-Treated Skeletal Muscle

Cell metabolism, 2007-11, Vol.6 (5), p.376-385

2007

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Identification of Ubiquitin Ligases Required for Skeletal Muscle Atrophy

Science (American Association for the Advancement of Science), 2001-11, Vol.294 (5547), p.1704-1708

2001

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Myostatin blockade with a fully human monoclonal antibody induces muscle hypertrophy and reverses muscle atrophy in young and aged mice

Skeletal muscle, 2015-10, Vol.5 (1), p.34-34, Article 34

2015

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Cohort profile: the ‘Biomarkers of heterogeneity in type 1 diabetes’ study—a national prospective cohort study of clinical and metabolic phenotyping of individuals with long-standing type 1 diabetes in the Netherlands

BMJ open, 2024-06, Vol.14 (6), p.e082453

2024

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The de-ubiquitinating enzyme Unp interacts with the retinoblastoma protein

Oncogene, 2001-09, Vol.20 (39), p.5538-5542

2001

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C-peptide and metabolic outcomes in trials of disease modifying therapy in new-onset type 1 diabetes: an individual participant meta-analysis

The lancet. Diabetes & endocrinology, 2023-12, Vol.11 (12), p.915-925

2023

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Myostatin deficiency but not anti-myostatin blockade induces marked proteomic changes in mouse skeletal muscle

Proteomics (Weinheim), 2016-07, Vol.16 (14), p.2019-2027

2016

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Conditionals by inversion provide a universal method for the generation of conditional alleles

Proceedings of the National Academy of Sciences - PNAS, 2013-08, Vol.110 (34), p.E3179-E3188

2013

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Gene expression signature predicts rate of type 1 diabetes progression

EBioMedicine, 2023-06, Vol.92, p.104625-104625, Article 104625

2023

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Activin A more prominently regulates muscle mass in primates than does GDF8

Insulin-like Growth Factor-1 (IGF-1) Inversely Regulates Atrophy-induced Genes via the Phosphatidylinositol 3-Kinase/Akt/Mammalian Target of Rapamycin (PI3K/Akt/mTOR) Pathway

TNF-α inhibitors for type 1 diabetes: exploring the path to a pivotal clinical trial

Role of the F-box Protein Skp2 in Lymphomagenesis

Genetic Deletion of Trb3, the Mammalian Drosophila tribbles Homolog, Displays Normal Hepatic Insulin Signaling and Glucose Homeostasis

Role of F-Box Protein βTrcp1 in Mammary Gland Development and Tumorigenesis

Navigating Two Roads to Glucose Normalization in Diabetes: Automated Insulin Delivery Devices and Cell Therapy

3D Bioprinting and Translation of Beta Cell Replacement Therapies for Type 1 Diabetes

During muscle atrophy, thick, but not thin, filament components are degraded by MuRF1-dependent ubiquitylation

Islet cells in T1D: from recent advances to novel therapies - a symposium-based roadmap for future

Islet cells in human type 1 diabetes: from recent advances to novel therapies – a symposium-based roadmap for future research

182-OR: C-Peptide and Metabolic Outcomes in Immunotherapy Studies of New-Onset Type 1 Diabetes

Evidence for C-Peptide as a Validated Surrogate to Predict Clinical Benefits in Trials of Disease-Modifying Therapies for Type 1 Diabetes

Defining Outcomes for β-cell Replacement Therapy in the Treatment of Diabetes: A Consensus Report on the Igls Criteria From the IPITA/EPITA Opinion Leaders Workshop

The E3 Ligase MuRF1 Degrades Myosin Heavy Chain Protein in Dexamethasone-Treated Skeletal Muscle

Identification of Ubiquitin Ligases Required for Skeletal Muscle Atrophy

Defining outcomes for β‐cell replacement therapy in the treatment of diabetes: a consensus report on the Igls criteria from the IPITA/EPITA opinion leaders workshop

Harnessing cellular therapeutics for type 1 diabetes mellitus: progress, challenges, and the road ahead

Myostatin blockade with a fully human monoclonal antibody induces muscle hypertrophy and reverses muscle atrophy in young and aged mice

Cohort profile: the ‘Biomarkers of heterogeneity in type 1 diabetes’ study—a national prospective cohort study of clinical and metabolic phenotyping of individuals with long-standing type 1 diabetes in the Netherlands

The de-ubiquitinating enzyme Unp interacts with the retinoblastoma protein

C-peptide and metabolic outcomes in trials of disease modifying therapy in new-onset type 1 diabetes: an individual participant meta-analysis

Myostatin deficiency but not anti-myostatin blockade induces marked proteomic changes in mouse skeletal muscle

Conditionals by inversion provide a universal method for the generation of conditional alleles

Gene expression signature predicts rate of type 1 diabetes progression

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