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Advances in inflammatory bowel disease pathogenesis: linking host genetics and the microbiome

Gut, 2013-10, Vol.62 (10), p.1505-1510

2013

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Mechanisms and function of autophagy in intestinal disease

Autophagy, 2018-02, Vol.14 (2), p.216-220

2018

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Atg16L1 T300A variant decreases selective autophagy resulting in altered cytokine signaling and decreased antibacterial defense

Proceedings of the National Academy of Sciences - PNAS, 2014-05, Vol.111 (21), p.7741-7746

2014

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Meiotic gatekeeper STRA8 suppresses autophagy by repressing Nr1d1 expression during spermatogenesis in mice

PLoS genetics, 2019-05, Vol.15 (5), p.e1008084-e1008084

2019

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Genetic Coding Variant in GPR65 Alters Lysosomal pH and Links Lysosomal Dysfunction with Colitis Risk

Immunity (Cambridge, Mass.), 2016-06, Vol.44 (6), p.1392-1405

2016

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The Crohn's disease polymorphism, ATG16L1 T300A, alters the gut microbiota and enhances the local Th1/Th17 response

eLife, 2019-01, Vol.8

2019

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A Noncanonical Autophagy Pathway Restricts Toxoplasma gondii Growth in a Strain-Specific Manner in IFN-γ-Activated Human Cells

mBio, 2015-09, Vol.6 (5), p.e01157-e01115

2015

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A flexible model of HIV-1 latency permitting evaluation of many primary CD4 T-cell reservoirs

PloS one, 2012-01, Vol.7 (1), p.e30176-e30176

2012

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RNF166 Determines Recruitment of Adaptor Proteins during Antibacterial Autophagy

Cell reports (Cambridge), 2016-11, Vol.17 (9), p.2183-2194

2016

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Distinct Tissue-Specific Roles for the Disease-Associated Autophagy Genes ATG16L2 and ATG16L1

The Journal of immunology (1950), 2019-10, Vol.203 (7), p.1820-1829

2019

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Small-molecule enhancers of autophagy modulate cellular disease phenotypes suggested by human genetics

Proceedings of the National Academy of Sciences - PNAS, 2015-08, Vol.112 (31), p.E4281-E4287

2015

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Calcium/calcineurin synergizes with prostratin to promote NF-κB dependent activation of latent HIV

PloS one, 2013, Vol.8 (10), p.e77749

2013

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Activation of HIV transcription by the viral Tat protein requires a demethylation step mediated by lysine-specific demethylase 1 (LSD1/KDM1)

PLoS pathogens, 2011-08, Vol.7 (8), p.e1002184

2011

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Nuclear retention of multiply spliced HIV-1 RNA in resting CD4+ T cells

PLoS pathogens, 2006-07, Vol.2 (7), p.e68-e68

2006

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Transcription factor TFEB cell-autonomously modulates susceptibility to intestinal epithelial cell injury in vivo

Scientific reports, 2017-10, Vol.7 (1), p.13938-13, Article 13938

2017

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Integrated Genomics of Crohn’s Disease Risk Variant Identifies a Role for CLEC12A in Antibacterial Autophagy

Cell reports (Cambridge), 2015-06, Vol.11 (12), p.1905-1918

2015

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Neutralizing Antibodies Do Not Mediate Suppression of Human Immunodeficiency Virus Type 1 in Elite Suppressors or Selection of Plasma Virus Variants in Patients on Highly Active Antiretroviral Therapy

Journal of Virology, 2006-05, Vol.80 (10), p.4758-4770

2006

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Elite suppressor-derived HIV-1 envelope glycoproteins exhibit reduced entry efficiency and kinetics

PLoS pathogens, 2009-04, Vol.5 (4), p.e1000377-e1000377

2009

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Selective Modulation of Autophagy, Innate Immunity, and Adaptive Immunity by Small Molecules

ACS chemical biology, 2013-12, Vol.8 (12), p.2724-2733

2013

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Analysis of Human Immunodeficiency Virus Type 1 Transcriptional Elongation in Resting CD4+ T Cells In Vivo

Journal of Virology, 2004-09, Vol.78 (17), p.9105-9114

2004

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An image-based genetic assay identifies genes in T1D susceptibility loci controlling cellular antiviral immunity in mouse

PloS one, 2014-09, Vol.9 (9), p.e108777

2014

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Abortive HIV Infection Mediates CD4 T Cell Depletion and Inflammation in Human Lymphoid Tissue

Cell, 2010-11, Vol.143 (5), p.789-801

2010

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HIV-1 replicative fitness in elite controllers

Current opinion in HIV & AIDS, 2011-05, Vol.6 (3), p.214-220

2011

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Identification of Two APOBEC3F Splice Variants Displaying HIV-1 Antiviral Activity and Contrasting Sensitivity to Vif[S]

The Journal of biological chemistry, 2010-09, Vol.285 (38), p.29326-29335

2010

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Advances in inflammatory bowel disease pathogenesis: linking host genetics and the microbiome

Mechanisms and function of autophagy in intestinal disease

Atg16L1 T300A variant decreases selective autophagy resulting in altered cytokine signaling and decreased antibacterial defense

Meiotic gatekeeper STRA8 suppresses autophagy by repressing Nr1d1 expression during spermatogenesis in mice

Genetic Coding Variant in GPR65 Alters Lysosomal pH and Links Lysosomal Dysfunction with Colitis Risk

The Crohn's disease polymorphism, ATG16L1 T300A, alters the gut microbiota and enhances the local Th1/Th17 response

A Noncanonical Autophagy Pathway Restricts Toxoplasma gondii Growth in a Strain-Specific Manner in IFN-γ-Activated Human Cells

A flexible model of HIV-1 latency permitting evaluation of many primary CD4 T-cell reservoirs

RNF166 Determines Recruitment of Adaptor Proteins during Antibacterial Autophagy

Distinct Tissue-Specific Roles for the Disease-Associated Autophagy Genes ATG16L2 and ATG16L1

Small-molecule enhancers of autophagy modulate cellular disease phenotypes suggested by human genetics

Calcium/calcineurin synergizes with prostratin to promote NF-κB dependent activation of latent HIV

Activation of HIV transcription by the viral Tat protein requires a demethylation step mediated by lysine-specific demethylase 1 (LSD1/KDM1)

Nuclear retention of multiply spliced HIV-1 RNA in resting CD4+ T cells

Transcription factor TFEB cell-autonomously modulates susceptibility to intestinal epithelial cell injury in vivo

Integrated Genomics of Crohn’s Disease Risk Variant Identifies a Role for CLEC12A in Antibacterial Autophagy

Neutralizing Antibodies Do Not Mediate Suppression of Human Immunodeficiency Virus Type 1 in Elite Suppressors or Selection of Plasma Virus Variants in Patients on Highly Active Antiretroviral Therapy

Elite suppressor-derived HIV-1 envelope glycoproteins exhibit reduced entry efficiency and kinetics

Selective Modulation of Autophagy, Innate Immunity, and Adaptive Immunity by Small Molecules

Analysis of Human Immunodeficiency Virus Type 1 Transcriptional Elongation in Resting CD4+ T Cells In Vivo

IL-1-driven stromal-neutrophil interactions define a subset of patients with inflammatory bowel disease that does not respond to therapies

An image-based genetic assay identifies genes in T1D susceptibility loci controlling cellular antiviral immunity in mouse

Abortive HIV Infection Mediates CD4 T Cell Depletion and Inflammation in Human Lymphoid Tissue

HIV-1 replicative fitness in elite controllers

Identification of Two APOBEC3F Splice Variants Displaying HIV-1 Antiviral Activity and Contrasting Sensitivity to Vif[S]

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