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Exosomes in the pathogenesis, diagnostics and therapeutics of liver diseases

Journal of hepatology, 2013-09, Vol.59 (3), p.621-625

2013

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The Cholangiopathies

Mayo Clinic proceedings, 2015-06, Vol.90 (6), p.791-800

2015

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Primary Sclerosing Cholangitis Risk Estimate Tool (PREsTo) Predicts Outcomes of the Disease: A Derivation and Validation Study Using Machine Learning

Hepatology (Baltimore, Md.), 2020-01, Vol.71 (1), p.214-224

2020

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Absence of the intestinal microbiota exacerbates hepatobiliary disease in a murine model of primary sclerosing cholangitis

Hepatology (Baltimore, Md.), 2016-01, Vol.63 (1), p.185-196

2016

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Cholangiocyte senescence by way of N‐ras activation is a characteristic of primary sclerosing cholangitis

Hepatology (Baltimore, Md.), 2014-06, Vol.59 (6), p.2263-2275

2014

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Macrophages contribute to the pathogenesis of sclerosing cholangitis in mice

Journal of hepatology, 2018-09, Vol.69 (3), p.676-686

2018

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A Cellular Micro-RNA, let-7i, Regulates Toll-like Receptor 4 Expression and Contributes to Cholangiocyte Immune Responses against Cryptosporidium parvum Infection

The Journal of biological chemistry, 2007-09, Vol.282 (39), p.28929-28938

2007

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HDAC6 Inhibition Restores Ciliary Expression and Decreases Tumor Growth

Cancer research (Chicago, Ill.), 2013-04, Vol.73 (7), p.2259-2270

2013

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Release of luminal exosomes contributes to TLR4-mediated epithelial antimicrobial defense

PLoS pathogens, 2013-04, Vol.9 (4), p.e1003261-e1003261

2013

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Therapeutic Targets in Polycystic Liver Disease

Current drug targets, 2017-01, Vol.18 (8), p.950-957

2017

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The dynamic biliary epithelia: Molecules, pathways, and disease

Journal of hepatology, 2013-03, Vol.58 (3), p.575-582

2013

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MicroRNA‐506 promotes primary biliary cholangitis–like features in cholangiocytes and immune activation

Hepatology (Baltimore, Md.), 2018-04, Vol.67 (4), p.1420-1440

2018

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Polycystic liver disease: The interplay of genes causative for hepatic and renal cystogenesis

Hepatology (Baltimore, Md.), 2018-06, Vol.67 (6), p.2462-2464

2018

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Randomized Clinical Trial of Long-Acting Somatostatin for Autosomal Dominant Polycystic Kidney and Liver Disease

Journal of the American Society of Nephrology, 2010-06, Vol.21 (6), p.1052-1061

2010

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Performance of magnetic resonance elastography in primary sclerosing cholangitis

Journal of gastroenterology and hepatology, 2016-06, Vol.31 (6), p.1184-1190

2016

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Primary Sclerosing Cholangitis

The New England journal of medicine, 2016-09, Vol.375 (12), p.1161-1170

2016

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Cholangiocyte autophagy contributes to hepatic cystogenesis in polycystic liver disease and represents a potential therapeutic target

Hepatology (Baltimore, Md.), 2018-03, Vol.67 (3), p.1088-1108

2018

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Ciliary subcellular localization of TGR5 determines the cholangiocyte functional response to bile acid signaling

American journal of physiology: Gastrointestinal and liver physiology, 2013-06, Vol.304 (11), p.G1013-G1024

2013

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Immunotherapy-based targeting of MSLN⁺ activated portal fibroblasts is a strategy for treatment of cholestatic liver fibrosis

Proceedings of the National Academy of Sciences - PNAS, 2021-07, Vol.118 (29), p.1-12

2021

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Primary Cilia in Tumor Biology: The Primary Cilium as a Therapeutic Target in Cholangiocarcinoma

Current drug targets, 2017-01, Vol.18 (8), p.958-963

2017

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Polarized human cholangiocytes release distinct populations of apical and basolateral small extracellular vesicles

Molecular biology of the cell, 2020-10, Vol.31 (22), p.2463-2474

2020

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The cholangiopathies: Disorders of biliary epithelia

Gastroenterology (New York, N.Y. 1943), 2004-11, Vol.127 (5), p.1565-1577

2004

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Cholangiocyte primary cilia in liver health and disease

Developmental dynamics, 2008-08, Vol.237 (8), p.2007-2012

2008

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Combination of a Histone Deacetylase 6 Inhibitor and a Somatostatin Receptor Agonist Synergistically Reduces Hepatorenal Cystogenesis in an Animal Model of Polycystic Liver Disease

The American journal of pathology, 2018-04, Vol.188 (4), p.981-994

2018

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Characterization of PKD Protein-Positive Exosome-Like Vesicles

Journal of the American Society of Nephrology, 2009-02, Vol.20 (2), p.278-288

2009

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Exosomes in the pathogenesis, diagnostics and therapeutics of liver diseases

The Cholangiopathies

Primary Sclerosing Cholangitis Risk Estimate Tool (PREsTo) Predicts Outcomes of the Disease: A Derivation and Validation Study Using Machine Learning

Absence of the intestinal microbiota exacerbates hepatobiliary disease in a murine model of primary sclerosing cholangitis

Cholangiocyte senescence by way of N‐ras activation is a characteristic of primary sclerosing cholangitis

Macrophages contribute to the pathogenesis of sclerosing cholangitis in mice

A Cellular Micro-RNA, let-7i, Regulates Toll-like Receptor 4 Expression and Contributes to Cholangiocyte Immune Responses against Cryptosporidium parvum Infection

HDAC6 Inhibition Restores Ciliary Expression and Decreases Tumor Growth

Release of luminal exosomes contributes to TLR4-mediated epithelial antimicrobial defense

Therapeutic Targets in Polycystic Liver Disease

The dynamic biliary epithelia: Molecules, pathways, and disease

MicroRNA‐506 promotes primary biliary cholangitis–like features in cholangiocytes and immune activation

Polycystic liver disease: The interplay of genes causative for hepatic and renal cystogenesis

Randomized Clinical Trial of Long-Acting Somatostatin for Autosomal Dominant Polycystic Kidney and Liver Disease

Performance of magnetic resonance elastography in primary sclerosing cholangitis

Primary Sclerosing Cholangitis

Cholangiocyte autophagy contributes to hepatic cystogenesis in polycystic liver disease and represents a potential therapeutic target

Ciliary subcellular localization of TGR5 determines the cholangiocyte functional response to bile acid signaling

Immunotherapy-based targeting of MSLN⁺ activated portal fibroblasts is a strategy for treatment of cholestatic liver fibrosis

Primary Cilia in Tumor Biology: The Primary Cilium as a Therapeutic Target in Cholangiocarcinoma

Polarized human cholangiocytes release distinct populations of apical and basolateral small extracellular vesicles

The cholangiopathies: Disorders of biliary epithelia

Cholangiocyte primary cilia in liver health and disease

Combination of a Histone Deacetylase 6 Inhibitor and a Somatostatin Receptor Agonist Synergistically Reduces Hepatorenal Cystogenesis in an Animal Model of Polycystic Liver Disease

Characterization of PKD Protein-Positive Exosome-Like Vesicles

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