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Harnessing adipogenesis to prevent obesity

Adipocyte, 2019-01, Vol.8 (1), p.98-104

2019

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Activation of the PDGFRα-Nrf2 pathway mediates impaired adipocyte differentiation in bone marrow mesenchymal stem cells lacking Nck1

Cell communication and signaling, 2020-02, Vol.18 (1), p.26-26, Article 26

2020

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mTORC1 and CK2 coordinate ternary and eIF4F complex assembly

Nature communications, 2016-04, Vol.7 (1), p.11127-11127, Article 11127

2016

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USP19 deubiquitinating enzyme inhibits muscle cell differentiation by suppressing unfolded-protein response signaling

Molecular biology of the cell, 2015-03, Vol.26 (5), p.913-923

2015

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Nck1 Deficiency Impairs Adipogenesis by Activation of PDGFRα in Preadipocytes

iScience, 2018-08, Vol.6, p.22-37

2018

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Nck2 promotes human melanoma cell proliferation, migration and invasion in vitro and primary melanoma-derived tumor growth in vivo

BMC cancer, 2011-10, Vol.11 (1), p.443-443, Article 443

2011

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Nck-dependent activation of extracellular signal-regulated kinase-1 and regulation of cell survival during endoplasmic reticulum stress

Molecular biology of the cell, 2004-09, Vol.15 (9), p.4248-4260

2004

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PERK leads a hub dictating pancreatic β cell homoeostasis

Biology of the cell, 2018-02, Vol.110 (2), p.27-32

2018

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Gab1 scaffold regulates RTK-dependent dorsal ruffle formation through the adaptor Nck

Journal of cell science, 2010-04, Vol.123 (8), p.1306-1319

2010

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The Adaptor Protein Nck Interacts with Fas Ligand: Guiding the Death Factor to the Cytotoxic Immunological Synapse

Proceedings of the National Academy of Sciences - PNAS, 2006-04, Vol.103 (15), p.5911-5916

2006

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The Adaptor Protein Nck-1 Couples the Netrin-1 Receptor DCC (Deleted in Colorectal Cancer) to the Activation of the Small GTPase Rac1 through an Atypical Mechanism

The Journal of biological chemistry, 2002-10, Vol.277 (40), p.37788-37797

2002

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Nck-1 Antagonizes the Endoplasmic Reticulum Stress-induced Inhibition of Translation

The Journal of biological chemistry, 2004-03, Vol.279 (10), p.9662-9671

2004

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Nck1 deficiency improves pancreatic β cell survival to diabetes-relevant stresses by modulating PERK activation and signaling

Cellular signalling, 2015-12, Vol.27 (12), p.2555-2567

2015

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Interaction of Nck1 and PERK phosphorylated at Y 561 negatively modulates PERK activity and PERK regulation of pancreatic β-cell proinsulin content

Molecular biology of the cell, 2014-03, Vol.25 (5), p.702-711

2014

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SHP-1 Binds and Negatively Modulates the c-Kit Receptor by Interaction with Tyrosine 569 in the c-Kit Juxtamembrane Domain

Molecular and Cellular Biology, 1998-04, Vol.18 (4), p.2089-2099

1998

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IRE1α links Nck1 deficiency to attenuated PTP1B expression in HepG2 cells

Cellular signalling, 2017-08, Vol.36, p.79-90

2017

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Modulation of Protein Translation by Nck-1

Proceedings of the National Academy of Sciences - PNAS, 2002-04, Vol.99 (8), p.5406-5411

2002

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Nck in a Complex Containing the Catalytic Subunit of Protein Phosphatase 1 Regulates Eukaryotic Initiation Factor 2α Signaling and Cell Survival to Endoplasmic Reticulum Stress

The Journal of biological chemistry, 2006-09, Vol.281 (36), p.26633-26644

2006

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Deletion of inositol-requiring enzyme-1α in podocytes disrupts glomerular capillary integrity and autophagy

Molecular biology of the cell, 2017-06, Vol.28 (12), p.1636-1651

2017

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Nck1—an Adaptor Protein Modulating Expression of the Endoplasmic Reticulum (ER) Stress Sensor IRE1α

The FASEB journal, 2012-04, Vol.26 (S1)

2012

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Casein Kinase Iγ2 Impairs Fibroblasts Actin Stress Fibers Formation and Delays Cell Cycle Progression in G1

International Journal of Cell Biology, 2012, Vol.2012, p.684684-684684

2012

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Peptide-based sequestration of the adaptor protein Nck1 in pancreatic β cells enhances insulin biogenesis and protects against diabetogenic stresses

The Journal of biological chemistry, 2018-08, Vol.293 (32), p.12516-12524

2018

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A Casein Kinase I Activity Is Constitutively Associated with Nck

The Journal of biological chemistry, 1997-01, Vol.272 (5), p.2688-2694

1997

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Dissecting the molecular mechanisms that impair stress granule formation in aging cells

Biochimica et biophysica acta. Molecular cell research, 2017-03, Vol.1864 (3), p.475-486

2017

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Interaction of Nck1 and PERK phosphorylated at Y⁵⁶¹ negatively modulates PERK activity and PERK regulation of pancreatic β-cell proinsulin content

Molecular biology of the cell, 2014-03, Vol.25 (5), p.702-711

2014

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Harnessing adipogenesis to prevent obesity

Activation of the PDGFRα-Nrf2 pathway mediates impaired adipocyte differentiation in bone marrow mesenchymal stem cells lacking Nck1

mTORC1 and CK2 coordinate ternary and eIF4F complex assembly

USP19 deubiquitinating enzyme inhibits muscle cell differentiation by suppressing unfolded-protein response signaling

Nck1 Deficiency Impairs Adipogenesis by Activation of PDGFRα in Preadipocytes

Nck2 promotes human melanoma cell proliferation, migration and invasion in vitro and primary melanoma-derived tumor growth in vivo

Nck-dependent activation of extracellular signal-regulated kinase-1 and regulation of cell survival during endoplasmic reticulum stress

PERK leads a hub dictating pancreatic β cell homoeostasis

Gab1 scaffold regulates RTK-dependent dorsal ruffle formation through the adaptor Nck

The Adaptor Protein Nck Interacts with Fas Ligand: Guiding the Death Factor to the Cytotoxic Immunological Synapse

The Adaptor Protein Nck-1 Couples the Netrin-1 Receptor DCC (Deleted in Colorectal Cancer) to the Activation of the Small GTPase Rac1 through an Atypical Mechanism

Nck-1 Antagonizes the Endoplasmic Reticulum Stress-induced Inhibition of Translation

Nck1 deficiency improves pancreatic β cell survival to diabetes-relevant stresses by modulating PERK activation and signaling

Interaction of Nck1 and PERK phosphorylated at Y 561 negatively modulates PERK activity and PERK regulation of pancreatic β-cell proinsulin content

SHP-1 Binds and Negatively Modulates the c-Kit Receptor by Interaction with Tyrosine 569 in the c-Kit Juxtamembrane Domain

IRE1α links Nck1 deficiency to attenuated PTP1B expression in HepG2 cells

Modulation of Protein Translation by Nck-1

Nck in a Complex Containing the Catalytic Subunit of Protein Phosphatase 1 Regulates Eukaryotic Initiation Factor 2α Signaling and Cell Survival to Endoplasmic Reticulum Stress

Deletion of inositol-requiring enzyme-1α in podocytes disrupts glomerular capillary integrity and autophagy

Nck1—an Adaptor Protein Modulating Expression of the Endoplasmic Reticulum (ER) Stress Sensor IRE1α

Casein Kinase Iγ2 Impairs Fibroblasts Actin Stress Fibers Formation and Delays Cell Cycle Progression in G1

Peptide-based sequestration of the adaptor protein Nck1 in pancreatic β cells enhances insulin biogenesis and protects against diabetogenic stresses

A Casein Kinase I Activity Is Constitutively Associated with Nck

Dissecting the molecular mechanisms that impair stress granule formation in aging cells

Interaction of Nck1 and PERK phosphorylated at Y⁵⁶¹ negatively modulates PERK activity and PERK regulation of pancreatic β-cell proinsulin content

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