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SEP-363856, a Novel Psychotropic Agent with a Unique, Non-D 2 Receptor Mechanism of Action

The Journal of pharmacology and experimental therapeutics, 2019-10, Vol.371 (1), p.1-14

2019

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Discovery of Allosteric Potentiators for the Metabotropic Glutamate 2 Receptor: Synthesis and Subtype Selectivity of N-(4-(2-Methoxyphenoxy)phenyl)-N-(2,2,2− trifluoroethylsulfonyl)pyrid-3-ylmethylamine

Journal of medicinal chemistry, 2003-07, Vol.46 (15), p.3189-3192

2003

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Novel human D-amino acid oxidase inhibitors stabilize an active-site lid-open conformation

Bioscience reports, 2014-08, Vol.34 (4), p.e00133

2014

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Structural, Kinetic, and Pharmacodynamic Mechanisms of d‑Amino Acid Oxidase Inhibition by Small Molecules

Journal of medicinal chemistry, 2013-05, Vol.56 (9), p.3710-3724

2013

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Pharmacodynamic effects of a D-amino acid oxidase inhibitor indicate a spinal site of action in rat models of neuropathic pain

The Journal of pharmacology and experimental therapeutics, 2013-06, Vol.345 (3), p.502-511

2013

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Effects of D‐amino acid oxidase inhibition on memory performance and long‐term potentiation in vivo

Pharmacology research & perspectives, 2013-10, Vol.1 (1), p.e00007-n/a

2013

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Niacin mediates lipolysis in adipose tissue through its G-protein coupled receptor HM74A

Biochemical and biophysical research communications, 2005-08, Vol.334 (2), p.729-732

2005

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Nerve Growth Factor Gene Expression in the Developing Rat Brain

Science (American Association for the Advancement of Science), 1986-10, Vol.234 (4774), p.352-355

1986

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Discovery of allosteric potentiators for the metabotropic glutamate 2 receptor : Synthesis and subtype selectivity of N-(4-(2-methoxyphenoxy)phenyl)-N-(2,2,2-trifluoroethylsulfonyl)pyrid-3-ylmethyl- amine

Journal of medicinal chemistry, 2003-07, Vol.46 (15), p.3189-3192

2003

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TrkB Isoforms with Distinct Neurotrophin Specificities Are Expressed in Predominantly Nonoverlapping Populations of Avian Dorsal Root Ganglion Neurons

The Journal of neuroscience, 1999-06, Vol.19 (12), p.4739-4747

1999

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In vivo phenotypic drug discovery: applying a behavioral assay to the discovery and optimization of novel antipsychotic agents

MedChemComm, 2016-01, Vol.7 (6), p.1093-1101

2016

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In vivo phenotypic drug discovery: applying a behavioral assay to the discovery and optimization of novel antipsychotic agentsThe authors declare no competing interests.Electronic supplementary information (ESI) available: Supplementary data associated with this article can be found in the online version. See DOI: 10.1039/c6md00128a

2016-06

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In vivophenotypic drug discovery: applying a behavioral assay to the discovery and optimization of novel antipsychotic agents

MedChemComm, 2016-06, Vol.7 (6), p.1093-1101

2016

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Neural differentiation promoted by truncated trkC receptors in collaboration with p75(NTR)

Developmental biology, 1998-09, Vol.201 (1), p.90-100

1998

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Immortalized young adult neurons from the septal region: generation and characterization

Brain research. Developmental brain research, 1990-03, Vol.52 (1), p.219-228

1990

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Expression of Full-Length trkB Receptors by Reactive Astrocytes after Chronic CNS Injury

Experimental neurology, 1997-12, Vol.148 (2), p.558-567

1997

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Expression of TrkB receptor isoforms in the developing avian visual system

The Journal of neuroscience, 1996-03, Vol.16 (5), p.1740-1752

1996

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trkC-Mediated NT-3 Signaling Is Required for the Early Development of a Subpopulation of Neurogenic Neural Crest Cells

Developmental biology, 1995-12, Vol.172 (2), p.602-613

1995

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Molecular cloning of the rat integrin α1-subunit : a receptor for laminin and collagen

The Journal of cell biology, 1990, Vol.111 (2), p.709-720

1990

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Molecular Cloning of the Rat Integrin α 1-Subunit: A Receptor for Laminin and Collagen

The Journal of cell biology, 1990-08, Vol.111 (2), p.709-720

1990

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Structure and developmental expression of the nerve growth factor receptor in the chicken central nervous system

Neuron (Cambridge, Mass.), 1989-02, Vol.2 (2), p.1123-1134

1989

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Neuronal properties and trophic activities of immortalized hippocampal cells from embryonic and young adult mice

The Journal of neuroscience, 1990-06, Vol.10 (6), p.1779-1787

1990

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Neural Differentiation Promoted by Truncated trkC Receptors in Collaboration with p75NTR

Developmental biology, 1998-09, Vol.201 (1), p.90-100

1998

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Neural Differentiation Promoted by Truncated trkC Receptors in Collaboration with p75 NTR

Developmental biology, 1998, Vol.201 (1), p.90-100

1998

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Generation of the truncated form of the nerve growth factor receptor by rat Schwann cells. Evidence for post-translational processing

The Journal of biological chemistry, 1991-10, Vol.266 (28), p.19113-19119

1991

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SEP-363856, a Novel Psychotropic Agent with a Unique, Non-D 2 Receptor Mechanism of Action

Discovery of Allosteric Potentiators for the Metabotropic Glutamate 2 Receptor: Synthesis and Subtype Selectivity of N-(4-(2-Methoxyphenoxy)phenyl)-N-(2,2,2− trifluoroethylsulfonyl)pyrid-3-ylmethylamine

Novel human D-amino acid oxidase inhibitors stabilize an active-site lid-open conformation

Structural, Kinetic, and Pharmacodynamic Mechanisms of d‑Amino Acid Oxidase Inhibition by Small Molecules

Pharmacodynamic effects of a D-amino acid oxidase inhibitor indicate a spinal site of action in rat models of neuropathic pain

Effects of D‐amino acid oxidase inhibition on memory performance and long‐term potentiation in vivo

Niacin mediates lipolysis in adipose tissue through its G-protein coupled receptor HM74A

Nerve Growth Factor Gene Expression in the Developing Rat Brain

Discovery of allosteric potentiators for the metabotropic glutamate 2 receptor : Synthesis and subtype selectivity of N-(4-(2-methoxyphenoxy)phenyl)-N-(2,2,2-trifluoroethylsulfonyl)pyrid-3-ylmethyl- amine

TrkB Isoforms with Distinct Neurotrophin Specificities Are Expressed in Predominantly Nonoverlapping Populations of Avian Dorsal Root Ganglion Neurons

In vivo phenotypic drug discovery: applying a behavioral assay to the discovery and optimization of novel antipsychotic agents

In vivophenotypic drug discovery: applying a behavioral assay to the discovery and optimization of novel antipsychotic agents

Neural differentiation promoted by truncated trkC receptors in collaboration with p75(NTR)

Immortalized young adult neurons from the septal region: generation and characterization

Expression of Full-Length trkB Receptors by Reactive Astrocytes after Chronic CNS Injury

Expression of TrkB receptor isoforms in the developing avian visual system

trkC-Mediated NT-3 Signaling Is Required for the Early Development of a Subpopulation of Neurogenic Neural Crest Cells

Molecular cloning of the rat integrin α1-subunit : a receptor for laminin and collagen

Molecular Cloning of the Rat Integrin α 1-Subunit: A Receptor for Laminin and Collagen

Structure and developmental expression of the nerve growth factor receptor in the chicken central nervous system

Neuronal properties and trophic activities of immortalized hippocampal cells from embryonic and young adult mice

Neural Differentiation Promoted by Truncated trkC Receptors in Collaboration with p75NTR

Neural Differentiation Promoted by Truncated trkC Receptors in Collaboration with p75 NTR

Generation of the truncated form of the nerve growth factor receptor by rat Schwann cells. Evidence for post-translational processing

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