UB Paderborn / Katalog / Suche / in CDI

Synthesis/biological evaluation of hydroxamic acids and their prodrugs as inhibitors for Botulinum neurotoxin A light chain

Bioorganic & medicinal chemistry, 2014-02, Vol.22 (3), p.1208-1217

2014

Volltextzugriff (PDF)

Building a Three-Dimensional Model of CYP2C9 Inhibition Using the Autocorrelator: An Autonomous Model Generator

Journal of chemical information and modeling, 2012-05, Vol.52 (5), p.1328-1336

2012

Volltextzugriff (PDF)

Hydra: A Self Regenerating High Performance Computing Grid for Drug Discovery

Journal of Chemical Information and Modeling, 2008-04, Vol.48 (4), p.811-816

2008

Volltextzugriff (PDF)

C‑Terminus of Botulinum A Protease Has Profound and Unanticipated Kinetic Consequences upon the Catalytic Cleft

ACS medicinal chemistry letters, 2013-02, Vol.4 (2), p.283-287

2013

Volltextzugriff (PDF)

Discovery of KIN-3248, An Irreversible, Next Generation FGFR Inhibitor for the Treatment of Advanced Tumors Harboring FGFR2 and/or FGFR3 Gene Alterations

Journal of medicinal chemistry, 2024-02, Vol.67 (3), p.1734-1746

2024

Volltextzugriff (PDF)

The Irreversible FGFR Inhibitor KIN-3248 Overcomes FGFR2 Kinase Domain Mutations

Clinical cancer research, 2024-05, Vol.30 (10), p.2181

2024

Volltextzugriff (PDF)

Rational discovery of a highly novel and selective mTOR inhibitor

Bioorganic & medicinal chemistry letters, 2019-11, Vol.29 (21), p.126659-126659, Article 126659

2019

Volltextzugriff (PDF)

Synthesis and Molecular Modeling Provide Insight into a Pseudomonas aeruginosa Quorum Sensing Conundrum

Journal of the American Chemical Society, 2011-03, Vol.133 (11), p.3840-3842

2011

Volltextzugriff (PDF)

Pyrrolo[1,2- b]pyridazin-2-ones as potent inhibitors of HCV NS5B polymerase

Bioorganic & medicinal chemistry, 2008-06, Vol.18 (12), p.3616-3621

2008

Volltextzugriff (PDF)

Novel HCV NS5B polymerase inhibitors derived from 4-(1',1'-dioxo-1',4'- dihydro-1' lambda super(6)-benzo[1',2',4']thiadiazin-3'-yl)-5-hydroxy-2H- pyridazin-3-ones: Part 4. Optimization of DMPK properties

Bioorganic & medicinal chemistry, 2008-06, Vol.18 (11), p.3421-3426

2008

Volltextzugriff (PDF)

5,5'- and 6,6'-Dialkyl-5,6-dihydro-1H-pyridin-2-ones as potent inhibitors of HCV NS5B polymerase

Bioorganic & medicinal chemistry letters, 2009-11, Vol.19 (21), p.6047-6052

2009

Volltextzugriff (PDF)

Novel HCV NS5B polymerase inhibitors derived from 4-(1',1'-dioxo-1 '4'-dihydro-1λ-benzo[1',2',4']thiadiazin-3-yl)-5-hydroxy-2H-pyridazin-3-ones: Part 4. Optimization of DMPK properties

Bioorganic & medicinal chemistry letters, 2008-06, Vol.18 (11), p.3421-3426

2008

Volltextzugriff (PDF)

4-(1,1-Dioxo-1,4-dihydro-1λ6-benzo[1,4]thiazin-3-yl)-5-hydroxy-2H-pyridazin-3-ones as potent inhibitors of HCV NS5B polymerase

Bioorganic & medicinal chemistry letters, 2008-08, Vol.18 (16), p.4628-4632

2008

Volltextzugriff (PDF)

Illuminator: increasing synergies between medicinal and computational chemists

In silico biology, 2011, Vol.11 (1-2), p.83

2011

Volltextzugriff (PDF)

5,5′- and 6,6′-Dialkyl-5,6-dihydro-1 H-pyridin-2-ones as potent inhibitors of HCV NS5B polymerase

Bioorganic & medicinal chemistry letters, 2009, Vol.19 (21), p.6047-6052

2009

Volltextzugriff (PDF)

4-(1,1-Dioxo-1,4-dihydro-1 lambda super(6)-benzo[1,4]thiazin-3-yl)-5-hydroxy- 2H-pyridazin-3-ones as potent inhibitors of HCV NS5B polymerase

Bioorganic & medicinal chemistry, 2008-08, Vol.18 (16), p.4628-4632

2008

Volltextzugriff (PDF)

Disarming Pseudomonas aeruginosa Virulence Factor LasB by Leveraging a Caenorhabditis elegans Infection Model

Chemistry & biology, 2015-04, Vol.22 (4), p.483-491

2015

Volltextzugriff (PDF)

Novel HCV NS5B polymerase inhibitors derived from 4-(1′,1′-dioxo-1′,4′-dihydro-1′λ 6-benzo[1′,2′,4′]thiadiazin-3′-yl)-5-hydroxy-2 H-pyridazin-3-ones: Part 4. Optimization of DMPK properties

Bioorganic & medicinal chemistry letters, 2008, Vol.18 (11), p.3421-3426

2008

Volltextzugriff (PDF)

4-(1,1-Dioxo-1,4-dihydro-1λ 6-benzo[1,4]thiazin-3-yl)-5-hydroxy-2 H-pyridazin-3-ones as potent inhibitors of HCV NS5B polymerase

Bioorganic & medicinal chemistry letters, 2008, Vol.18 (16), p.4628-4632

2008

Volltextzugriff (PDF)

Computational combinatorial methods in virtual library design

Lardy, Matthew Alan

2006

Volltextzugriff (PDF)

ChemInform Abstract: Hydra: A Self Regenerating High Performance Computing Grid for Drug Discovery

ChemInform, 2008-07, Vol.39 (29), p.no-no

2008

Volltextzugriff (PDF)

Long-term Piliostigma reticulatum intercropping in the Sahel: Crop productivity, carbon sequestration, nutrient cycling, and soil quality

Agriculture, ecosystems & environment, 2017-05, Vol.242, p.9-22

2017

Volltextzugriff (PDF)

An overlooked local resource: Shrub-intercropping for food production, drought resistance and ecosystem restoration in the Sahel

Agriculture, ecosystems & environment, 2021-10, Vol.319, p.107523, Article 107523

2021

Volltextzugriff (PDF)

GCT-29. DOES TUMOUR MARKER DECLINE PREDICT OUTCOME IN INTRACRANIAL NON-GERMINOMATOUS GERM CELL TUMOURS (NGGCTs)?

Neuro-oncology (Charlottesville, Va.), 2020-12, Vol.22 (Supplement_3), p.iii333-iii334

2020

Volltextzugriff (PDF)

Effect of feeding flax or linseed meal on progesterone clearance rate in ovariectomized ewes

Domestic animal endocrinology, 2008-08, Vol.35 (2), p.164-169

2008

Volltextzugriff (PDF)

Menü

Weitere Dienste

Einstellungen

Synthesis/biological evaluation of hydroxamic acids and their prodrugs as inhibitors for Botulinum neurotoxin A light chain

Building a Three-Dimensional Model of CYP2C9 Inhibition Using the Autocorrelator: An Autonomous Model Generator

Hydra: A Self Regenerating High Performance Computing Grid for Drug Discovery

C‑Terminus of Botulinum A Protease Has Profound and Unanticipated Kinetic Consequences upon the Catalytic Cleft

Discovery of KIN-3248, An Irreversible, Next Generation FGFR Inhibitor for the Treatment of Advanced Tumors Harboring FGFR2 and/or FGFR3 Gene Alterations

The Irreversible FGFR Inhibitor KIN-3248 Overcomes FGFR2 Kinase Domain Mutations

Rational discovery of a highly novel and selective mTOR inhibitor

Synthesis and Molecular Modeling Provide Insight into a Pseudomonas aeruginosa Quorum Sensing Conundrum

Pyrrolo[1,2- b]pyridazin-2-ones as potent inhibitors of HCV NS5B polymerase

Novel HCV NS5B polymerase inhibitors derived from 4-(1',1'-dioxo-1',4'- dihydro-1' lambda super(6)-benzo[1',2',4']thiadiazin-3'-yl)-5-hydroxy-2H- pyridazin-3-ones: Part 4. Optimization of DMPK properties

5,5'- and 6,6'-Dialkyl-5,6-dihydro-1H-pyridin-2-ones as potent inhibitors of HCV NS5B polymerase

Novel HCV NS5B polymerase inhibitors derived from 4-(1',1'-dioxo-1 '4'-dihydro-1λ-benzo[1',2',4']thiadiazin-3-yl)-5-hydroxy-2H-pyridazin-3-ones: Part 4. Optimization of DMPK properties

4-(1,1-Dioxo-1,4-dihydro-1λ6-benzo[1,4]thiazin-3-yl)-5-hydroxy-2H-pyridazin-3-ones as potent inhibitors of HCV NS5B polymerase

Illuminator: increasing synergies between medicinal and computational chemists

5,5′- and 6,6′-Dialkyl-5,6-dihydro-1 H-pyridin-2-ones as potent inhibitors of HCV NS5B polymerase

4-(1,1-Dioxo-1,4-dihydro-1 lambda super(6)-benzo[1,4]thiazin-3-yl)-5-hydroxy- 2H-pyridazin-3-ones as potent inhibitors of HCV NS5B polymerase

Disarming Pseudomonas aeruginosa Virulence Factor LasB by Leveraging a Caenorhabditis elegans Infection Model

Novel HCV NS5B polymerase inhibitors derived from 4-(1′,1′-dioxo-1′,4′-dihydro-1′λ 6-benzo[1′,2′,4′]thiadiazin-3′-yl)-5-hydroxy-2 H-pyridazin-3-ones: Part 4. Optimization of DMPK properties

4-(1,1-Dioxo-1,4-dihydro-1λ 6-benzo[1,4]thiazin-3-yl)-5-hydroxy-2 H-pyridazin-3-ones as potent inhibitors of HCV NS5B polymerase

Computational combinatorial methods in virtual library design

ChemInform Abstract: Hydra: A Self Regenerating High Performance Computing Grid for Drug Discovery

Long-term Piliostigma reticulatum intercropping in the Sahel: Crop productivity, carbon sequestration, nutrient cycling, and soil quality

An overlooked local resource: Shrub-intercropping for food production, drought resistance and ecosystem restoration in the Sahel

GCT-29. DOES TUMOUR MARKER DECLINE PREDICT OUTCOME IN INTRACRANIAL NON-GERMINOMATOUS GERM CELL TUMOURS (NGGCTs)?

Effect of feeding flax or linseed meal on progesterone clearance rate in ovariectomized ewes

Suchergebnisse filtern