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Amyloid-beta Targeted Therapeutic Approaches for Alzheimer’s Disease: Long Road Ahead

Current drug targets, 2022-08, Vol.23 (11), p.1040-1056

2022

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Design, synthesis, and biological evaluation of novel androst-17β-amide structurally related compounds as dual 5α-reductase inhibitors and androgen receptor antagonists

Journal of enzyme inhibition and medicinal chemistry, 2019-01, Vol.34 (1), p.1597-1606

2019

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Therapeutic Strategies Targeting Amyloid-β Receptors and Transporters in Alzheimer’s Disease

Journal of Alzheimer's disease, 2021-01, Vol.79 (4), p.1429-1442

2021

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Drug development for Alzheimer's disease: review

Journal of drug targeting, 2019-02, Vol.27 (2), p.164-173

2019

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Gpn2 and Rba50 Directly Participate in the Assembly of the Rpb3 Subcomplex in the Biogenesis of RNA Polymerase II

Molecular and cellular biology, 2018-07, Vol.38 (13)

2018

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Structure-activity relationships of 2, 4-disubstituted pyrimidines as dual ERα/VEGFR-2 ligands with anti-breast cancer activity

European journal of medicinal chemistry, 2018-04, Vol.150, p.783-795

2018

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AMPK alleviates oxidative stress‑induced premature senescence via inhibition of NF-κB/STAT3 axis-mediated positive feedback loop

Mechanisms of ageing and development, 2020-10, Vol.191, p.111347-111347, Article 111347

2020

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Identification of novel Aβ-LilrB2 inhibitors as potential therapeutic agents for Alzheimer's disease

Molecular and cellular neuroscience, 2021-07, Vol.114, p.103630-103630, Article 103630

2021

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Rapid and highly specific detection of site-specific 5-hydroxymethylcytosine based on peroxotungstate oxidation and mismatch ligation-based LAMP

RSC advances, 2022-07, Vol.12 (31), p.19885-19889

2022

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(m)RVD-hemopressin (α) and (m)VD-hemopressin (α) improve the memory-impairing effect of scopolamine in novel object and object location recognition tasks in mice

Peptides (New York, N.Y. : 1980), 2021-02, Vol.136, p.170442-170442, Article 170442

2021

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Design and synthesis of novel steroidal imidazoles as dual inhibitors of AR/CYP17 for the treatment of prostate cancer

Steroids, 2019-10, Vol.150, p.108384, Article 108384

2019

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Potential Astrocytic Receptors and Transporters in the Pathogenesis of Alzheimer's Disease

Journal of Alzheimer's disease, 2019-01, Vol.67 (4), p.1109-1122

2019

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Effect of (m)VD-hemopressin against Aβ1-42-induced oxidative stress and apoptosis in mouse hippocampal neurons

Peptides (New York, N.Y. : 1980), 2020-02, Vol.124, p.170185, Article 170185

2020

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Design, synthesis and biological evaluation of novel 2-methoxyestradiol analogs as dual selective estrogen receptor modulators (SERMs) and antiangiogenic agents

European journal of medicinal chemistry, 2017-10, Vol.139, p.390-400

2017

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Design, synthesis and biological evaluation of novel 3-oxo-4-oxa-5α-androst-17β-amide derivatives as dual 5α-reductase inhibitors and androgen receptor antagonists

Bioorganic & medicinal chemistry letters, 2017-09, Vol.27 (17), p.4212-4217

2017

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Aerobic exercise‑stimulated Klotho upregulation extends life span by attenuating the excess production of reactive oxygen species in the brain and kidney

Experimental and therapeutic medicine, 2018-10

2018

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Aerobic exercise promotes the expression of ERCC1 to prolong lifespan: A new possible mechanism

Medical hypotheses, 2019-01, Vol.122, p.22-25

2019

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Stability and inhibitory function of Treg cells under inflammatory conditions in vitro

Experimental and therapeutic medicine, 2019-10

2019

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Design, synthesis and evaluation of 6-aryl-indenoisoquinolone derivatives dual targeting ERα and VEGFR-2 as anti-breast cancer agents

European journal of medicinal chemistry, 2016-08, Vol.118, p.328-339

2016

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Design, synthesis and biological evaluation of novel androst-3,5-diene-3-carboxylic acid derivatives as inhibitors of 5α-reductase type 1 and 2

Steroids, 2017-08, Vol.124, p.29-34

2017

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3, 9-di-O-substituted coumestrols incorporating basic amine side chains act as novel apoptosis inducers with improved pharmacological selectivity

Bioorganic chemistry, 2019-04, Vol.85, p.140-151

2019

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Synthesis and biological evaluation of 2,3-diaryl isoquinolinone derivatives as anti-breast cancer agents targeting ERα and VEGFR-2

Bioorganic & medicinal chemistry letters, 2014-05, Vol.24 (9), p.2129-2133

2014

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Amyloid-beta Targeted Therapeutic Approaches for Alzheimer’s Disease: Long Road Ahead

Design, synthesis, and biological evaluation of novel androst-17β-amide structurally related compounds as dual 5α-reductase inhibitors and androgen receptor antagonists

Therapeutic Strategies Targeting Amyloid-β Receptors and Transporters in Alzheimer’s Disease

Drug development for Alzheimer's disease: review

Gpn2 and Rba50 Directly Participate in the Assembly of the Rpb3 Subcomplex in the Biogenesis of RNA Polymerase II

Structure-activity relationships of 2, 4-disubstituted pyrimidines as dual ERα/VEGFR-2 ligands with anti-breast cancer activity

AMPK alleviates oxidative stress‑induced premature senescence via inhibition of NF-κB/STAT3 axis-mediated positive feedback loop

Identification of novel Aβ-LilrB2 inhibitors as potential therapeutic agents for Alzheimer's disease

Rapid and highly specific detection of site-specific 5-hydroxymethylcytosine based on peroxotungstate oxidation and mismatch ligation-based LAMP

(m)RVD-hemopressin (α) and (m)VD-hemopressin (α) improve the memory-impairing effect of scopolamine in novel object and object location recognition tasks in mice

Design and synthesis of novel steroidal imidazoles as dual inhibitors of AR/CYP17 for the treatment of prostate cancer

Potential Astrocytic Receptors and Transporters in the Pathogenesis of Alzheimer's Disease

Effect of (m)VD-hemopressin against Aβ1-42-induced oxidative stress and apoptosis in mouse hippocampal neurons

Design, synthesis and biological evaluation of novel 2-methoxyestradiol analogs as dual selective estrogen receptor modulators (SERMs) and antiangiogenic agents

Design, synthesis and biological evaluation of novel 3-oxo-4-oxa-5α-androst-17β-amide derivatives as dual 5α-reductase inhibitors and androgen receptor antagonists

Aerobic exercise‑stimulated Klotho upregulation extends life span by attenuating the excess production of reactive oxygen species in the brain and kidney

Aerobic exercise promotes the expression of ERCC1 to prolong lifespan: A new possible mechanism

Stability and inhibitory function of Treg cells under inflammatory conditions in vitro

Design, synthesis and evaluation of 6-aryl-indenoisoquinolone derivatives dual targeting ERα and VEGFR-2 as anti-breast cancer agents

Design, synthesis and biological evaluation of novel androst-3,5-diene-3-carboxylic acid derivatives as inhibitors of 5α-reductase type 1 and 2

3, 9-di-O-substituted coumestrols incorporating basic amine side chains act as novel apoptosis inducers with improved pharmacological selectivity

Synthesis and biological evaluation of 2,3-diaryl isoquinolinone derivatives as anti-breast cancer agents targeting ERα and VEGFR-2

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