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Indolo-Phakellins as β5-Specific Noncovalent Proteasome Inhibitors

Angewandte Chemie (International ed.), 2015-02, Vol.54 (9), p.2830-2833

2015

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Characterization of the Biosynthetic Operon for the Antibacterial Peptide Herbicolin in Pantoea vagans Biocontrol Strain C9-1 and Incidence in Pantoea Species

Applied and Environmental Microbiology, 2012-06, Vol.78 (12), p.4412-4419

2012

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Palau’amine and Related Oroidin Alkaloids Dibromophakellin and Dibromophakellstatin Inhibit the Human 20S Proteasome

Journal of natural products (Washington, D.C.), 2012-05, Vol.75 (5), p.980-985

2012

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Chronic cerebral hypoperfusion in male rats results in sustained HPA activation and hyperinsulinemia

American journal of physiology: endocrinology and metabolism, 2022-01, Vol.322 (1), p.E24-E33

2022

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Small Molecule 20S Proteasome Enhancer Regulates MYC Protein Stability and Exhibits Antitumor Activity in Multiple Myeloma

Biomedicines, 2022-04, Vol.10 (5), p.938

2022

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Inhibition of Cytokine Production by Hymenialdisine Derivatives

Journal of medicinal chemistry, 2004-07, Vol.47 (14), p.3700-3703

2004

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Soluble epoxide hydrolase inhibition improves cognitive function and parenchymal artery dilation in a hypertensive model of chronic cerebral hypoperfusion

Microcirculation (New York, N.Y. 1994), 2021-01, Vol.28 (1), p.e12653-n/a

2021

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The effects of gestational and chronic atrazine exposure on motor behaviors and striatal dopamine in male Sprague-Dawley rats

Toxicology and applied pharmacology, 2015-12, Vol.289 (2), p.185-192

2015

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Indolo-Phakellins as beta 5-Specific Noncovalent Proteasome Inhibitors

Angewandte Chemie International Edition, 2015-02, Vol.54 (9), p.2830-2833

2015

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Substituted quinolines as noncovalent proteasome inhibitors

Bioorganic & medicinal chemistry, 2016-06, Vol.24 (11), p.2441-2450

2016

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Inhibition of the Human Proteasome by Imidazoline Scaffolds

Journal of medicinal chemistry, 2013-07, Vol.56 (14), p.5974-5978

2013

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Synthesis and evaluation of debromohymenialdisine-derived Chk2 inhibitors

Bioorganic & medicinal chemistry, 2012-02, Vol.20 (4), p.1475-1481

2012

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Rs10230207 genotype confers changes in HDAC9 and TWIST1, but not FERD3L in lymphoblasts from patients with intracranial aneurysm

Neurogenetics, 2019-05, Vol.20 (2), p.83-89

2019

Volltextzugriff (PDF)

Noncompetitive Modulation of the Proteasome by Imidazoline Scaffolds Overcomes Bortezomib Resistance and Delays MM Tumor Growth in Vivo

ACS chemical biology, 2013-03, Vol.8 (3), p.578-587

2013

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Structural–activity relationship study of highly-functionalized imidazolines as potent inhibitors of nuclear transcription factor-κB mediated IL-6 production

Bioorganic & medicinal chemistry, 2009-04, Vol.17 (8), p.3093-3103

2009

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Nuclear Factor-κB Mediated Inhibition of Cytokine Production by Imidazoline Scaffolds

Journal of medicinal chemistry, 2009-03, Vol.52 (5), p.1302-1309

2009

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Attenuation of collagen-induced arthritis by orally available imidazoline-based NF-κB inhibitors

Bioorganic & medicinal chemistry letters, 2012-07, Vol.22 (14), p.4816-4819

2012

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Endothelial Cells and the Cerebral Circulation

Comprehensive Physiology, 2022-06, Vol.12 (3), p.3449-3508

2022

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Glucocorticoid excess and insulin resistance in rat models of vascular contributions to cognitive impairment and dementia

Alzheimer's & dementia, 2023-12, Vol.19 (S12), p.n/a

2023

Volltextzugriff (PDF)

Increased HDAC9 Expression is Associated with Decreased Estrogen in Female Patients with Intracranial Aneurysm

The FASEB journal, 2019-04, Vol.33 (S1), p.828.5-828.5

2019

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Indolo-Phakellins as [beta]5-Specific Noncovalent Proteasome Inhibitors

Angewandte Chemie International Edition, 2015-02, Vol.54 (9), p.2830

International ed. in English, 2015

Volltextzugriff (PDF)

Abstract 2777: Suppression of multiple myeloma via non-canonical inhibition of NF-κB

Cancer research (Chicago, Ill.), 2012-04, Vol.72 (8_Supplement), p.2777-2777

2012

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The Role of Parkin in Maintaining Proteasome Activity Following Acute Neurotoxic Insult

Lansdell, Theresa A

2017

Volltextzugriff (PDF)

Non-competitive modulation of the proteasome by imidazoline scaffolds overcome bortezomib resistant and delay MM tumor growth in vivo

ACS chemical biology, 2012-12, Vol.8 (3), p.578-587

2012

Volltextzugriff (PDF)

Attenuation of collagen-induced arthritis by orally available imidazoline-based NF-KB inhibitors

Bioorganic & medicinal chemistry letters, 2012, Vol.22 (14), p.4816-4819

2012

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Indolo-Phakellins as β5-Specific Noncovalent Proteasome Inhibitors

Characterization of the Biosynthetic Operon for the Antibacterial Peptide Herbicolin in Pantoea vagans Biocontrol Strain C9-1 and Incidence in Pantoea Species

Palau’amine and Related Oroidin Alkaloids Dibromophakellin and Dibromophakellstatin Inhibit the Human 20S Proteasome

Chronic cerebral hypoperfusion in male rats results in sustained HPA activation and hyperinsulinemia

Small Molecule 20S Proteasome Enhancer Regulates MYC Protein Stability and Exhibits Antitumor Activity in Multiple Myeloma

Inhibition of Cytokine Production by Hymenialdisine Derivatives

Soluble epoxide hydrolase inhibition improves cognitive function and parenchymal artery dilation in a hypertensive model of chronic cerebral hypoperfusion

The effects of gestational and chronic atrazine exposure on motor behaviors and striatal dopamine in male Sprague-Dawley rats

Indolo-Phakellins as beta 5-Specific Noncovalent Proteasome Inhibitors

Substituted quinolines as noncovalent proteasome inhibitors

Inhibition of the Human Proteasome by Imidazoline Scaffolds

Synthesis and evaluation of debromohymenialdisine-derived Chk2 inhibitors

Rs10230207 genotype confers changes in HDAC9 and TWIST1, but not FERD3L in lymphoblasts from patients with intracranial aneurysm

Noncompetitive Modulation of the Proteasome by Imidazoline Scaffolds Overcomes Bortezomib Resistance and Delays MM Tumor Growth in Vivo

Structural–activity relationship study of highly-functionalized imidazolines as potent inhibitors of nuclear transcription factor-κB mediated IL-6 production

Nuclear Factor-κB Mediated Inhibition of Cytokine Production by Imidazoline Scaffolds

Attenuation of collagen-induced arthritis by orally available imidazoline-based NF-κB inhibitors

Endothelial Cells and the Cerebral Circulation

Glucocorticoid excess and insulin resistance in rat models of vascular contributions to cognitive impairment and dementia

Increased HDAC9 Expression is Associated with Decreased Estrogen in Female Patients with Intracranial Aneurysm

Indolo-Phakellins as [beta]5-Specific Noncovalent Proteasome Inhibitors

Abstract 2777: Suppression of multiple myeloma via non-canonical inhibition of NF-κB

The Role of Parkin in Maintaining Proteasome Activity Following Acute Neurotoxic Insult

Non-competitive modulation of the proteasome by imidazoline scaffolds overcome bortezomib resistant and delay MM tumor growth in vivo

Attenuation of collagen-induced arthritis by orally available imidazoline-based NF-KB inhibitors

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