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Minority HIV-1 drug resistance mutations are present in antiretroviral treatment-naïve populations and associate with reduced treatment efficacy

PLoS medicine, 2008-07, Vol.5 (7), p.e158-e158

2008

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CMX001 Potentiates the Efficacy of Acyclovir in Herpes Simplex Virus Infections

Antimicrobial Agents and Chemotherapy, 2011-10, Vol.55 (10), p.4728-4734

2011

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Selection and Recombinant Phenotyping of a Novel CMX001 and Cidofovir Resistance Mutation in Human Cytomegalovirus

Antimicrobial Agents and Chemotherapy, 2013-07, Vol.57 (7), p.3321-3325

2013

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Analysis of Mutations in the Gene Encoding Cytomegalovirus DNA Polymerase in a Phase 2 Clinical Trial of Brincidofovir Prophylaxis

The Journal of infectious diseases, 2016-07, Vol.214 (1), p.32-35

2016

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Abacavir versus Zidovudine Combined with Lamivudine and Efavirenz, for the Treatment of Antiretroviral-Naive HIV-Infected Adults

Clinical infectious diseases, 2004-10, Vol.39 (7), p.1038-1046

2004

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Development of Hexadecyloxypropyl Tenofovir (CMX157) for Treatment of Infection Caused by Wild-Type and Nucleoside/Nucleotide-Resistant HIV

Antimicrobial Agents and Chemotherapy, 2010-07, Vol.54 (7), p.2901-2909

2010

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Novel Cytomegalovirus UL54 DNA Polymerase Gene Mutations Selected In Vitro That Confer Brincidofovir Resistance

Antimicrobial agents and chemotherapy, 2016-06, Vol.60 (6), p.3845-3848

2016

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In vitro efficacy of brincidofovir against variola virus

Antimicrobial agents and chemotherapy, 2014-09, Vol.58 (9), p.5570-5571

2014

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The lipid moiety of brincidofovir is required for in vitro antiviral activity against Ebola virus

Antiviral research, 2016-01, Vol.125, p.71-78

2016

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Relative anti-HIV-1 efficacy of lamivudine and emtricitabine in vitro is dependent on cell type

Journal of acquired immune deficiency syndromes (1999), 2003-03, Vol.32 (3), p.255-258

2003

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Eradication of disseminated adenovirus infection in a pediatric hematopoietic stem cell transplantation recipient using the novel antiviral agent CMX001

Journal of clinical virology, 2011-02, Vol.50 (2), p.167-170

2011

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Co-administration of the broad-spectrum antiviral, brincidofovir (CMX001), with smallpox vaccine does not compromise vaccine protection in mice challenged with ectromelia virus

Antiviral research, 2014-11, Vol.111, p.42-52

2014

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Antiviral Activity of Lamivudine in Salvage Therapy for Multidrug-Resistant HIV-1 Infection

Clinical infectious diseases, 2005-07, Vol.41 (2), p.236-242

2005

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Minimizing resistance consequences after virologic failure on initial combination therapy: a systematic overview

Journal of acquired immune deficiency syndromes (1999), 2006-03, Vol.41 (3), p.323-331

2006

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Induction with abacavir/lamivudine/zidovudine plus efavirenz for 48 weeks followed by 48-week maintenance with abacavir/lamivudine/zidovudine alone in antiretroviral-naive HIV-1-infected patients

Journal of acquired immune deficiency syndromes (1999), 2005-07, Vol.39 (3), p.257-264

2005

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The addition of mycophenolate mofetil to antiretroviral therapy including abacavir is associated with depletion of intracellular deoxyguanosine triphosphate and a decrease in plasma HIV-1 RNA

Journal of acquired immune deficiency syndromes (1999), 2002-09, Vol.31 (1), p.45-49

2002

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Sensitivity of Phenotypic Susceptibility Analyses for Nonthymidine Nucleoside Analogues Conferred by K65R or M184V in Mixtures with Wild-Type HIV-1

The Journal of infectious diseases, 2009-01, Vol.199 (1), p.84-88

2009

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Cerebrospinal Fluid β Chemokine Concentrations in Neurocognitively Impaired Individuals Infected with Human Immunodeficiency Virus Type 1

The Journal of infectious diseases, 1999-08, Vol.180 (2), p.310-319

1999

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Diminished selection for thymidine-analog mutations associated with the presence of M184V in Ethiopian children infected with HIV subtype C receiving lamivudine-containing therapy

The Pediatric infectious disease journal, 2006-11, Vol.25 (11), p.1049-1056

2006

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Effect of combination antiretroviral therapy on cerebrospinal fluid HIV RNA, HIV resistance, and clinical manifestations of encephalopathy

The Journal of pediatrics, 2002-07, Vol.141 (1), p.36-44

2002

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Antiviral efficacy of abacavir in antiretroviral therapy-experienced adults harbouring HIV-1 with specific patterns of resistance to nucleoside reverse transcriptase inhibitors

Antiviral therapy, 2004-02, Vol.9 (1), p.37-45

2004

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Lack of antagonism between abacavir, lamivudine, and tenofovir against wild-type and drug-resistant HIV-1

Journal of acquired immune deficiency syndromes (1999), 2005-08, Vol.39 (5), p.519

2005

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Cerebrospinal fluid and plasma concentrations of proinflammatory mediators in human immunodeficiency virus-infected children

The Pediatric infectious disease journal, 2004-02, Vol.23 (2), p.114-118

2004

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Salvage therapy with abacavir and other reverse transcriptase inhibitors for human immunodeficiency-associated encephalopathy

The Pediatric infectious disease journal, 2006-12, Vol.25 (12), p.1142-1152

2006

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Binding of Thymic Factors to the Conserved Decanucleotide Promoter Element of the T-Cell Receptor VβGene is Developmentally Regulated and is Absent in SCID Mice

Proceedings of the National Academy of Sciences - PNAS, 1991-09, Vol.88 (18), p.8131-8135

1991

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Minority HIV-1 drug resistance mutations are present in antiretroviral treatment-naïve populations and associate with reduced treatment efficacy

CMX001 Potentiates the Efficacy of Acyclovir in Herpes Simplex Virus Infections

Selection and Recombinant Phenotyping of a Novel CMX001 and Cidofovir Resistance Mutation in Human Cytomegalovirus

Analysis of Mutations in the Gene Encoding Cytomegalovirus DNA Polymerase in a Phase 2 Clinical Trial of Brincidofovir Prophylaxis

Abacavir versus Zidovudine Combined with Lamivudine and Efavirenz, for the Treatment of Antiretroviral-Naive HIV-Infected Adults

Development of Hexadecyloxypropyl Tenofovir (CMX157) for Treatment of Infection Caused by Wild-Type and Nucleoside/Nucleotide-Resistant HIV

Novel Cytomegalovirus UL54 DNA Polymerase Gene Mutations Selected In Vitro That Confer Brincidofovir Resistance

In vitro efficacy of brincidofovir against variola virus

The lipid moiety of brincidofovir is required for in vitro antiviral activity against Ebola virus

Relative anti-HIV-1 efficacy of lamivudine and emtricitabine in vitro is dependent on cell type

Eradication of disseminated adenovirus infection in a pediatric hematopoietic stem cell transplantation recipient using the novel antiviral agent CMX001

Co-administration of the broad-spectrum antiviral, brincidofovir (CMX001), with smallpox vaccine does not compromise vaccine protection in mice challenged with ectromelia virus

Antiviral Activity of Lamivudine in Salvage Therapy for Multidrug-Resistant HIV-1 Infection

Minimizing resistance consequences after virologic failure on initial combination therapy: a systematic overview

Induction with abacavir/lamivudine/zidovudine plus efavirenz for 48 weeks followed by 48-week maintenance with abacavir/lamivudine/zidovudine alone in antiretroviral-naive HIV-1-infected patients

The addition of mycophenolate mofetil to antiretroviral therapy including abacavir is associated with depletion of intracellular deoxyguanosine triphosphate and a decrease in plasma HIV-1 RNA

Sensitivity of Phenotypic Susceptibility Analyses for Nonthymidine Nucleoside Analogues Conferred by K65R or M184V in Mixtures with Wild-Type HIV-1

Cerebrospinal Fluid β Chemokine Concentrations in Neurocognitively Impaired Individuals Infected with Human Immunodeficiency Virus Type 1

Diminished selection for thymidine-analog mutations associated with the presence of M184V in Ethiopian children infected with HIV subtype C receiving lamivudine-containing therapy

Effect of combination antiretroviral therapy on cerebrospinal fluid HIV RNA, HIV resistance, and clinical manifestations of encephalopathy

Antiviral efficacy of abacavir in antiretroviral therapy-experienced adults harbouring HIV-1 with specific patterns of resistance to nucleoside reverse transcriptase inhibitors

Lack of antagonism between abacavir, lamivudine, and tenofovir against wild-type and drug-resistant HIV-1

Cerebrospinal fluid and plasma concentrations of proinflammatory mediators in human immunodeficiency virus-infected children

Salvage therapy with abacavir and other reverse transcriptase inhibitors for human immunodeficiency-associated encephalopathy

Binding of Thymic Factors to the Conserved Decanucleotide Promoter Element of the T-Cell Receptor VβGene is Developmentally Regulated and is Absent in SCID Mice

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