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Monoclonal Antibodies Follow Distinct Aggregation Pathways During Production-Relevant Acidic Incubation and Neutralization

Pharmaceutical research, 2016-03, Vol.33 (3), p.716-728

2016

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The impact of folding modes and deuteration on the atomic resolution structure of hen egg‐white lysozyme

Acta crystallographica. Section D, Biological crystallography., 2021-12, Vol.77 (12), p.1579-1590

2021

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The structural basis of fungal glucuronoyl esterase activity on natural substrates

Nature communications, 2020-02, Vol.11 (1), p.1026-12, Article 1026

2020

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The architecture of amyloid-like peptide fibrils revealed by X-ray scattering, diffraction and electron microscopy

Acta crystallographica. Section D, Biological crystallography., 2015-04, Vol.71 (4), p.882-895

2015

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Small-Angle X-ray Scattering Screening Complements Conventional Biophysical Analysis: Comparative Structural and Biophysical Analysis of Monoclonal Antibodies IgG1, IgG2, and IgG4

Journal of pharmaceutical sciences, 2014-06, Vol.103 (6), p.1701-1710

2014

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Refinement of α-Synuclein Ensembles Against SAXS Data: Comparison of Force Fields and Methods

Frontiers in molecular biosciences, 2021-04, Vol.8, p.654333-654333

2021

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Sex-dependent neuronal effects of α-synuclein reveal that GABAergic transmission is neuroprotective of sleep-controlling neurons

Cell & bioscience, 2023-09, Vol.13 (1), p.1-172, Article 172

2023

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Insight into Calcium-Binding Motifs of Intrinsically Disordered Proteins

Biomolecules (Basel, Switzerland), 2021-08, Vol.11 (8), p.1173

2021

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Structural insights into protein folding, stability and activity using in vivo perdeuteration of hen egg-white lysozyme

IUCrJ, 2021-05, Vol.8 (Pt 3), p.372-386

2021

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In-depth analysis of subclass-specific conformational preferences of IgG antibodies

IUCrJ, 2015-01, Vol.2 (Pt 1), p.9-18

2015

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Sex-dependent effects of monomeric α-synuclein on calcium and cell death of lateral hypothalamic mouse neurons are altered by orexin

Molecular and cellular neuroscience, 2024-06, Vol.129, p.103934, Article 103934

2024

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Distinct α‑Synuclein:Lipid Co-Structure Complexes Affect Amyloid Nucleation through Fibril Mimetic Behavior

Biochemistry (Easton), 2019-12, Vol.58 (50), p.5052-5065

2019

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Size-Selective Phagocytic Clearance of Fibrillar α-Synuclein through Conformational Activation of Complement Receptor 4

The Journal of immunology (1950), 2020-03, Vol.204 (5), p.1345-1361

2020

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Sleep-controlling neurons are sensitive and vulnerable to multiple forms of α-synuclein: implications for the early appearance of sleeping disorders in α-synucleinopathies

Cellular and molecular life sciences : CMLS, 2022-08, Vol.79 (8), p.450-450, Article 450

2022

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Femtosecond X-ray coherent diffraction of aligned amyloid fibrils on low background graphene

Nature communications, 2018-05, Vol.9 (1), p.1836-10, Article 1836

2018

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Sex-dependent neuronal effects of [alpha]-synuclein reveal that GABAergic transmission is neuroprotective of sleep-controlling neurons

Cell & bioscience, 2023-09, Vol.13 (1)

2023

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α-Synuclein Responses in the Laterodorsal Tegmentum, the Pedunculopontine Tegmentum, and the Substantia Nigra: Implications for Early Appearance of Sleep Disorders in Parkinson's Disease

Journal of Parkinson's disease, 2021-01, Vol.11 (4), p.1773

2021

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Recommendations for addressing the translational gap between experimental and clinical research on amyloid diseases

Journal of translational medicine, 2022-05, Vol.20 (1), p.213-213, Article 213

2022

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Insight into calcium-binding motifs of intrinsically disordered proteins

Biophysical journal, 2022-02, Vol.121 (3), p.300a-300a

2022

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Refinement of [ALPHA]-Synuclein Ensembles Against SAXS Data: Comparison of Force Fields and Methods

Frontiers in molecular biosciences, 2021-04

2021

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Methods for structural characterization of prefibrillar intermediates and amyloid fibrils

FEBS letters, 2009-08, Vol.583 (16), p.2600-2609

2009

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Structural and Functional Insight into How the Plasmodium falciparum VAR2CSA Protein Mediates Binding to Chondroitin Sulfate A in Placental Malaria

The Journal of biological chemistry, 2012-07, Vol.287 (28), p.23332-23345

2012

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Monoclonal Antibodies Follow Distinct Aggregation Pathways During Production-Relevant Acidic Incubation and Neutralization

The impact of folding modes and deuteration on the atomic resolution structure of hen egg‐white lysozyme

The structural basis of fungal glucuronoyl esterase activity on natural substrates

The architecture of amyloid-like peptide fibrils revealed by X-ray scattering, diffraction and electron microscopy

Small-Angle X-ray Scattering Screening Complements Conventional Biophysical Analysis: Comparative Structural and Biophysical Analysis of Monoclonal Antibodies IgG1, IgG2, and IgG4

Refinement of α-Synuclein Ensembles Against SAXS Data: Comparison of Force Fields and Methods

Sex-dependent neuronal effects of α-synuclein reveal that GABAergic transmission is neuroprotective of sleep-controlling neurons

Insight into Calcium-Binding Motifs of Intrinsically Disordered Proteins

Structural insights into protein folding, stability and activity using in vivo perdeuteration of hen egg-white lysozyme

In-depth analysis of subclass-specific conformational preferences of IgG antibodies

Sex-dependent effects of monomeric α-synuclein on calcium and cell death of lateral hypothalamic mouse neurons are altered by orexin

Distinct α‑Synuclein:Lipid Co-Structure Complexes Affect Amyloid Nucleation through Fibril Mimetic Behavior

Size-Selective Phagocytic Clearance of Fibrillar α-Synuclein through Conformational Activation of Complement Receptor 4

Sleep-controlling neurons are sensitive and vulnerable to multiple forms of α-synuclein: implications for the early appearance of sleeping disorders in α-synucleinopathies

Femtosecond X-ray coherent diffraction of aligned amyloid fibrils on low background graphene

Sex-dependent neuronal effects of [alpha]-synuclein reveal that GABAergic transmission is neuroprotective of sleep-controlling neurons

α-Synuclein Responses in the Laterodorsal Tegmentum, the Pedunculopontine Tegmentum, and the Substantia Nigra: Implications for Early Appearance of Sleep Disorders in Parkinson's Disease

Recommendations for addressing the translational gap between experimental and clinical research on amyloid diseases

Insight into calcium-binding motifs of intrinsically disordered proteins

Refinement of [ALPHA]-Synuclein Ensembles Against SAXS Data: Comparison of Force Fields and Methods

Methods for structural characterization of prefibrillar intermediates and amyloid fibrils

Structural and Functional Insight into How the Plasmodium falciparum VAR2CSA Protein Mediates Binding to Chondroitin Sulfate A in Placental Malaria

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