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Targeting Cysteine Located Outside the Active Site: An Effective Strategy for Covalent ALKi Design

Journal of medicinal chemistry, 2021-02, Vol.64 (3), p.1558-1569

2021

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Low Toxicity of Metal-Organic Framework MOF-74(Co) Nano-Particles In Vitro and In Vivo

Nanomaterials (Basel, Switzerland), 2022-09, Vol.12 (19), p.3398

2022

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Surface modification mediates the interaction between fullerene and lysozyme: protein structure and antibacterial activity

Environmental science. Nano, 2021-01, Vol.8 (1), p.76-85

2021

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Fast Identification and Quantification of Graphene Oxide in Aqueous Environment by Raman Spectroscopy

Nanomaterials (Basel, Switzerland), 2020-04, Vol.10 (4), p.770

2020

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Synthesis and biological evaluation of 3-(1,3,4-oxadiazol-2-yl)-1,8-naphthyridin-4(1 H )-ones as cisplatin sensitizers

MedChemComm, 2018-11, Vol.9 (11), p.1949-1960

2018

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Toxicity and photosynthetic inhibition of metal-organic framework MOF-199 to pea seedlings

Journal of hazardous materials, 2021-05, Vol.409, p.124521-124521, Article 124521

2021

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Discovery of a PROTAC targeting ALK with in vivo activity

European journal of medicinal chemistry, 2021-02, Vol.212, p.113150, Article 113150

2021

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Modification of metal–organic frameworks Zn(BDC) with 8-hydroquinoline and their application in lymph node imaging in vivo

Materials letters, 2023-11, Vol.350, p.134890, Article 134890

2023

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Magnetic Fe3O4/TiO2/graphene sponge for the adsorption of methylene blue in aqueous solution

Diamond and related materials, 2022-03, Vol.123, p.108811, Article 108811

2022

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Discovery of 2‑Methyl-2-(4-(2-methyl-8-(1H‑pyrrolo[2,3‑b]pyridin-6-yl)‑1H‑naphtho[1,2‑d]imidazol-1-yl)phenyl)propanenitrile as a Novel PI3K/mTOR Inhibitor with Enhanced Antitumor Efficacy In Vitro and In Vivo

Journal of medicinal chemistry, 2022-10, Vol.65 (19), p.12781-12801

2022

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Selective degradation of PARP2 by PROTACs via recruiting DCAF16 for triple-negative breast cancer

European journal of medicinal chemistry, 2022-06, Vol.236, p.114321-114321, Article 114321

2022

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Discovery of 2-Methyl-2-(4-(2-methyl-8-(1 H -pyrrolo[2,3- b ]pyridin-6-yl)-1 H -naphtho[1,2- d ]imidazol-1-yl)phenyl)propanenitrile as a Novel PI3K/mTOR Inhibitor with Enhanced Antitumor Efficacy In Vitro and In Vivo

Journal of medicinal chemistry, 2022-10, Vol.65 (19), p.12781-12801

2022

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Synthesis and biological evaluation of a tumor-selective degrader of PARP1

Bioorganic & medicinal chemistry, 2022-09, Vol.69, p.116908-116908, Article 116908

2022

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Discovery of (R)-4-(8-methoxy-2-methyl-1-(1-phenylethy)-1H-imidazo[4,5-c]quinnolin-7-yl)-3,5-dimethylisoxazole as a potent and selective BET inhibitor for treatment of acute myeloid leukemia (AML) guided by FEP calculation

European journal of medicinal chemistry, 2024-01, Vol.263, p.115924-115924, Article 115924

2024

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Discovery of a novel covalent CDK4/6 inhibitor based on palbociclib scaffold

European journal of medicinal chemistry, 2021-07, Vol.219, p.113432-113432, Article 113432

2021

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Discovery of 4-phenyl-2H-benzo[b][1,4]oxazin-3(4H)-one derivatives as potent and orally active PI3K/mTOR dual inhibitors

European journal of medicinal chemistry, 2019-09, Vol.178, p.667-686

2019

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Biocompatible zinc gallogermanate persistent luminescent nanoparticles for fast tumor drainage lymph node imaging in vivo

Colloids and surfaces, B, Biointerfaces, 2021-09, Vol.205, p.111887-111887, Article 111887

2021

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Discovery of 4-(3,5-dimethoxy-4-(((4-methoxyphenethyl)amino)methyl)phenoxy)-N-phenylaniline as a novel c-myc inhibitor against colorectal cancer in vitro and in vivo

European journal of medicinal chemistry, 2020-07, Vol.198, p.112336, Article 112336

2020

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Low toxicity of fluorescent carbon quantum dots to white rot fungus Phanerochaete chrysosporium

Journal of environmental chemical engineering, 2021-02, Vol.9 (1), p.104633, Article 104633

2021

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Carbonization reduces the toxicity of metal-organic framework MOF-199 to white-rot fungus Phanerochaete chrysosporium

Journal of environmental chemical engineering, 2021-12, Vol.9 (6), p.106705, Article 106705

2021

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Pharmacophore‐based virtual screening, molecular docking, molecular dynamics simulation, and biological evaluation for the discovery of novel BRD4 inhibitors

Chemical biology & drug design, 2018-02, Vol.91 (2), p.478-490

2018

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Pharmacophore‐based virtual screening, molecular docking, molecular dynamics simulation, and biological evaluation for the discovery of novel BRD 4 inhibitors

Chemical biology & drug design, 2018-02, Vol.91 (2), p.478-490

2018

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Low toxicity of metal-organic framework MOF-199 to bacteria Escherichia coli and Staphylococcus aureus

Journal of hazardous materials advances, 2021-09, Vol.1, p.100002, Article 100002

2021

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Synthesis and biological evaluation of 3-(1,3,4-oxadiazol-2-yl)-1,8-naphthyridin-4(1H)-ones as cisplatin sensitizersElectronic supplementary information (ESI) available. See DOI: 10.1039/c8md00464a

2018-11

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Synthesis and biological evaluation of 3-(1,3,4-oxadiazol-2-yl)-1,8-naphthyridin-4(1H)-ones as cisplatin sensitizers† †Electronic supplementary information (ESI) available. See DOI: 10.1039/c8md00464a

MedChemComm, 2018-09, Vol.9 (11), p.1949-1960

2018

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Targeting Cysteine Located Outside the Active Site: An Effective Strategy for Covalent ALKi Design

Low Toxicity of Metal-Organic Framework MOF-74(Co) Nano-Particles In Vitro and In Vivo

Surface modification mediates the interaction between fullerene and lysozyme: protein structure and antibacterial activity

Fast Identification and Quantification of Graphene Oxide in Aqueous Environment by Raman Spectroscopy

Synthesis and biological evaluation of 3-(1,3,4-oxadiazol-2-yl)-1,8-naphthyridin-4(1 H )-ones as cisplatin sensitizers

Toxicity and photosynthetic inhibition of metal-organic framework MOF-199 to pea seedlings

Discovery of a PROTAC targeting ALK with in vivo activity

Modification of metal–organic frameworks Zn(BDC) with 8-hydroquinoline and their application in lymph node imaging in vivo

Magnetic Fe3O4/TiO2/graphene sponge for the adsorption of methylene blue in aqueous solution

Discovery of 2‑Methyl-2-(4-(2-methyl-8-(1H‑pyrrolo[2,3‑b]pyridin-6-yl)‑1H‑naphtho[1,2‑d]imidazol-1-yl)phenyl)propanenitrile as a Novel PI3K/mTOR Inhibitor with Enhanced Antitumor Efficacy In Vitro and In Vivo

Selective degradation of PARP2 by PROTACs via recruiting DCAF16 for triple-negative breast cancer

Discovery of 2-Methyl-2-(4-(2-methyl-8-(1 H -pyrrolo[2,3- b ]pyridin-6-yl)-1 H -naphtho[1,2- d ]imidazol-1-yl)phenyl)propanenitrile as a Novel PI3K/mTOR Inhibitor with Enhanced Antitumor Efficacy In Vitro and In Vivo

Synthesis and biological evaluation of a tumor-selective degrader of PARP1

Discovery of (R)-4-(8-methoxy-2-methyl-1-(1-phenylethy)-1H-imidazo[4,5-c]quinnolin-7-yl)-3,5-dimethylisoxazole as a potent and selective BET inhibitor for treatment of acute myeloid leukemia (AML) guided by FEP calculation

Discovery of a novel covalent CDK4/6 inhibitor based on palbociclib scaffold

Discovery of 4-phenyl-2H-benzo[b][1,4]oxazin-3(4H)-one derivatives as potent and orally active PI3K/mTOR dual inhibitors

Biocompatible zinc gallogermanate persistent luminescent nanoparticles for fast tumor drainage lymph node imaging in vivo

Discovery of 4-(3,5-dimethoxy-4-(((4-methoxyphenethyl)amino)methyl)phenoxy)-N-phenylaniline as a novel c-myc inhibitor against colorectal cancer in vitro and in vivo

Low toxicity of fluorescent carbon quantum dots to white rot fungus Phanerochaete chrysosporium

Carbonization reduces the toxicity of metal-organic framework MOF-199 to white-rot fungus Phanerochaete chrysosporium

Pharmacophore‐based virtual screening, molecular docking, molecular dynamics simulation, and biological evaluation for the discovery of novel BRD4 inhibitors

Pharmacophore‐based virtual screening, molecular docking, molecular dynamics simulation, and biological evaluation for the discovery of novel BRD 4 inhibitors

Low toxicity of metal-organic framework MOF-199 to bacteria Escherichia coli and Staphylococcus aureus

Synthesis and biological evaluation of 3-(1,3,4-oxadiazol-2-yl)-1,8-naphthyridin-4(1H)-ones as cisplatin sensitizersElectronic supplementary information (ESI) available. See DOI: 10.1039/c8md00464a

Synthesis and biological evaluation of 3-(1,3,4-oxadiazol-2-yl)-1,8-naphthyridin-4(1H)-ones as cisplatin sensitizers† †Electronic supplementary information (ESI) available. See DOI: 10.1039/c8md00464a

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