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Fusion mechanism of 2019-nCoV and fusion inhibitors targeting HR1 domain in spike protein

Cellular & molecular immunology, 2020-07, Vol.17 (7), p.765-767

2020

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The role of furin cleavage site in SARS-CoV-2 spike protein-mediated membrane fusion in the presence or absence of trypsin

Signal transduction and targeted therapy, 2020-06, Vol.5 (1), p.92, Article 92

2020

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Inhibition of SARS-CoV-2 (previously 2019-nCoV) infection by a highly potent pan-coronavirus fusion inhibitor targeting its spike protein that harbors a high capacity to mediate membrane fusion

Cell research, 2020-04, Vol.30 (4), p.343-355

2020

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Pan‐coronavirus fusion inhibitors to combat COVID‐19 and other emerging coronavirus infectious diseases

Journal of medical virology, 2023-01, Vol.95 (1), p.e28143-n/a

2023

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Development of oncolytic virotherapy: from genetic modification to combination therapy

Frontiers of medicine, 2020-04, Vol.14 (2), p.160-184

2020

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Peptide-based pan-CoV fusion inhibitors maintain high potency against SARS-CoV-2 Omicron variant

Cell research, 2022-04, Vol.32 (4), p.404-406

2022

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25-Hydroxycholesterol-Conjugated EK1 Peptide with Potent and Broad-Spectrum Inhibitory Activity against SARS-CoV-2, Its Variants of Concern, and Other Human Coronaviruses

International journal of molecular sciences, 2021-11, Vol.22 (21), p.11869

2021

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Structural and functional basis for pan-CoV fusion inhibitors against SARS-CoV-2 and its variants with preclinical evaluation

Signal transduction and targeted therapy, 2021-07, Vol.6 (1), p.288-288, Article 288

2021

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A bivalent protein targeting glycans and HR1 domain in spike protein potently inhibited infection of SARS-CoV-2 and other human coronaviruses

Cell & bioscience, 2021-07, Vol.11 (1), p.1-128, Article 128

2021

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Structure-based evidence for the enhanced transmissibility of the dominant SARS-CoV-2 B.1.1.7 variant (Alpha)

Cell discovery, 2021-11, Vol.7 (1), p.109-109, Article 109

2021

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The Analogs of Furanyl Methylidene Rhodanine Exhibit Broad-Spectrum Inhibitory and Inactivating Activities against Enveloped Viruses, including SARS-CoV-2 and Its Variants

Viruses, 2022-02, Vol.14 (3), p.489

2022

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Potent MERS-CoV Fusion Inhibitory Peptides Identified from HR2 Domain in Spike Protein of Bat Coronavirus HKU4

Viruses, 2019-01, Vol.11 (1), p.56

2019

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A highly potent and stable pan-coronavirus fusion inhibitor as a candidate prophylactic and therapeutic for COVID-19 and other coronavirus diseases

Acta pharmaceutica Sinica. B, 2022-04, Vol.12 (4), p.1652-1661

2022

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A Palmitic Acid-Conjugated, Peptide-Based pan-CoV Fusion Inhibitor Potently Inhibits Infection of SARS-CoV-2 Omicron and Other Variants of Concern

Viruses, 2022-03, Vol.14 (3), p.549

2022

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Clinical development of antivirals against SARS-CoV-2 and its variants

Current research in microbial sciences, 2024-01, Vol.6, p.100208-100208, Article 100208

2024

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Inefficiency of Sera from Mice Treated with Pseudotyped SARS-CoV to Neutralize 2019-nCoV Infection

Virologica Sinica, 2020-06, Vol.35 (3), p.340-343

2020

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Antigenic mapping reveals sites of vulnerability on α-HCoV spike protein

Communications biology, 2022-11, Vol.5 (1), p.1179-1179, Article 1179

2022

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Structure-based design of pan-coronavirus inhibitors targeting host cathepsin L and calpain-1

Signal transduction and targeted therapy, 2024-03, Vol.9 (1), p.54-54, Article 54

2024

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Coronavirus Entry Inhibitors

Advances in experimental medicine and biology, 2022, Vol.1366, p.101-121

2022

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V367F Mutation in SARS-CoV-2 Spike RBD Emerging during the Early Transmission Phase Enhances Viral Infectivity through Increased Human ACE2 Receptor Binding Affinity

Journal of virology, 2021-07, Vol.95 (16), p.e0061721

2021

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Supercoiling Structure-Based Design of a Trimeric Coiled-Coil Peptide with High Potency against HIV-1 and Human β-Coronavirus Infection

Journal of medicinal chemistry, 2022-02, Vol.65 (4), p.2809-2819

2022

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Lipopeptide-based pan-CoV fusion inhibitors potently inhibit HIV-1 infection

Microbes and infection, 2021-09, Vol.23 (8), p.104840-104840, Article 104840

2021

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Sodium Copper Chlorophyllin Is Highly Effective against Enterovirus (EV) A71 Infection by Blocking Its Entry into the Host Cell

ACS infectious diseases, 2020-05, Vol.6 (5), p.882-890

2020

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A core epitope targeting antibody of SARS-CoV-2

Protein & cell, 2023-01, Vol.14 (1), p.74-78

2023

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Fusion mechanism of 2019-nCoV and fusion inhibitors targeting HR1 domain in spike protein

The role of furin cleavage site in SARS-CoV-2 spike protein-mediated membrane fusion in the presence or absence of trypsin

Inhibition of SARS-CoV-2 (previously 2019-nCoV) infection by a highly potent pan-coronavirus fusion inhibitor targeting its spike protein that harbors a high capacity to mediate membrane fusion

Pan‐coronavirus fusion inhibitors to combat COVID‐19 and other emerging coronavirus infectious diseases

Development of oncolytic virotherapy: from genetic modification to combination therapy

Peptide-based pan-CoV fusion inhibitors maintain high potency against SARS-CoV-2 Omicron variant

25-Hydroxycholesterol-Conjugated EK1 Peptide with Potent and Broad-Spectrum Inhibitory Activity against SARS-CoV-2, Its Variants of Concern, and Other Human Coronaviruses

Structural and functional basis for pan-CoV fusion inhibitors against SARS-CoV-2 and its variants with preclinical evaluation

A bivalent protein targeting glycans and HR1 domain in spike protein potently inhibited infection of SARS-CoV-2 and other human coronaviruses

Structure-based evidence for the enhanced transmissibility of the dominant SARS-CoV-2 B.1.1.7 variant (Alpha)

The Analogs of Furanyl Methylidene Rhodanine Exhibit Broad-Spectrum Inhibitory and Inactivating Activities against Enveloped Viruses, including SARS-CoV-2 and Its Variants

Potent MERS-CoV Fusion Inhibitory Peptides Identified from HR2 Domain in Spike Protein of Bat Coronavirus HKU4

A highly potent and stable pan-coronavirus fusion inhibitor as a candidate prophylactic and therapeutic for COVID-19 and other coronavirus diseases

A Palmitic Acid-Conjugated, Peptide-Based pan-CoV Fusion Inhibitor Potently Inhibits Infection of SARS-CoV-2 Omicron and Other Variants of Concern

Clinical development of antivirals against SARS-CoV-2 and its variants

Inefficiency of Sera from Mice Treated with Pseudotyped SARS-CoV to Neutralize 2019-nCoV Infection

Antigenic mapping reveals sites of vulnerability on α-HCoV spike protein

Structure-based design of pan-coronavirus inhibitors targeting host cathepsin L and calpain-1

Coronavirus Entry Inhibitors

V367F Mutation in SARS-CoV-2 Spike RBD Emerging during the Early Transmission Phase Enhances Viral Infectivity through Increased Human ACE2 Receptor Binding Affinity

Supercoiling Structure-Based Design of a Trimeric Coiled-Coil Peptide with High Potency against HIV-1 and Human β-Coronavirus Infection

Lipopeptide-based pan-CoV fusion inhibitors potently inhibit HIV-1 infection

Sodium Copper Chlorophyllin Is Highly Effective against Enterovirus (EV) A71 Infection by Blocking Its Entry into the Host Cell

A core epitope targeting antibody of SARS-CoV-2

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