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Neonatal cytochrome P450 CYP3A7: A comprehensive review of its role in development, disease, and xenobiotic metabolism

Archives of biochemistry and biophysics, 2019-09, Vol.673, p.108078-108078, Article 108078

2019

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Role of Protein–Protein Interactions in Cytochrome P450-Mediated Drug Metabolism and Toxicity

Chemical research in toxicology, 2014-09, Vol.27 (9), p.1474-1486

2014

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Characterization of fluorescent probe substrates to develop an efficient high-throughput assay for neonatal hepatic CYP3A7 inhibition screening

Scientific reports, 2021-09, Vol.11 (1), p.19443-19443, Article 19443

2021

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Advances in the Understanding of Protein-Protein Interactions in Drug Metabolizing Enzymes through the Use of Biophysical Techniques

Frontiers in pharmacology, 2017-08, Vol.8, p.521-521

Lampe, Jed N

2017

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Common drugs inhibit human organic cation transporter 1 (OCT1)-mediated neurotransmitter uptake

Drug metabolism and disposition, 2014-06, Vol.42 (6), p.990-995

2014

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The role of hepatocyte nuclear factor 4-alpha in perfluorooctanoic acid- and perfluorooctanesulfonic acid-induced hepatocellular dysfunction

Toxicology and applied pharmacology, 2016-08, Vol.304, p.18-29

2016

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Aqueous synthesis of a small-molecule lanthanide chelator amenable to copper-free click chemistry

PloS one, 2019-03, Vol.14 (3), p.e0209726

2019

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Transcriptomics, metabolomics, and in-silico drug predictions for liver damage in young and aged burn victims

Communications biology, 2023-06, Vol.6 (1), p.597-597, Article 597

2023

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Drug metabolism of ciprofloxacin, ivacaftor, and raloxifene by Pseudomonas aeruginosa cytochrome P450 CYP107S1

The Journal of biological chemistry, 2024-08, Vol.300 (8), p.107594, Article 107594

2024

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Comparison of the CYP3A Selective Inhibitors CYP3cide, Clobetasol, and Azamulin for Their Potential to Distinguish CYP3A7 Activity in the Presence of CYP3A4/5

Drug metabolism and disposition, 2024-11, Vol.52 (11), p.1224-1233

2024

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HCV Antiviral Drugs Have the Potential to Adversely Perturb the Fetal-Maternal Communication Axis through Inhibition of CYP3A7 DHEA-S Oxidation

Drug metabolism and disposition, 2024-06, Vol.52 (6), p.516-525

2024

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Ligand-dependent modulation of hOCT1 transport reveals discrete ligand binding sites within the substrate translocation channel

Biochemical pharmacology, 2018-10, Vol.156, p.371-384

2018

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Correction: Human cytochrome P450 3A7 binding four copies of its native substrate dehydroepiandrosterone 3-sulfate

The Journal of biological chemistry, 2023-10, Vol.299 (10), p.105283-105283, Article 105283

2023

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Human cytochrome P450 3A7 binding four copies of its native substrate dehydroepiandrosterone 3-sulfate

The Journal of biological chemistry, 2023-08, Vol.299 (8), p.104993, Article 104993

2023

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Consideration of Nevirapine Analogs To Reduce Metabolically Linked Hepatotoxicity: A Cautionary Tale of the Deuteration Approach

Chemical research in toxicology, 2023-10, Vol.36 (10), p.1631-1642

2023

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Digging Deeper into CYP3A Testosterone Metabolism: Kinetic, Regioselectivity, and Stereoselectivity Differences between CYP3A4/5 and CYP3A7

Drug metabolism and disposition, 2017-12, Vol.45 (12), p.1266-1275

2017

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Inhibition of CYP3A7 DHEA‑S Oxidation by Lopinavir and Ritonavir: An Alternative Mechanism for Adrenal Impairment in HIV Antiretroviral-Treated Neonates

Chemical research in toxicology, 2021-04, Vol.34 (4), p.1150-1160

2021

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Identification of Aloe-derived natural products as prospective lead scaffolds for SARS-CoV-2 main protease (Mpro) inhibitors

Bioorganic & medicinal chemistry letters, 2022-06, Vol.66, p.128732-128732, Article 128732

2022

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Identification of Aloe‐derived natural products as lead scaffolds for SARS‐CoV‐2 main protease (Mpro) inhibitors

The FASEB journal, 2022-05, Vol.36 (S1), p.n/a

2022

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Utilization of CYP3A‐Specific Inhibitors to Study Cytochrome P450 CYP3A7 Activity in Neonatal Human Liver Microsomes

The FASEB journal, 2022-05, Vol.36 (S1), p.n/a

2022

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Pseudomonas aeruginosa cytochrome P450 CYP168A1 is a fatty acid hydroxylase that metabolizes arachidonic acid to the vasodilator 19-HETE

The Journal of biological chemistry, 2022-03, Vol.298 (3), p.101629-101629, Article 101629

2022

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Per- and polyfluoroalkyl substances (PFAS) inhibit cytochrome P450 CYP3A7 through direct coordination to the heme iron and water displacement

Journal of inorganic biochemistry, 2023-03, Vol.240, p.112120-112120, Article 112120

2023

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Fadraciclib (CYC065), a novel CDK inhibitor, targets key pro-survival and oncogenic pathways in cancer

PloS one, 2020-07, Vol.15 (7), p.e0234103-e0234103

2020

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Physiologically based metformin pharmacokinetics model of mice and scale-up to humans for the estimation of concentrations in various tissues

PloS one, 2021-04, Vol.16 (4), p.e0249594

2021

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Analysis of Cytochrome P450 CYP119 Ligand-dependent Conformational Dynamics by Two-dimensional NMR and X-ray Crystallography

The Journal of biological chemistry, 2015-04, Vol.290 (16), p.10000-10017

2015

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Neonatal cytochrome P450 CYP3A7: A comprehensive review of its role in development, disease, and xenobiotic metabolism

Role of Protein–Protein Interactions in Cytochrome P450-Mediated Drug Metabolism and Toxicity

Characterization of fluorescent probe substrates to develop an efficient high-throughput assay for neonatal hepatic CYP3A7 inhibition screening

Advances in the Understanding of Protein-Protein Interactions in Drug Metabolizing Enzymes through the Use of Biophysical Techniques

Common drugs inhibit human organic cation transporter 1 (OCT1)-mediated neurotransmitter uptake

The role of hepatocyte nuclear factor 4-alpha in perfluorooctanoic acid- and perfluorooctanesulfonic acid-induced hepatocellular dysfunction

Aqueous synthesis of a small-molecule lanthanide chelator amenable to copper-free click chemistry

Transcriptomics, metabolomics, and in-silico drug predictions for liver damage in young and aged burn victims

Drug metabolism of ciprofloxacin, ivacaftor, and raloxifene by Pseudomonas aeruginosa cytochrome P450 CYP107S1

Comparison of the CYP3A Selective Inhibitors CYP3cide, Clobetasol, and Azamulin for Their Potential to Distinguish CYP3A7 Activity in the Presence of CYP3A4/5

HCV Antiviral Drugs Have the Potential to Adversely Perturb the Fetal-Maternal Communication Axis through Inhibition of CYP3A7 DHEA-S Oxidation

Ligand-dependent modulation of hOCT1 transport reveals discrete ligand binding sites within the substrate translocation channel

Correction: Human cytochrome P450 3A7 binding four copies of its native substrate dehydroepiandrosterone 3-sulfate

Human cytochrome P450 3A7 binding four copies of its native substrate dehydroepiandrosterone 3-sulfate

Consideration of Nevirapine Analogs To Reduce Metabolically Linked Hepatotoxicity: A Cautionary Tale of the Deuteration Approach

Digging Deeper into CYP3A Testosterone Metabolism: Kinetic, Regioselectivity, and Stereoselectivity Differences between CYP3A4/5 and CYP3A7

Inhibition of CYP3A7 DHEA‑S Oxidation by Lopinavir and Ritonavir: An Alternative Mechanism for Adrenal Impairment in HIV Antiretroviral-Treated Neonates

Identification of Aloe-derived natural products as prospective lead scaffolds for SARS-CoV-2 main protease (Mpro) inhibitors

Identification of Aloe‐derived natural products as lead scaffolds for SARS‐CoV‐2 main protease (Mpro) inhibitors

Utilization of CYP3A‐Specific Inhibitors to Study Cytochrome P450 CYP3A7 Activity in Neonatal Human Liver Microsomes

Pseudomonas aeruginosa cytochrome P450 CYP168A1 is a fatty acid hydroxylase that metabolizes arachidonic acid to the vasodilator 19-HETE

Per- and polyfluoroalkyl substances (PFAS) inhibit cytochrome P450 CYP3A7 through direct coordination to the heme iron and water displacement

Fadraciclib (CYC065), a novel CDK inhibitor, targets key pro-survival and oncogenic pathways in cancer

Physiologically based metformin pharmacokinetics model of mice and scale-up to humans for the estimation of concentrations in various tissues

Analysis of Cytochrome P450 CYP119 Ligand-dependent Conformational Dynamics by Two-dimensional NMR and X-ray Crystallography

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