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Structural basis of PROTAC cooperative recognition for selective protein degradation

Nature chemical biology, 2017-05, Vol.13 (5), p.514

2017

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Homo-PROTACs: bivalent small-molecule dimerizers of the VHL E3 ubiquitin ligase to induce self-degradation

Nature communications, 2017-10, Vol.8 (1), p.830-14, Article 830

2017

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Keap1 perceives stress via three sensors for the endogenous signaling molecules nitric oxide, zinc, and alkenals

Proceedings of the National Academy of Sciences - PNAS, 2010-11, Vol.107 (44), p.18838-18843

2010

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Phenformin, But Not Metformin, Delays Development of T Cell Acute Lymphoblastic Leukemia/Lymphoma via Cell-Autonomous AMPK Activation

Cell reports (Cambridge), 2019-04, Vol.27 (3), p.690-698.e4

2019

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Cellular and Molecular Anatomy of the Human Neuromuscular Junction

Cell reports (Cambridge), 2017-11, Vol.21 (9), p.2348-2356

2017

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Reproducible Automated Phosphopeptide Enrichment Using Magnetic TiO2 and Ti-IMAC

Analytical chemistry (Washington), 2014-10, Vol.86 (20), p.10296-10302

2014

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Protein kinase IKKβ-catalyzed phosphorylation of IRF5 at Ser462 induces its dimerization and nuclear translocation in myeloid cells

Proceedings of the National Academy of Sciences - PNAS, 2014-12, Vol.111 (49), p.17432-17437

2014

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Mechanism of Activation of AMPK by Cordycepin

Cell chemical biology, 2020-02, Vol.27 (2), p.214-222.e4

2020

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Phosphorylation of Arabidopsis UVR8 photoreceptor modulates protein interactions and responses to UV-B radiation

Nature communications, 2024-02, Vol.15 (1), p.1221-1221, Article 1221

2024

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Analysis of Zika virus capsid-Aedes aegypti mosquito interactome reveals pro-viral host factors critical for establishing infection

Nature communications, 2021-05, Vol.12 (1), p.2766-2766, Article 2766

2021

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Mechanisms of Paradoxical Activation of AMPK by the Kinase Inhibitors SU6656 and Sorafenib

Cell chemical biology, 2017-07, Vol.24 (7), p.813-824.e4

2017

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Combining comparative proteomics and molecular genetics uncovers regulators of synaptic and axonal stability and degeneration in vivo

PLoS genetics, 2012-08, Vol.8 (8), p.e1002936-e1002936

2012

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A Quantitative Spatial Proteomics Analysis of Proteome Turnover in Human Cells

Molecular & cellular proteomics, 2012-03, Vol.11 (3), p.M111.011429-M111.011429, Article M111.011429

2012

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Heat Shock Factor 1 Is a Substrate for p38 Mitogen-Activated Protein Kinases

Molecular and cellular biology, 2016-09, Vol.36 (18), p.2403-2417

2016

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Proteome-wide identification and quantification of S-glutathionylation targets in mouse liver

Biochemical journal, 2015-07, Vol.469 (1), p.25-32

2015

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Aldolase is a sensor for both low and high glucose, linking to AMPK and mTORC1

Cell research, 2021-04, Vol.31 (4), p.478-481

2021

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Dysregulation of ubiquitin homeostasis and β-catenin signaling promote spinal muscular atrophy

The Journal of clinical investigation, 2014-04, Vol.124 (4), p.1821-1834

2014

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Molecular analysis of axonal-intrinsic and glial-associated co-regulation of axon degeneration

Cell death & disease, 2017-11, Vol.8 (11), p.e3166-e3166

2017

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Caspase cleavage and nuclear retention of the energy sensor AMPK-α1 during apoptosis

Cell reports (Cambridge), 2022-05, Vol.39 (5), p.110761-110761, Article 110761

2022

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Integrative proteomics highlight presynaptic alterations and c-Jun misactivation as convergent pathomechanisms in ALS

Acta neuropathologica, 2023-09, Vol.146 (3), p.451-475

2023

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The Salmonella Kinase SteC Targets the MAP Kinase MEK to Regulate the Host Actin Cytoskeleton

Cell host & microbe, 2012-11, Vol.12 (5), p.657-668

2012

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Altered mitochondrial bioenergetics are responsible for the delay in Wallerian degeneration observed in neonatal mice

Neurobiology of disease, 2019-10, Vol.130, p.104496, Article 104496

2019

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Pre-natal manifestation of systemic developmental abnormalities in spinal muscular atrophy

Human molecular genetics, 2020-09, Vol.29 (16), p.2674-2683

2020

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A Quantitative Proteomics Analysis of Subcellular Proteome Localization and Changes Induced by DNA Damage

Molecular & cellular proteomics, 2010-03, Vol.9 (3), p.457-470

2010

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Urinary peptidomics in a rodent model of diabetic nephropathy highlights epidermal growth factor as a biomarker for renal deterioration in patients with type 2 diabetes

Kidney international, 2016-05, Vol.89 (5), p.1125-1135

2016

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Structural basis of PROTAC cooperative recognition for selective protein degradation

Homo-PROTACs: bivalent small-molecule dimerizers of the VHL E3 ubiquitin ligase to induce self-degradation

Keap1 perceives stress via three sensors for the endogenous signaling molecules nitric oxide, zinc, and alkenals

Phenformin, But Not Metformin, Delays Development of T Cell Acute Lymphoblastic Leukemia/Lymphoma via Cell-Autonomous AMPK Activation

Cellular and Molecular Anatomy of the Human Neuromuscular Junction

Reproducible Automated Phosphopeptide Enrichment Using Magnetic TiO2 and Ti-IMAC

Protein kinase IKKβ-catalyzed phosphorylation of IRF5 at Ser462 induces its dimerization and nuclear translocation in myeloid cells

Mechanism of Activation of AMPK by Cordycepin

Phosphorylation of Arabidopsis UVR8 photoreceptor modulates protein interactions and responses to UV-B radiation

Analysis of Zika virus capsid-Aedes aegypti mosquito interactome reveals pro-viral host factors critical for establishing infection

Mechanisms of Paradoxical Activation of AMPK by the Kinase Inhibitors SU6656 and Sorafenib

Combining comparative proteomics and molecular genetics uncovers regulators of synaptic and axonal stability and degeneration in vivo

A Quantitative Spatial Proteomics Analysis of Proteome Turnover in Human Cells

Heat Shock Factor 1 Is a Substrate for p38 Mitogen-Activated Protein Kinases

Proteome-wide identification and quantification of S-glutathionylation targets in mouse liver

Aldolase is a sensor for both low and high glucose, linking to AMPK and mTORC1

Dysregulation of ubiquitin homeostasis and β-catenin signaling promote spinal muscular atrophy

Molecular analysis of axonal-intrinsic and glial-associated co-regulation of axon degeneration

Caspase cleavage and nuclear retention of the energy sensor AMPK-α1 during apoptosis

Integrative proteomics highlight presynaptic alterations and c-Jun misactivation as convergent pathomechanisms in ALS

The Salmonella Kinase SteC Targets the MAP Kinase MEK to Regulate the Host Actin Cytoskeleton

Altered mitochondrial bioenergetics are responsible for the delay in Wallerian degeneration observed in neonatal mice

Pre-natal manifestation of systemic developmental abnormalities in spinal muscular atrophy

A Quantitative Proteomics Analysis of Subcellular Proteome Localization and Changes Induced by DNA Damage

Urinary peptidomics in a rodent model of diabetic nephropathy highlights epidermal growth factor as a biomarker for renal deterioration in patients with type 2 diabetes

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