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Complement therapeutics in inflammatory diseases: promising drug candidates for C3-targeted intervention

Molecular oral microbiology, 2016-02, Vol.31 (1), p.3-17

2016

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Complement activation triggered by chondroitin sulfate released by thrombin receptor‐activated platelets

Journal of thrombosis and haemostasis, 2008-08, Vol.6 (8), p.1413-1421

2008

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Complement C3a and C5a modulate osteoclast formation and inflammatory response of osteoblasts in synergism with IL-1β

Journal of cellular biochemistry, 2011-09, Vol.112 (9), p.2594-2605

2011

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Complement Interactions with Blood Cells, Endothelial Cells and Microvesicles in Thrombotic and Inflammatory Conditions

Advances in experimental medicine and biology, 2015, Vol.865, p.19

2015

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Differential capacity for complement receptor‐mediated immune evasion by Porphyromonas gingivalis depending on the type of innate leukocyte

Molecular oral microbiology, 2017-04, Vol.32 (2), p.154-165

2017

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An ex vivo loop system models the toxicity and efficacy of PEGylated and unmodified adenovirus serotype 5 in whole human blood

Gene therapy, 2010-06, Vol.17 (6), p.752-762

2010

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Key role of tissue factor in complement-mediated coagulation activation by Escherichia coli and LPS

Molecular immunology, 2013-12, Vol.56 (3), p.250-250

2013

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Combined inhibition of C3 and CD14 attenuates the inflammatory reaction significantly more as compared to single inhibition

Molecular immunology, 2013-12, Vol.56 (3), p.304-305

2013

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Electrostatic contributions drive the interaction between Staphylococcus aureus protein Efb‐C and its complement target C3d

Protein science, 2008-11, Vol.17 (11), p.1894-1906

2008

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Key role of CD14 in the E. coli- and LPS-induced mRNA down regulation of the C5a receptors CD88 and C5L2

Molecular immunology, 2010-08, Vol.47 (13), p.2241-2241

2010

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Cholesterol crystals activate the complement system and are phagocytosed in a complement-dependent manner

Molecular immunology, 2013-12, Vol.56 (3), p.246-246

2013

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C5L2-mediated signals control contraction of human Th1 responses

Molecular immunology, 2013-12, Vol.56 (3), p.258-259

2013

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Differential effect of inhibiting MD-2 and CD14 on LPS- versus whole E. coli bacteria-induced cytokine responses in human blood

Molecular immunology, 2010-08, Vol.47 (13), p.2231-2231

2010

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C1 inhibitor efficiently inhibits Escherichia coli and LPS-induced tissue factor expression on monocytes and mRNA upregulation in human whole blood

Molecular immunology, 2011-08, Vol.48 (14), p.1669-1669

2011

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Pathogen-instigated subversive crosstalk between complement and Toll-like receptors

Molecular immunology, 2010-08, Vol.47 (13), p.2241-2241

2010

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Improvement of the anti-C3 activity of compstatin using rational and combinatorial approaches

Biochemical Society transactions, 2004-02, Vol.32 (Pt 1), p.28

2004

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CD59 Efficiently Protects Human NT2-N Neurons Against Complement-mediated Damage

Scandinavian journal of immunology, 2007-08, Vol.66 (2-3), p.345-351

2007

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From atoms to systems: a cross-disciplinary approach to complement-mediated functions

Molecular Immunology, 2004-06, Vol.41 (2), p.153-164

2004

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Complement is essential for phenotypic shift of leukocytes to a pro-inflammatory and pro-thrombotic state in a whole blood model of sepsis: Evidence from genetically complement-deficient patients

Molecular immunology, 2007-09, Vol.44 (16), p.3919-3919

2007

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Complement Component C5a Is Integral to the Febrile Response of Mice to Lipopolysaccharide

Neuroimmunomodulation, 2005-01, Vol.12 (2), p.67-80

2005

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Innate immunity in the Aegean: ancient pathways for today's survival

Developmental and comparative immunology, 2002-04, Vol.26 (3), p.217-225

2002

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Drusen complement components C3a and C5a promote choroidal neovascularization

American journal of ophthalmology, 2006-07, Vol.142 (1), p.201-201

2006

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Stathmin, a microtubule depolymerizing protein, Hsp25, Hsp27, and the antioxidant peroxiredoxin 6 are differentially expressed in a mouse model of familial amyotrophic lateral sclerosis

Revue neurologique, 2005-12, Vol.161 (12), p.1234-1234

2005

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Prolongation of ex vivo–perfused pig xenograft survival by the complement inhibitor compstatin

Transplantation proceedings, 1999-02, Vol.31 (1-2), p.934-935

1999

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Modulation of fluid-phase complement activation inhibits hyperacute rejection in a porcine-to-human xenograft model

Transplantation proceedings, 2000-08, Vol.32 (5), p.899-900

2000

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Complement therapeutics in inflammatory diseases: promising drug candidates for C3-targeted intervention

Complement activation triggered by chondroitin sulfate released by thrombin receptor‐activated platelets

Complement C3a and C5a modulate osteoclast formation and inflammatory response of osteoblasts in synergism with IL-1β

Complement Interactions with Blood Cells, Endothelial Cells and Microvesicles in Thrombotic and Inflammatory Conditions

Differential capacity for complement receptor‐mediated immune evasion by Porphyromonas gingivalis depending on the type of innate leukocyte

An ex vivo loop system models the toxicity and efficacy of PEGylated and unmodified adenovirus serotype 5 in whole human blood

Key role of tissue factor in complement-mediated coagulation activation by Escherichia coli and LPS

Combined inhibition of C3 and CD14 attenuates the inflammatory reaction significantly more as compared to single inhibition

Electrostatic contributions drive the interaction between Staphylococcus aureus protein Efb‐C and its complement target C3d

Key role of CD14 in the E. coli- and LPS-induced mRNA down regulation of the C5a receptors CD88 and C5L2

Cholesterol crystals activate the complement system and are phagocytosed in a complement-dependent manner

C5L2-mediated signals control contraction of human Th1 responses

Differential effect of inhibiting MD-2 and CD14 on LPS- versus whole E. coli bacteria-induced cytokine responses in human blood

C1 inhibitor efficiently inhibits Escherichia coli and LPS-induced tissue factor expression on monocytes and mRNA upregulation in human whole blood

Pathogen-instigated subversive crosstalk between complement and Toll-like receptors

Improvement of the anti-C3 activity of compstatin using rational and combinatorial approaches

CD59 Efficiently Protects Human NT2-N Neurons Against Complement-mediated Damage

From atoms to systems: a cross-disciplinary approach to complement-mediated functions

Complement is essential for phenotypic shift of leukocytes to a pro-inflammatory and pro-thrombotic state in a whole blood model of sepsis: Evidence from genetically complement-deficient patients

Complement Component C5a Is Integral to the Febrile Response of Mice to Lipopolysaccharide

Innate immunity in the Aegean: ancient pathways for today's survival

Drusen complement components C3a and C5a promote choroidal neovascularization

Stathmin, a microtubule depolymerizing protein, Hsp25, Hsp27, and the antioxidant peroxiredoxin 6 are differentially expressed in a mouse model of familial amyotrophic lateral sclerosis

Prolongation of ex vivo–perfused pig xenograft survival by the complement inhibitor compstatin

Modulation of fluid-phase complement activation inhibits hyperacute rejection in a porcine-to-human xenograft model

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