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Complement therapeutics in inflammatory diseases: promising drug candidates for C3-targeted intervention

Molecular oral microbiology, 2016-02, Vol.31 (1), p.3-17

2016

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Differential capacity for complement receptor‐mediated immune evasion by Porphyromonas gingivalis depending on the type of innate leukocyte

Molecular oral microbiology, 2017-04, Vol.32 (2), p.154-165

2017

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Complement C5a‐Induced Changes in Neutrophil Morphology During Inflammation

Scandinavian journal of immunology, 2017-09, Vol.86 (3), p.143-155

2017

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Complement inhibition in a xenogeneic model of interactions between human whole blood and porcine endothelium

Hormone and metabolic research, 2015-01, Vol.47 (1), p.36-42

2015

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Structure and biology of complement protein C3, a connecting link between innate and acquired immunity

Immunological reviews, 2001-04, Vol.180 (1), p.35-48

2001

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A Novel Role of Complement: Mice Deficient in the Fifth Component of Complement (C5) Exhibit Impaired Liver Regeneration

The Journal of immunology (1950), 2001-02, Vol.166 (4), p.2479-2486

2001

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The proinflammatory mediators C3a and C5a are essential for liver regeneration

The Journal of experimental medicine, 2003-09, Vol.198 (6), p.913-923

2003

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Complement activation triggered by chondroitin sulfate released by thrombin receptor‐activated platelets

Journal of thrombosis and haemostasis, 2008-08, Vol.6 (8), p.1413-1421

2008

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Diet-induced hepatocellular carcinoma in genetically predisposed mice

Human molecular genetics, 2009-08, Vol.18 (16), p.2975-2988

2009

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Prominent Neurodegeneration and Increased Plaque Formation in Complement-Inhibited Alzheimer's Mice

Proceedings of the National Academy of Sciences - PNAS, 2002-08, Vol.99 (16), p.10837-10842

2002

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An ex vivo loop system models the toxicity and efficacy of PEGylated and unmodified adenovirus serotype 5 in whole human blood

Gene therapy, 2010-06, Vol.17 (6), p.752-762

2010

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Differential effect of inhibiting MD-2 and CD14 on LPS- versus whole E. coli bacteria-induced cytokine responses in human blood

Advances in experimental medicine and biology, 2012-01, Vol.946, p.237

2012

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The complement system in teleosts

Fish & shellfish immunology, 2002-05, Vol.12 (5), p.399-420

2002

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Protective Effects of IL-6 Blockade in Sepsis Are Linked to Reduced C5a Receptor Expression

The Journal of immunology (1950), 2003-01, Vol.170 (1), p.503-507

2003

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Novel biological networks modulated by complement

Clinical immunology (Orlando, Fla.), 2005-06, Vol.115 (3), p.225-235

2005

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Complement: more than a ‘guard’ against invading pathogens?

Trends in immunology, 2002-10, Vol.23 (10), p.485-491

2002

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The artificial surface-induced whole blood inflammatory reaction revealed by increases in a series of chemokines and growth factors is largely complement dependent

Journal of biomedical materials research. Part A, 2008-10, Vol.87A (1), p.129-135

2008

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C1-inhibitor efficiently inhibits Escherichiacoli-induced tissue factor mRNA up-regulation, monocyte tissue factor expression and coagulation activation in human whole blood

Clinical and experimental immunology, 2013-08, Vol.173 (2), p.217

2013

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Iron oxide nanoparticles induce cytokine secretion in a complement-dependent manner in a human whole blood model

International journal of nanomedicine, 2017-01, Vol.12, p.3927-3940

2017

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C1‐inhibitor efficiently inhibits Escherichia coli‐induced tissue factor mRNA up‐regulation, monocyte tissue factor expression and coagulation activation in human whole blood

Clinical and experimental immunology, 2013-08, Vol.173 (2), p.217-229

2013

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Antibodies against the extracellular enveloped virus B5R protein are mainly responsible for the EEV neutralizing capacity of vaccinia immune globulin

Virology (New York, N.Y.), 2004-08, Vol.325 (2), p.425-431

2004

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Inhibition of human complement by a C3-binding peptide isolated from a phage-displayed random peptide library

The Journal of immunology (1950), 1996-07, Vol.157 (2), p.884-891

1996

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Binding Kinetics, Structure-Activity Relationship, and Biotransformation of the Complement Inhibitor Compstatin

The Journal of immunology (1950), 2000-09, Vol.165 (5), p.2491-2499

2000

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Complement C3 and C5 play critical roles in traumatic brain cryoinjury: blocking effects on neutrophil extravasation by C5a receptor antagonist

Journal of neuroimmunology, 2004-10, Vol.155 (1), p.55-63

2004

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Expression of Complement 3 and Complement 5 in Newt Limb and Lens Regeneration

The Journal of immunology (1950), 2003-03, Vol.170 (5), p.2331-2339

2003

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Molecular Sequence Data
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Complement therapeutics in inflammatory diseases: promising drug candidates for C3-targeted intervention

Differential capacity for complement receptor‐mediated immune evasion by Porphyromonas gingivalis depending on the type of innate leukocyte

Complement C5a‐Induced Changes in Neutrophil Morphology During Inflammation

Complement inhibition in a xenogeneic model of interactions between human whole blood and porcine endothelium

Structure and biology of complement protein C3, a connecting link between innate and acquired immunity

A Novel Role of Complement: Mice Deficient in the Fifth Component of Complement (C5) Exhibit Impaired Liver Regeneration

The proinflammatory mediators C3a and C5a are essential for liver regeneration

Complement activation triggered by chondroitin sulfate released by thrombin receptor‐activated platelets

Diet-induced hepatocellular carcinoma in genetically predisposed mice

Prominent Neurodegeneration and Increased Plaque Formation in Complement-Inhibited Alzheimer's Mice

An ex vivo loop system models the toxicity and efficacy of PEGylated and unmodified adenovirus serotype 5 in whole human blood

Differential effect of inhibiting MD-2 and CD14 on LPS- versus whole E. coli bacteria-induced cytokine responses in human blood

The complement system in teleosts

Protective Effects of IL-6 Blockade in Sepsis Are Linked to Reduced C5a Receptor Expression

Novel biological networks modulated by complement

Complement: more than a ‘guard’ against invading pathogens?

The artificial surface-induced whole blood inflammatory reaction revealed by increases in a series of chemokines and growth factors is largely complement dependent

C1-inhibitor efficiently inhibits Escherichiacoli-induced tissue factor mRNA up-regulation, monocyte tissue factor expression and coagulation activation in human whole blood

Iron oxide nanoparticles induce cytokine secretion in a complement-dependent manner in a human whole blood model

C1‐inhibitor efficiently inhibits Escherichia coli‐induced tissue factor mRNA up‐regulation, monocyte tissue factor expression and coagulation activation in human whole blood

Antibodies against the extracellular enveloped virus B5R protein are mainly responsible for the EEV neutralizing capacity of vaccinia immune globulin

Inhibition of human complement by a C3-binding peptide isolated from a phage-displayed random peptide library

Binding Kinetics, Structure-Activity Relationship, and Biotransformation of the Complement Inhibitor Compstatin

Complement C3 and C5 play critical roles in traumatic brain cryoinjury: blocking effects on neutrophil extravasation by C5a receptor antagonist

Expression of Complement 3 and Complement 5 in Newt Limb and Lens Regeneration

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