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Differences in the brain transcriptome of glial genes due to aging and active DNA Aβ42 and passive MOAB anti‐Aβ immunotherapy in the 3xTg‐AD mouse strain

Alzheimer's & dementia, 2021-12, Vol.17 (S3), p.e055191-n/a

2021

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Changes in the brain transcriptome after DNA Aβ42 trimer immunization in a 3xTg-AD mouse model

Neurobiology of disease, 2021-01, Vol.148, p.105221-105221, Article 105221

2021

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Active full-length DNA Aβ42 immunization in 3xTg-AD mice reduces not only amyloid deposition but also tau pathology

Alzheimer's research & therapy, 2018-11, Vol.10 (1), p.115-115, Article 115

2018

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Evaluation of a DNA Aβ42 vaccine in adult rhesus monkeys (Macaca mulatta): antibody kinetics and immune profile after intradermal immunization with full-length DNA Aβ42 trimer

Alzheimer's research & therapy, 2017-04, Vol.9 (1), p.30-30, Article 30

2017

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Glial cell transcriptome analyses in 3xTg-AD mice: Effects of aging, disease progression, and anti-Aβ immunotherapy

Aging brain, 2023, Vol.3, p.100066-100066, Article 100066

2023

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A Single Amino Acid Substitution Prevents Recognition of a Dominant Human Aquaporin-4 Determinant in the Context of HLA-DRB103:01 by a Murine TCR

PloS one, 2016-04, Vol.11 (4), p.e0152720-e0152720

2016

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Active DNA Aβ42 vaccination as immunotherapy for Alzheimer disease

Translational neuroscience, 2012-12, Vol.3 (4), p.307-313

2012

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Lymph node-derived donor encephalitogenic CD4+ T cells in C57BL/6 mice adoptive transfer experimental autoimmune encephalomyelitis highly express GM-CSF and T-bet

Journal of neuroinflammation, 2011-06, Vol.8 (1), p.73-73, Article 73

2011

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Genomics of Alzheimer Disease: A Review

JAMA neurology, 2016-07, Vol.73 (7), p.867

2016

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Active Immunotherapy to Prevent Alzheimer Disease-A DNA Amyloid β 1-42 Trimer Vaccine

JAMA neurology, 2020-03, Vol.77 (3), p.289

2020

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mouse major histocompatibility complex: some assembly required

Immunological reviews, 1999-02, Vol.167 (1), p.211-221

1999

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Intradermal DNA Aβ42 immunization via needle-less Jet injection as potential immunotherapy for Alzheimer’s disease

The Journal of immunology (1950), 2019-05, Vol.202 (1_Supplement), p.70-70.3

2019

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DNA Aβ42 immunotherapy induces epigenetic changes of the gene expression profile in brain in the 3XTG‐AD mouse model

Alzheimer's & dementia, 2020-12, Vol.16, p.n/a

2020

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DNA Aβ42 immunotherapy induces epigenetic changes of the gene expression profile in brain in the 3XTG‐AD mouse model: Nonhuman/Target identification and validation studies: Inflammation and innate immunity

Alzheimer's & dementia, 2020-12, Vol.16 (S9)

2020

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Advances in the development of vaccines for Alzheimer's disease

Discovery medicine, 2013-05, Vol.15 (84), p.319-326

2013

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HIGH LEVELS OF Aβ BOUND ANTIBODY IN PLASMA OF DNA Aβ42 TRIMER-IMMUNIZED 3XTG-AD MICE

Alzheimer's & dementia, 2019-07, Vol.15 (7), p.P1595-P1596

2019

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P4‐688: HIGH LEVELS OF Aβ BOUND ANTIBODY IN PLASMA OF DNA Aβ42 TRIMER‐IMMUNIZED 3XTG‐AD MICE

Alzheimer's & dementia, 2019-07, Vol.15 (7S_Part_31), p.P1595-P1596

2019

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DNA Aβ42 immunization via needle-less Jet injection in mice and rabbits as potential immunotherapy for Alzheimer's disease

Journal of the neurological sciences, 2023-03, Vol.446, p.120564-120564, Article 120564

2023

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Co-stimulation with TNF receptor superfamily 4/25 antibodies enhances in-vivo expansion of CD4 + CD25 + Foxp3 + T cells (Tregs) in a mouse study for active DNA Aβ42 immunotherapy

Journal of neuroimmunology, 2015-01, Vol.278, p.90-99

2015

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Intradermal active full-length DNA Aβ42 immunization via electroporation leads to high anti-Aβ antibody levels in wild-type mice with variability in T cell responses depending on pulse parameters applied

The Journal of immunology (1950), 2017-05, Vol.198 (1_Supplement), p.147-147.20

2017

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A noninflammatory immune response in aged DNA Aβ42-immunized mice supports its safety for possible use as immunotherapy in AD patients

Neurobiology of aging, 2015-03, Vol.36 (3), p.1274-1281

2015

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P4‐249: NEURODEGENERATION PROGRESSES IN CONCERT WITH INTRANEURONAL Aβ AND TAU PATHOLOGY IN THE 3XTG‐AD MOUSE MODEL

Alzheimer's & dementia, 2018-07, Vol.14 (7S_Part_29), p.P1541-P1541

2018

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A STRONG ANTI-Aβ42 IGA HUMORAL IMMUNE RESPONSE AFTER DNA Aβ42 TRIMER VACCINATION IN THE 3XTG-AD MOUSE MODEL

Alzheimer's & dementia, 2018-07, Vol.14 (7), p.P1540-P1541

2018

Volltextzugriff (PDF)

NEURODEGENERATION PROGRESSES IN CONCERT WITH INTRANEURONAL Aβ AND TAU PATHOLOGY IN THE 3XTG-AD MOUSE MODEL

Alzheimer's & dementia, 2018-07, Vol.14 (7), p.P1541-P1541

2018

Volltextzugriff (PDF)

P4‐248: A STRONG ANTI‐Aβ42 IGA HUMORAL IMMUNE RESPONSE AFTER DNA Aβ42 TRIMER VACCINATION IN THE 3XTG‐AD MOUSE MODEL

Alzheimer's & dementia, 2018-07, Vol.14 (7S_Part_29), p.P1540-P1541

2018

Volltextzugriff (PDF)

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Differences in the brain transcriptome of glial genes due to aging and active DNA Aβ42 and passive MOAB anti‐Aβ immunotherapy in the 3xTg‐AD mouse strain

Changes in the brain transcriptome after DNA Aβ42 trimer immunization in a 3xTg-AD mouse model

Active full-length DNA Aβ42 immunization in 3xTg-AD mice reduces not only amyloid deposition but also tau pathology

Evaluation of a DNA Aβ42 vaccine in adult rhesus monkeys (Macaca mulatta): antibody kinetics and immune profile after intradermal immunization with full-length DNA Aβ42 trimer

Glial cell transcriptome analyses in 3xTg-AD mice: Effects of aging, disease progression, and anti-Aβ immunotherapy

A Single Amino Acid Substitution Prevents Recognition of a Dominant Human Aquaporin-4 Determinant in the Context of HLA-DRB103:01 by a Murine TCR

Active DNA Aβ42 vaccination as immunotherapy for Alzheimer disease

Lymph node-derived donor encephalitogenic CD4+ T cells in C57BL/6 mice adoptive transfer experimental autoimmune encephalomyelitis highly express GM-CSF and T-bet

Genomics of Alzheimer Disease: A Review

Active Immunotherapy to Prevent Alzheimer Disease-A DNA Amyloid β 1-42 Trimer Vaccine

mouse major histocompatibility complex: some assembly required

Intradermal DNA Aβ42 immunization via needle-less Jet injection as potential immunotherapy for Alzheimer’s disease

DNA Aβ42 immunotherapy induces epigenetic changes of the gene expression profile in brain in the 3XTG‐AD mouse model

DNA Aβ42 immunotherapy induces epigenetic changes of the gene expression profile in brain in the 3XTG‐AD mouse model: Nonhuman/Target identification and validation studies: Inflammation and innate immunity

Advances in the development of vaccines for Alzheimer's disease

HIGH LEVELS OF Aβ BOUND ANTIBODY IN PLASMA OF DNA Aβ42 TRIMER-IMMUNIZED 3XTG-AD MICE

P4‐688: HIGH LEVELS OF Aβ BOUND ANTIBODY IN PLASMA OF DNA Aβ42 TRIMER‐IMMUNIZED 3XTG‐AD MICE

DNA Aβ42 immunization via needle-less Jet injection in mice and rabbits as potential immunotherapy for Alzheimer's disease

Co-stimulation with TNF receptor superfamily 4/25 antibodies enhances in-vivo expansion of CD4 + CD25 + Foxp3 + T cells (Tregs) in a mouse study for active DNA Aβ42 immunotherapy

Intradermal active full-length DNA Aβ42 immunization via electroporation leads to high anti-Aβ antibody levels in wild-type mice with variability in T cell responses depending on pulse parameters applied

A noninflammatory immune response in aged DNA Aβ42-immunized mice supports its safety for possible use as immunotherapy in AD patients

P4‐249: NEURODEGENERATION PROGRESSES IN CONCERT WITH INTRANEURONAL Aβ AND TAU PATHOLOGY IN THE 3XTG‐AD MOUSE MODEL

A STRONG ANTI-Aβ42 IGA HUMORAL IMMUNE RESPONSE AFTER DNA Aβ42 TRIMER VACCINATION IN THE 3XTG-AD MOUSE MODEL

NEURODEGENERATION PROGRESSES IN CONCERT WITH INTRANEURONAL Aβ AND TAU PATHOLOGY IN THE 3XTG-AD MOUSE MODEL

P4‐248: A STRONG ANTI‐Aβ42 IGA HUMORAL IMMUNE RESPONSE AFTER DNA Aβ42 TRIMER VACCINATION IN THE 3XTG‐AD MOUSE MODEL

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