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Nox enzymes, ROS, and chronic disease: An example of antagonistic pleiotropy

Free radical biology & medicine, 2007-08, Vol.43 (3), p.332-347

Lambeth, J. David

2007

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Nox enzymes and new thinking on reactive oxygen: a double-edged sword revisited

Annual review of pathology, 2014-01, Vol.9 (1), p.119-145

2014

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On the use of L-012, a luminol-based chemiluminescent probe, for detecting superoxide and identifying inhibitors of NADPH oxidase: a reevaluation

Free radical biology & medicine, 2013-12, Vol.65, p.1310-1314

2013

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Regulation of Nox and Duox enzymatic activity and expression

Free radical biology & medicine, 2007-08, Vol.43 (3), p.319-331

2007

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Symbiotic lactobacilli stimulate gut epithelial proliferation via Nox-mediated generation of reactive oxygen species

The EMBO journal, 2013-11, Vol.32 (23), p.3017-3028

2013

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Molecular evolution of the reactive oxygen-generating NADPH oxidase (Nox/Duox) family of enzymes

BMC evolutionary biology, 2007-07, Vol.7, p.109

2007

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Nox1-dependent Reactive Oxygen Generation Is Regulated by Rac1

The Journal of biological chemistry, 2006-06, Vol.281 (26), p.17718-17726

2006

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Small-molecule NOX inhibitors: ROS-generating NADPH oxidases as therapeutic targets

Antioxidants & redox signaling, 2009-10, Vol.11 (10), p.2535

2009

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Constitutive NADPH-Dependent Electron Transferase Activity of the Nox4 Dehydrogenase Domain

Biochemistry (Easton), 2010-03, Vol.49 (11), p.2433-2442

2010

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NOX enzymes as novel targets for drug development

Seminars in immunopathology, 2008-07, Vol.30 (3), p.339-363

2008

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Upregulation of Nox1 in vascular smooth muscle leads to impaired endothelium-dependent relaxation via eNOS uncoupling

American journal of physiology. Heart and circulatory physiology, 2010-09, Vol.299 (3), p.H673-H679

2010

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Microbicidal Activity of Vascular Peroxidase 1 in Human Plasma via Generation of Hypochlorous Acid

Infection and Immunity, 2012-07, Vol.80 (7), p.2528-2537

2012

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The superoxide-generating oxidase Nox1 is functionally required for Ras oncogene transformation

Cancer research (Chicago, Ill.), 2004-05, Vol.64 (10), p.3580-3585

2004

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NOX enzymes as novel targets for drug development

Seminars in immunopathology, 2008-07, Vol.30 (3), p.339-363

2008

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Distinct subcellular localizations of Nox1 and Nox4 in vascular smooth muscle cells

Arteriosclerosis, thrombosis, and vascular biology, 2004-04, Vol.24 (4), p.677

2004

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Molecular evolution of Phox-related regulatory subunits for NADPH oxidase enzymes

BMC evolutionary biology, 2007-09, Vol.7, p.178

2007

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Nox1 overexpression potentiates angiotensin II-induced hypertension and vascular smooth muscle hypertrophy in transgenic mice

Circulation (New York, N.Y.), 2005-10, Vol.112 (17), p.2668-2676

2005

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Amyloid-β and proinflammatory cytokines utilize a prion protein-dependent pathway to activate NADPH oxidase and induce cofilin-actin rods in hippocampal neurons

PloS one, 2014-04, Vol.9 (4), p.e95995

2014

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The NAD(P)H Oxidase Homolog Nox4 Modulates Insulin-Stimulated Generation of H2O2 and Plays an Integral Role in Insulin Signal Transduction

Molecular and Cellular Biology, 2004-03, Vol.24 (5), p.1844-1854

2004

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Role of Nox4 and Nox2 in hyperoxia-induced reactive oxygen species generation and migration of human lung endothelial cells

Antioxidants & redox signaling, 2009-04, Vol.11 (4), p.747

2009

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NOXO1, Regulation of Lipid Binding, Localization, and Activation of Nox1 by the Phox Homology (PX) Domain

The Journal of biological chemistry, 2004-02, Vol.279 (6), p.4737-4742

2004

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Mechanisms of vascular smooth muscle NADPH oxidase 1 (Nox1) contribution to injury-induced neointimal formation

Arteriosclerosis, thrombosis, and vascular biology, 2009-04, Vol.29 (4), p.480

2009

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Nox/Duox family of nicotinamide adenine dinucleotide (phosphate) oxidases

Current opinion in hematology, 2002-01, Vol.9 (1), p.11-17

Lambeth, J David

2002

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Contrasting Roles of NADPH Oxidase Isoforms in Pressure-Overload Versus Angiotensin II–Induced Cardiac Hypertrophy

Circulation research, 2003-10, Vol.93 (9), p.802-804

2003

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Quinazolin-derived myeloperoxidase inhibitor suppresses influenza A virus-induced reactive oxygen species, pro-inflammatory mediators and improves cell survival

PloS one, 2021-07, Vol.16 (7), p.e0254632-e0254632

2021

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Nox enzymes, ROS, and chronic disease: An example of antagonistic pleiotropy

Nox enzymes and new thinking on reactive oxygen: a double-edged sword revisited

On the use of L-012, a luminol-based chemiluminescent probe, for detecting superoxide and identifying inhibitors of NADPH oxidase: a reevaluation

Regulation of Nox and Duox enzymatic activity and expression

Symbiotic lactobacilli stimulate gut epithelial proliferation via Nox-mediated generation of reactive oxygen species

Molecular evolution of the reactive oxygen-generating NADPH oxidase (Nox/Duox) family of enzymes

Nox1-dependent Reactive Oxygen Generation Is Regulated by Rac1

Small-molecule NOX inhibitors: ROS-generating NADPH oxidases as therapeutic targets

Constitutive NADPH-Dependent Electron Transferase Activity of the Nox4 Dehydrogenase Domain

NOX enzymes as novel targets for drug development

Upregulation of Nox1 in vascular smooth muscle leads to impaired endothelium-dependent relaxation via eNOS uncoupling

Microbicidal Activity of Vascular Peroxidase 1 in Human Plasma via Generation of Hypochlorous Acid

The superoxide-generating oxidase Nox1 is functionally required for Ras oncogene transformation

NOX enzymes as novel targets for drug development

Distinct subcellular localizations of Nox1 and Nox4 in vascular smooth muscle cells

Molecular evolution of Phox-related regulatory subunits for NADPH oxidase enzymes

Nox1 overexpression potentiates angiotensin II-induced hypertension and vascular smooth muscle hypertrophy in transgenic mice

Amyloid-β and proinflammatory cytokines utilize a prion protein-dependent pathway to activate NADPH oxidase and induce cofilin-actin rods in hippocampal neurons

The NAD(P)H Oxidase Homolog Nox4 Modulates Insulin-Stimulated Generation of H2O2 and Plays an Integral Role in Insulin Signal Transduction

Role of Nox4 and Nox2 in hyperoxia-induced reactive oxygen species generation and migration of human lung endothelial cells

NOXO1, Regulation of Lipid Binding, Localization, and Activation of Nox1 by the Phox Homology (PX) Domain

Mechanisms of vascular smooth muscle NADPH oxidase 1 (Nox1) contribution to injury-induced neointimal formation

Nox/Duox family of nicotinamide adenine dinucleotide (phosphate) oxidases

Contrasting Roles of NADPH Oxidase Isoforms in Pressure-Overload Versus Angiotensin II–Induced Cardiac Hypertrophy

Quinazolin-derived myeloperoxidase inhibitor suppresses influenza A virus-induced reactive oxygen species, pro-inflammatory mediators and improves cell survival

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