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GABAA receptor-acting neurosteroids: A role in the development and regulation of the stress response

Frontiers in neuroendocrinology, 2015-01, Vol.36, p.28-48

2015

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Dysfunctional astrocytic and synaptic regulation of hypothalamic glutamatergic transmission in a mouse model of early-life adversity: relevance to neurosteroids and programming of the stress response

The Journal of neuroscience, 2013-12, Vol.33 (50), p.19534-19554

2013

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Realising the therapeutic potential of neuroactive steroid modulators of the GABAA receptor

Neurobiology of stress, 2020-05, Vol.12, p.100207-100207, Article 100207

2020

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Neurosteroids: endogenous regulators of the GABAA receptor

Nature reviews. Neuroscience, 2005-06, Vol.6 (7), p.565-575

2005

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Extrasynaptic Glycine Receptors of Rodent Dorsal Raphe Serotonergic Neurons: A Sensitive Target for Ethanol

Neuropsychopharmacology (New York, N.Y.), 2014-04, Vol.39 (5), p.1232-1244

2014

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Neurosteroid Modulation of Synaptic and Extrasynaptic GABAA Receptors of the Mouse Nucleus Accumbens

Biomolecules (Basel, Switzerland), 2024-04, Vol.14 (4), p.460

2024

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Developmentally regulated neurosteroid synthesis enhances GABAergic neurotransmission in mouse thalamocortical neurones

The Journal of physiology, 2015-01, Vol.593 (1), p.267-284

2015

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Neurosteroid modulation of GABAA receptors: molecular determinants and significance in health and disease

Neurochemistry international, 2008-03, Vol.52 (4-5), p.588-595

2008

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Cocaine effects on mouse incentive-learning and human addiction are linked to α2 subunit-containing GABAA receptors

Proceedings of the National Academy of Sciences - PNAS, 2010-02, Vol.107 (5), p.2289-2294

2010

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Early-life adversity increases morphine tolerance and persistent inflammatory hypersensitivity through upregulation of δ opioid receptors in mice

Pain (Amsterdam), 2023-10, Vol.164 (10), p.2253-2264

2023

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Relating neurosteroid modulation of inhibitory neurotransmission to behaviour

Journal of neuroendocrinology, 2022-02, Vol.34 (2), p.e13045-n/a

2022

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Developmental maturation of synaptic and extrasynaptic GABAA receptors in mouse thalamic ventrobasal neurones

The Journal of physiology, 2008-02, Vol.586 (4), p.965-987

2008

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Novel structural determinants of single channel conductance and ion selectivity in 5-hydroxytryptamine type 3 and nicotinic acetylcholine receptors

The Journal of physiology, 2010-02, Vol.588 (4), p.587-596

2010

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The Interaction of the General Anesthetic Etomidate with the γ -Aminobutyric Acid Type a Receptor is Influenced by a Single Amino Acid

Proceedings of the National Academy of Sciences - PNAS, 1997-09, Vol.94 (20), p.11031-11036

1997

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Realising the therapeutic potential of neuroactive steroid modulators of the GABA A receptor

Neurobiology of stress, 2020-05, Vol.12, p.100207

2020

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Phenotypical Screening on Neuronal Plasticity in Hippocampal-Prefrontal Cortex Connectivity Reveals an Antipsychotic with a Novel Profile

Cells (Basel, Switzerland), 2022-03, Vol.11 (7), p.1181

2022

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Early stress-induced impaired microglial pruning of excitatory synapses on immature CRH-expressing neurons provokes aberrant adult stress responses

Cell reports (Cambridge), 2022-03, Vol.38 (13), p.110600-110600, Article 110600

2022

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Neurosteroid modulation of synaptic and extrasynaptic GABAA receptors

Pharmacology & therapeutics (Oxford), 2007-10, Vol.116 (1), p.20-34

2007

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Extrasynaptic GABA(A) receptors couple presynaptic activity to postsynaptic inhibition in the somatosensory thalamus

The Journal of neuroscience, 2013-09, Vol.33 (37), p.14850-14868

2013

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Extrasynaptic GABAA Receptors Couple Presynaptic Activity to Postsynaptic Inhibition in the Somatosensory Thalamus

The Journal of neuroscience, 2013-09, Vol.33 (37), p.14850-14868

2013

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Molecular determinants of single-channel conductance and ion selectivity in the Cys-loop family: insights from the 5-HT3 receptor

Trends in pharmacological sciences (Regular ed.), 2005-11, Vol.26 (11), p.587-594

2005

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Bi-directional modulation of fast inhibitory synaptic transmission by leptin

Journal of neurochemistry, 2009-01, Vol.108 (1), p.190-201

2009

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Identification of intraneuronal amyloid beta oligomers in locus coeruleus neurons of Alzheimer’s patients and their potential impact on inhibitory neurotransmitter receptors and neuronal excitability

Neuropathology and applied neurobiology, 2021-06, Vol.47 (4), p.488-505

2021

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Structural Determinants of Ca2+ Permeability and Conduction in the Human 5-Hydroxytryptamine Type 3A Receptor

The Journal of biological chemistry, 2008-07, Vol.283 (28), p.19301-19313

2008

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GABAA receptor-acting neurosteroids: A role in the development and regulation of the stress response

Dysfunctional astrocytic and synaptic regulation of hypothalamic glutamatergic transmission in a mouse model of early-life adversity: relevance to neurosteroids and programming of the stress response

Realising the therapeutic potential of neuroactive steroid modulators of the GABAA receptor

Metformin reverses early cortical network dysfunction and behavior changes in Huntington's disease

Neurosteroids: endogenous regulators of the GABAA receptor

Extrasynaptic Glycine Receptors of Rodent Dorsal Raphe Serotonergic Neurons: A Sensitive Target for Ethanol

Neurosteroid Modulation of Synaptic and Extrasynaptic GABAA Receptors of the Mouse Nucleus Accumbens

Developmentally regulated neurosteroid synthesis enhances GABAergic neurotransmission in mouse thalamocortical neurones

Neurosteroid modulation of GABAA receptors: molecular determinants and significance in health and disease

Cocaine effects on mouse incentive-learning and human addiction are linked to α2 subunit-containing GABAA receptors

Early-life adversity increases morphine tolerance and persistent inflammatory hypersensitivity through upregulation of δ opioid receptors in mice

Relating neurosteroid modulation of inhibitory neurotransmission to behaviour

Developmental maturation of synaptic and extrasynaptic GABAA receptors in mouse thalamic ventrobasal neurones

Novel structural determinants of single channel conductance and ion selectivity in 5-hydroxytryptamine type 3 and nicotinic acetylcholine receptors

The Interaction of the General Anesthetic Etomidate with the γ -Aminobutyric Acid Type a Receptor is Influenced by a Single Amino Acid

Realising the therapeutic potential of neuroactive steroid modulators of the GABA A receptor

Phenotypical Screening on Neuronal Plasticity in Hippocampal-Prefrontal Cortex Connectivity Reveals an Antipsychotic with a Novel Profile

Early stress-induced impaired microglial pruning of excitatory synapses on immature CRH-expressing neurons provokes aberrant adult stress responses

Neurosteroid modulation of synaptic and extrasynaptic GABAA receptors

Extrasynaptic GABA(A) receptors couple presynaptic activity to postsynaptic inhibition in the somatosensory thalamus

Extrasynaptic GABAA Receptors Couple Presynaptic Activity to Postsynaptic Inhibition in the Somatosensory Thalamus

Molecular determinants of single-channel conductance and ion selectivity in the Cys-loop family: insights from the 5-HT3 receptor

Bi-directional modulation of fast inhibitory synaptic transmission by leptin

Identification of intraneuronal amyloid beta oligomers in locus coeruleus neurons of Alzheimer’s patients and their potential impact on inhibitory neurotransmitter receptors and neuronal excitability

Structural Determinants of Ca2+ Permeability and Conduction in the Human 5-Hydroxytryptamine Type 3A Receptor

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