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Metal ions shape α-synuclein

Scientific reports, 2020-10, Vol.10 (1), p.16293-16293, Article 16293

2020

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Regulation of intestinal permeability: The role of proteases

World journal of gastroenterology : WJG, 2017-03, Vol.23 (12), p.2106-2123

2017

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The Dipeptidyl Peptidase Family, Prolyl Oligopeptidase, and Prolyl Carboxypeptidase in the Immune System and Inflammatory Disease, Including Atherosclerosis

Frontiers in immunology, 2015-08, Vol.6, p.387-387

2015

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Raman optical activity of human α‐synuclein in intrinsically disordered, micelle‐bound α‐helical, molten globule and oligomeric β‐sheet state

Journal of Raman spectroscopy, 2017-07, Vol.48 (7), p.910-918

2017

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Efforts towards an On‐Target Version of the Groebke–Blackburn–Bienaymé (GBB) Reaction for Discovery of Druglike Urokinase (uPA) Inhibitors

Chemistry : a European journal, 2019-09, Vol.25 (53), p.12380-12393

2019

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Newly developed serine protease inhibitors decrease visceral hypersensitivity in a post‐inflammatory rat model for irritable bowel syndrome

British journal of pharmacology, 2018-09, Vol.175 (17), p.3516-3533

2018

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Inhibition of the procarboxypeptidase U (proCPU, TAFI, proCPB2) system due to hemolysis

Journal of thrombosis and haemostasis, 2019-06, Vol.17 (6), p.878-884

2019

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Small molecule 3PO inhibits glycolysis but does not bind to 6‐phosphofructo‐2‐kinase/fructose‐2,6‐bisphosphatase‐3 (PFKFB3)

FEBS letters, 2020-09, Vol.594 (18), p.3067-3075

2020

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Selective inhibition of carboxypeptidase U may reduce microvascular thrombosis in rat experimental stroke

Journal of thrombosis and haemostasis, 2020-12, Vol.18 (12), p.3325-3335

2020

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Prolyl Carboxypeptidase Mediates the C-Terminal Cleavage of (Pyr)-Apelin-13 in Human Umbilical Vein and Aortic Endothelial Cells

International journal of molecular sciences, 2021-07, Vol.22 (13), p.6698

2021

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The effect of prolyl oligopeptidase inhibitors on alpha-synuclein aggregation and autophagy cannot be predicted by their inhibitory efficacy

Biomedicine & pharmacotherapy, 2020-08, Vol.128, p.110253, Article 110253

2020

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Interaction of prolyl oligopeptidase with α-synuclein

CNS & neurological disorders drug targets, 2011-05, Vol.10 (3), p.349

Lambeir, Anne-Marie

2011

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Dysregulated activities of proline-specific enzymes in septic shock patients (sepsis-2)

PloS one, 2020-04, Vol.15 (4), p.e0231555-e0231555

2020

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Effects of Detergent on α-Synuclein Structure. A Native MS-Ion Mobility Study

International journal of molecular sciences, 2020-10, Vol.21 (21), p.7884

2020

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Visceral hypersensitivity in inflammatory bowel diseases and irritable bowel syndrome: The role of proteases

World journal of gastroenterology : WJG, 2016-12, Vol.22 (47), p.10275-10286

2016

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Dynamics and ligand-induced conformational changes in human prolyl oligopeptidase analyzed by hydrogen/deuterium exchange mass spectrometry

Scientific reports, 2017-05, Vol.7 (1), p.2456-13, Article 2456

2017

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Proteolytic Cleavage of Bioactive Peptides and Protease-Activated Receptors in Acute and Post-Colitis

International journal of molecular sciences, 2021-10, Vol.22 (19), p.10711

2021

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Extended Structure–Activity Relationship and Pharmacokinetic Investigation of (4-Quinolinoyl)glycyl-2-cyanopyrrolidine Inhibitors of Fibroblast Activation Protein (FAP)

Journal of medicinal chemistry, 2014-04, Vol.57 (7), p.3053-3074

2014

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Prolyl carboxypeptidase activity in the circulation and its correlation with body weight and adipose tissue in lean and obese subjects

PloS one, 2018-05, Vol.13 (5), p.e0197603-e0197603

2018

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Crystal structure of Porphyromonas gingivalis dipeptidyl peptidase 4 and structure-activity relationships based on inhibitor profiling

European journal of medicinal chemistry, 2017-10, Vol.139, p.482-491

2017

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The Effect of a Novel Serine Protease Inhibitor on Inflammation and Intestinal Permeability in a Murine Colitis Transfer Model

Frontiers in pharmacology, 2021-06, Vol.12, p.682065-682065

2021

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Structure–Activity Relationship Studies on Isoindoline Inhibitors of Dipeptidyl Peptidases 8 and 9 (DPP8, DPP9): Is DPP8-Selectivity an Attainable Goal?

Journal of medicinal chemistry, 2011-08, Vol.54 (16), p.5737-5746

2011

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Translational research on prolyl oligopeptidase inhibitors: the long road ahead

Expert opinion on therapeutic patents, 2011-07, Vol.21 (7), p.977-981

Lambeir, Anne-Marie

2011

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Carboxypeptidase M Expressed by Human Bone Marrow Cells Cleaves the C‐Terminal Lysine of Stromal Cell‐Derived Factor‐1α: Another Player in Hematopoietic Stem/Progenitor Cell Mobilization?

Stem cells (Dayton, Ohio), 2008-05, Vol.26 (5), p.1211-1220

2008

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The potential of carboxypeptidase M as a therapeutic target in cancer

Expert opinion on therapeutic targets, 2013-03, Vol.17 (3), p.265-279

2013

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Metal ions shape α-synuclein

Regulation of intestinal permeability: The role of proteases

The Dipeptidyl Peptidase Family, Prolyl Oligopeptidase, and Prolyl Carboxypeptidase in the Immune System and Inflammatory Disease, Including Atherosclerosis

Raman optical activity of human α‐synuclein in intrinsically disordered, micelle‐bound α‐helical, molten globule and oligomeric β‐sheet state

Efforts towards an On‐Target Version of the Groebke–Blackburn–Bienaymé (GBB) Reaction for Discovery of Druglike Urokinase (uPA) Inhibitors

Newly developed serine protease inhibitors decrease visceral hypersensitivity in a post‐inflammatory rat model for irritable bowel syndrome

Inhibition of the procarboxypeptidase U (proCPU, TAFI, proCPB2) system due to hemolysis

Small molecule 3PO inhibits glycolysis but does not bind to 6‐phosphofructo‐2‐kinase/fructose‐2,6‐bisphosphatase‐3 (PFKFB3)

Selective inhibition of carboxypeptidase U may reduce microvascular thrombosis in rat experimental stroke

Prolyl Carboxypeptidase Mediates the C-Terminal Cleavage of (Pyr)-Apelin-13 in Human Umbilical Vein and Aortic Endothelial Cells

The effect of prolyl oligopeptidase inhibitors on alpha-synuclein aggregation and autophagy cannot be predicted by their inhibitory efficacy

Interaction of prolyl oligopeptidase with α-synuclein

Dysregulated activities of proline-specific enzymes in septic shock patients (sepsis-2)

Effects of Detergent on α-Synuclein Structure. A Native MS-Ion Mobility Study

Visceral hypersensitivity in inflammatory bowel diseases and irritable bowel syndrome: The role of proteases

Dynamics and ligand-induced conformational changes in human prolyl oligopeptidase analyzed by hydrogen/deuterium exchange mass spectrometry

Proteolytic Cleavage of Bioactive Peptides and Protease-Activated Receptors in Acute and Post-Colitis

Extended Structure–Activity Relationship and Pharmacokinetic Investigation of (4-Quinolinoyl)glycyl-2-cyanopyrrolidine Inhibitors of Fibroblast Activation Protein (FAP)

Prolyl carboxypeptidase activity in the circulation and its correlation with body weight and adipose tissue in lean and obese subjects

Crystal structure of Porphyromonas gingivalis dipeptidyl peptidase 4 and structure-activity relationships based on inhibitor profiling

The Effect of a Novel Serine Protease Inhibitor on Inflammation and Intestinal Permeability in a Murine Colitis Transfer Model

Structure–Activity Relationship Studies on Isoindoline Inhibitors of Dipeptidyl Peptidases 8 and 9 (DPP8, DPP9): Is DPP8-Selectivity an Attainable Goal?

Translational research on prolyl oligopeptidase inhibitors: the long road ahead

Carboxypeptidase M Expressed by Human Bone Marrow Cells Cleaves the C‐Terminal Lysine of Stromal Cell‐Derived Factor‐1α: Another Player in Hematopoietic Stem/Progenitor Cell Mobilization?

The potential of carboxypeptidase M as a therapeutic target in cancer

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