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George Aghajanian (1932–2023)

Nature neuroscience, 2023-12, Vol.26 (12), p.2046-2047

Lambe, Evelyn K.

2023

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Chrna5 is Essential for a Rapid and Protected Response to Optogenetic Release of Endogenous Acetylcholine in Prefrontal Cortex

The Journal of neuroscience, 2020-09, Vol.40 (38), p.7255-7268

2020

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Xanomeline restores endogenous nicotinic acetylcholine receptor signaling in mouse prefrontal cortex

Neuropsychopharmacology (New York, N.Y.), 2023-03, Vol.48 (4), p.671-682

2023

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Median raphe serotonin neurons promote anxiety-like behavior via inputs to the dorsal hippocampus

Neuropharmacology, 2020-05, Vol.168, p.107985-107985, Article 107985

2020

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Cholecystokinin-Expressing Interneurons of the Medial Prefrontal Cortex Mediate Working Memory Retrieval

The Journal of neuroscience, 2020-03, Vol.40 (11), p.2314-2331

2020

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Chronic social isolation reduces 5-HT neuronal activity via upregulated SK3 calcium-activated potassium channels

eLife, 2016-11, Vol.5

2016

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Deficits in integrative NMDA receptors caused by Grin1 disruption can be rescued in adulthood

Neuropsychopharmacology (New York, N.Y.), 2023-11, Vol.48 (12), p.1742-1751

2023

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Hippocampal 5-HT Input Regulates Memory Formation and Schaffer Collateral Excitation

Neuron (Cambridge, Mass.), 2018-06, Vol.98 (5), p.992-1004.e4

2018

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Chrna5-Expressing Neurons in the Interpeduncular Nucleus Mediate Aversion Primed by Prior Stimulation or Nicotine Exposure

The Journal of neuroscience, 2018-08, Vol.38 (31), p.6900-6920

2018

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Schizophrenia susceptibility pathway neuregulin 1-ErbB4 suppresses Src upregulation of NMDA receptors

Nature medicine, 2011-04, Vol.17 (4), p.470-478

2011

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Postnatal day 2 to 11 constitutes a 5-HT-sensitive period impacting adult mPFC function

The Journal of neuroscience, 2014-09, Vol.34 (37), p.12379-12393

2014

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Dorsal raphe serotonin neurons inhibit operant responding for reward via inputs to the ventral tegmental area but not the nucleus accumbens: evidence from studies combining optogenetic stimulation and serotonin reuptake inhibition

Neuropsychopharmacology (New York, N.Y.), 2019-03, Vol.44 (4), p.793-804

2019

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Serotonin receptor expression in human prefrontal cortex: balancing excitation and inhibition across postnatal development

PloS one, 2011-07, Vol.6 (7), p.e22799-e22799

2011

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Consequences of NMDA receptor deficiency can be rescued in the adult brain

Molecular psychiatry, 2021-07, Vol.26 (7), p.2929-2942

2021

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Chronic social isolation exerts opposing sex-specific consequences on serotonin neuronal excitability and behaviour

Neuropharmacology, 2020-05, Vol.168, p.108015, Article 108015

2020

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Serotonin Regulation of the Prefrontal Cortex: Cognitive Relevance and the Impact of Developmental Perturbation

ACS chemical neuroscience, 2019-07, Vol.10 (7), p.3078-3093

2019

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Ready, set, go: the bridging of attention to action by acetylcholine in prefrontal cortex

The Journal of physiology, 2018-05, Vol.596 (9), p.1539-1540

2018

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Impaired Cholinergic Excitation of Prefrontal Attention Circuitry in the TgCRND8 Model of Alzheimer's Disease

The Journal of neuroscience, 2015-09, Vol.35 (37), p.12779-12791

2015

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Ventral hippocampal cholecystokinin interneurons gate contextual reward memory

iScience, 2024-02, Vol.27 (2), p.108824-108824, Article 108824

2024

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Enhanced Function of Prefrontal Serotonin 5-HT2 Receptors in a Rat Model of Psychiatric Vulnerability

The Journal of neuroscience, 2010-09, Vol.30 (36), p.12138-12150

2010

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Dual recombinase fate mapping reveals a transient cholinergic phenotype in multiple populations of developing glutamatergic neurons

Journal of comparative neurology (1911), 2020-02, Vol.528 (2), p.283-307

2020

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Mapping the physiological and molecular markers of stress and SSRI antidepressant treatment in S100a10 corticostriatal neurons

Molecular psychiatry, 2020-05, Vol.25 (5), p.1112-1129

2020

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Chrna5 and lynx prototoxins identify acetylcholine super-responder subplate neurons

iScience, 2023-02, Vol.26 (2), p.105992-105992, Article 105992

2023

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CHRNA5 links chandelier cells to severity of amyloid pathology in aging and Alzheimer's disease

Translational psychiatry, 2024-02, Vol.14 (1), p.83-83, Article 83

2024

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Opposing Cholinergic and Serotonergic Modulation of Layer 6 in Prefrontal Cortex

Frontiers in neural circuits, 2018-01, Vol.11, p.107-107

2018

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George Aghajanian (1932–2023)

Chrna5 is Essential for a Rapid and Protected Response to Optogenetic Release of Endogenous Acetylcholine in Prefrontal Cortex

Xanomeline restores endogenous nicotinic acetylcholine receptor signaling in mouse prefrontal cortex

Median raphe serotonin neurons promote anxiety-like behavior via inputs to the dorsal hippocampus

Cholecystokinin-Expressing Interneurons of the Medial Prefrontal Cortex Mediate Working Memory Retrieval

Chronic social isolation reduces 5-HT neuronal activity via upregulated SK3 calcium-activated potassium channels

Deficits in integrative NMDA receptors caused by Grin1 disruption can be rescued in adulthood

Hippocampal 5-HT Input Regulates Memory Formation and Schaffer Collateral Excitation

Chrna5-Expressing Neurons in the Interpeduncular Nucleus Mediate Aversion Primed by Prior Stimulation or Nicotine Exposure

Schizophrenia susceptibility pathway neuregulin 1-ErbB4 suppresses Src upregulation of NMDA receptors

Postnatal day 2 to 11 constitutes a 5-HT-sensitive period impacting adult mPFC function

Dorsal raphe serotonin neurons inhibit operant responding for reward via inputs to the ventral tegmental area but not the nucleus accumbens: evidence from studies combining optogenetic stimulation and serotonin reuptake inhibition

Serotonin receptor expression in human prefrontal cortex: balancing excitation and inhibition across postnatal development

Consequences of NMDA receptor deficiency can be rescued in the adult brain

Chronic social isolation exerts opposing sex-specific consequences on serotonin neuronal excitability and behaviour

Serotonin Regulation of the Prefrontal Cortex: Cognitive Relevance and the Impact of Developmental Perturbation

Ready, set, go: the bridging of attention to action by acetylcholine in prefrontal cortex

Impaired Cholinergic Excitation of Prefrontal Attention Circuitry in the TgCRND8 Model of Alzheimer's Disease

Ventral hippocampal cholecystokinin interneurons gate contextual reward memory

Enhanced Function of Prefrontal Serotonin 5-HT2 Receptors in a Rat Model of Psychiatric Vulnerability

Dual recombinase fate mapping reveals a transient cholinergic phenotype in multiple populations of developing glutamatergic neurons

Mapping the physiological and molecular markers of stress and SSRI antidepressant treatment in S100a10 corticostriatal neurons

Chrna5 and lynx prototoxins identify acetylcholine super-responder subplate neurons

CHRNA5 links chandelier cells to severity of amyloid pathology in aging and Alzheimer's disease

Opposing Cholinergic and Serotonergic Modulation of Layer 6 in Prefrontal Cortex

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