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Generation, purification and transplantation of photoreceptors derived from human induced pluripotent stem cells

PloS one, 2010-01, Vol.5 (1), p.e8763-e8763

2010

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Transplantation of Human Embryonic Stem Cell-Derived Photoreceptors Restores Some Visual Function in Crx-Deficient Mice

Cell stem cell, 2009-01, Vol.4 (1), p.73-79

2009

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Immune modulation by MANF promotes tissue repair and regenerative success in the retina

Science (American Association for the Advancement of Science), 2016-07, Vol.353 (6294), p.43-43

2016

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Dpp/TGFβ-superfamily play a dual conserved role in mediating the damage response in the retina

PloS one, 2021-10, Vol.16 (10), p.e0258872-e0258872

2021

Volltextzugriff (PDF)

Efficient Generation of Retinal Progenitor Cells from Human Embryonic Stem Cells

Proceedings of the National Academy of Sciences - PNAS, 2006-08, Vol.103 (34), p.12769-12774

2006

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Guiding the morphogenesis of dissociated newborn mouse retinal cells and hES cell-derived retinal cells by soft lithography-patterned microchannel PLGA scaffolds

Biomaterials, 2012-02, Vol.33 (5), p.1396-1405

2012

Volltextzugriff (PDF)

Genome-wide analysis of Müller glial differentiation reveals a requirement for Notch signaling in postmitotic cells to maintain the glial fate

PloS one, 2011, Vol.6 (8), p.e22817-e22817

2011

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Disease modeling and pharmacological rescue of autosomal dominant retinitis pigmentosa associated with RHO copy number variation

eLife, 2024-04, Vol.12

2024

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Blimp1 controls photoreceptor versus bipolar cell fate choice during retinal development

Development (Cambridge), 2010-02, Vol.137 (4), p.619-629

2010

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Strategies for retinal repair: cell replacement and regeneration

Progress in Brain Research, 2009, Vol.175, p.23-31

2009

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Histone Deacetylase Inhibition Elicits an Evolutionarily Conserved Self-Renewal Program in Embryonic Stem Cells

Cell stem cell, 2009-04, Vol.4 (4), p.359-369

2009

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Immunosuppression via Loss of IL2rγ Enhances Long-Term Functional Integration of hESC-Derived Photoreceptors in the Mouse Retina

Cell stem cell, 2017-03, Vol.20 (3), p.374-384.e5

2017

Volltextzugriff (PDF)

Retinal Organoids: A Human Model System for Development, Diseases, and Therapies

Advances in experimental medicine and biology, 2023, Vol.1415, p.549-554

2023

Volltextzugriff (PDF)

Illustrating the potency of current Good Manufacturing Practice–compliant induced pluripotent stem cell lines as a source of multiple cell lineages using standardized protocols

Cytotherapy (Oxford, England), 2018-06, Vol.20 (6), p.861-872

2018

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Advancements in pre-clinical development of gene editing-based therapies to treat inherited retinal diseases

Vision research (Oxford), 2023-08, Vol.209, p.108257-108257, Article 108257

2023

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Biophysical, Molecular and Proteomic Profiling of Human Retinal Organoid-Derived Exosomes

Pharmaceutical research, 2023-04, Vol.40 (4), p.801-816

2023

Volltextzugriff (PDF)

Timed Notch Inhibition Drives Photoreceptor Fate Specification in Human Retinal Organoids

Investigative ophthalmology & visual science, 2022-09, Vol.63 (10), p.12-12

2022

Volltextzugriff (PDF)

Modeling the Dynamic AMD-Associated Chronic Oxidative Stress Changes in Human ESC and iPSC-Derived RPE Cells

Investigative ophthalmology & visual science, 2015-11, Vol.56 (12), p.7480-7488

2015

Volltextzugriff (PDF)

Hypoxia induces re‐entry of committed cells into pluripotency

Stem cells (Dayton, Ohio), 2013-09, Vol.31 (9), p.1737-1748

2013

Volltextzugriff (PDF)

Proteome and Secretome Dynamics of Human Retinal Pigment Epithelium in Response to Reactive Oxygen Species

Scientific reports, 2019-10, Vol.9 (1), p.15440-12, Article 15440

2019

Volltextzugriff (PDF)

Human embryonic stem cell applications for retinal degenerations

Experimental eye research, 2014-06, Vol.123, p.151-160

2014

Volltextzugriff (PDF)

Allele-specific gene editing to rescue dominant CRX-associated LCA7 phenotypes in a retinal organoid model

Stem cell reports, 2021-11, Vol.16 (11), p.2690-2702

2021

Volltextzugriff (PDF)

MANF delivery improves retinal homeostasis and cell replacement therapies in ageing mice

Experimental gerontology, 2020-06, Vol.134, p.110893-110893, Article 110893

2020

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An enhancer located in a Pde6c intron drives transient expression in the cone photoreceptors of developing mouse and human retinas

Developmental biology, 2022-08, Vol.488, p.131-150

2022

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DEPTOR Is a Stemness Factor That Regulates Pluripotency of Embryonic Stem Cells

The Journal of biological chemistry, 2014-11, Vol.289 (46), p.31818-31826

2014

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Generation, purification and transplantation of photoreceptors derived from human induced pluripotent stem cells

Transplantation of Human Embryonic Stem Cell-Derived Photoreceptors Restores Some Visual Function in Crx-Deficient Mice

Immune modulation by MANF promotes tissue repair and regenerative success in the retina

Dpp/TGFβ-superfamily play a dual conserved role in mediating the damage response in the retina

Efficient Generation of Retinal Progenitor Cells from Human Embryonic Stem Cells

Guiding the morphogenesis of dissociated newborn mouse retinal cells and hES cell-derived retinal cells by soft lithography-patterned microchannel PLGA scaffolds

Genome-wide analysis of Müller glial differentiation reveals a requirement for Notch signaling in postmitotic cells to maintain the glial fate

Disease modeling and pharmacological rescue of autosomal dominant retinitis pigmentosa associated with RHO copy number variation

Blimp1 controls photoreceptor versus bipolar cell fate choice during retinal development

Strategies for retinal repair: cell replacement and regeneration

Histone Deacetylase Inhibition Elicits an Evolutionarily Conserved Self-Renewal Program in Embryonic Stem Cells

Immunosuppression via Loss of IL2rγ Enhances Long-Term Functional Integration of hESC-Derived Photoreceptors in the Mouse Retina

Retinal Organoids: A Human Model System for Development, Diseases, and Therapies

Illustrating the potency of current Good Manufacturing Practice–compliant induced pluripotent stem cell lines as a source of multiple cell lineages using standardized protocols

Advancements in pre-clinical development of gene editing-based therapies to treat inherited retinal diseases

Biophysical, Molecular and Proteomic Profiling of Human Retinal Organoid-Derived Exosomes

Timed Notch Inhibition Drives Photoreceptor Fate Specification in Human Retinal Organoids

Modeling the Dynamic AMD-Associated Chronic Oxidative Stress Changes in Human ESC and iPSC-Derived RPE Cells

Hypoxia induces re‐entry of committed cells into pluripotency

Proteome and Secretome Dynamics of Human Retinal Pigment Epithelium in Response to Reactive Oxygen Species

Human embryonic stem cell applications for retinal degenerations

Allele-specific gene editing to rescue dominant CRX-associated LCA7 phenotypes in a retinal organoid model

MANF delivery improves retinal homeostasis and cell replacement therapies in ageing mice

An enhancer located in a Pde6c intron drives transient expression in the cone photoreceptors of developing mouse and human retinas

DEPTOR Is a Stemness Factor That Regulates Pluripotency of Embryonic Stem Cells

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