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Toward the Combinatorial Selection of Chemically Modified DNAzyme RNase A Mimics Active Against all-RNA Substrates

ACS combinatorial science, 2013-04, Vol.15 (4), p.174-182

2013

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Synthesis and Enzymatic Incorporation of Modified Deoxyuridine Triphosphates

Molecules (Basel, Switzerland), 2015-07, Vol.20 (8), p.13591-13602

2015

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A densely modified M2+-independent DNAzyme that cleaves RNA efficiently with multiple catalytic turnover

Chemical science (Cambridge), 2018-02, Vol.9 (7), p.1813-1821

2018

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Crystal structures of thrombin in complex with chemically modified thrombin DNA aptamers reveal the origins of enhanced affinity

Nucleic acids research, 2018-05, Vol.46 (9), p.4819-4830

2018

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Whole cell-SELEX of aptamers with a tyrosine-like side chain against live bacteria

Organic & biomolecular chemistry, 2017-03, Vol.15 (9), p.1980-1989

2017

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Selection of PD1/PD-L1 X-Aptamers

Biochimie, 2018-02, Vol.145, p.125-130

2018

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Protein-inspired modified DNAzymes: dramatic effects of shortening side-chain length of 8-imidazolyl modified deoxyadenosines in selecting RNaseA mimicking DNAzymes

Organic & biomolecular chemistry, 2011-01, Vol.9 (7), p.2266-2273

2011

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A self-cleaving DNA enzyme modified with amines, guanidines and imidazoles operates independently of divalent metal cations (M2+)

Nucleic acids research, 2009-04, Vol.37 (5), p.1638-1649

2009

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A densely modified M 2+ -independent DNAzyme that cleaves RNA efficiently with multiple catalytic turnover

Chemical science (Cambridge), 2018-02, Vol.9 (7), p.1813-1821

2018

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Systematic study of constraints imposed by modified nucleoside triphosphates with protein-like side chains for use in in vitro selection

Organic & biomolecular chemistry, 2017, Vol.15 (3), p.610-618

2017

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X-Aptamer Selection and Validation

Methods in molecular biology (Clifton, N.J.), 2017-01, Vol.1632, p.151

2017

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DNAzyme with Three Protein-Like Functional Groups: Enhancing Catalytic Efficiency of M²⁺-Independent RNA Cleavage

Chembiochem : a European journal of chemical biology, 2009-08, Vol.10 (12), p.1988-1992

2009

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Introduction of guanidinium-modified deoxyuridine into the substrate binding regions of DNAzyme 10–23 to enhance target affinity: Implications for DNAzyme design

Bioorganic & medicinal chemistry letters, 2010-09, Vol.20 (17), p.5119-5122

2010

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A divalent metal-dependent self-cleaving DNAzyme with a tyrosine side chain

Organic & biomolecular chemistry, 2011-10, Vol.9 (20), p.6949-6954

2011

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A densely modified M2+-independent DNAzyme that cleaves RNA efficiently with multiple catalytic turnoverElectronic supplementary information (ESI) available. See DOI: 10.1039/c7sc04491g

2018-02

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A densely modified M2+-independent DNAzyme that cleaves RNA efficiently with multiple catalytic turnover† †Electronic supplementary information (ESI) available. See DOI: 10.1039/c7sc04491g

Chemical science (Cambridge), 2018-01, Vol.9 (7), p.1813-1821

2018

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Whole cell-SELEX of aptamers with a tyrosine-like side chain against live bacteriaElectronic supplementary information (ESI) available: Tables and figures presenting the selection conditions, the enrichment numbers, the sequencing data and the raw data for the selectivity and saturation binding assays. See DOI: 10.1039/c6ob02451c

2017-03

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140. Non-SELEX Bead-Based X-Aptamer Selection

Molecular therapy, 2015-05, Vol.23, p.S57-S57

2015

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Systematic study of constraints imposed by modified nucleoside triphosphates with protein-like side chains for use in in vitro selectionElectronic supplementary information (ESI) available. See DOI: 10.1039/c6ob02335e

2017-01

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A DNAzyme with Three Protein‐Like Functional Groups: Enhancing Catalytic Efficiency of M 2+ ‐Independent RNA Cleavage

Chembiochem : a European journal of chemical biology, 2009-08, Vol.10 (12), p.1988-1992

2009

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Elevated Steady State WBC and Platelet Counts Are Associated with Frequent Emergency Room Use in Adults with Sickle Cell Anemia

PloS one, 2015-08, Vol.10 (8), p.e0133116-e0133116

2015

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Impact of comorbidities in severely injured patients with blunt chest injury: A population-based retrospective cohort study

Injury, 2024-06, Vol.55 (6), p.111538-111538, Article 111538

2024

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Alterations in the gut microbiome implicate key taxa and metabolic pathways across inflammatory arthritis phenotypes

Science translational medicine, 2023-07, Vol.15 (706), p.eabn4722

2023

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Risk factors for second acute myeloid leukemia/myelodysplastic syndrome among survivors of non-Hodgkin lymphoma

Leukemia, 2016-05, Vol.30 (5), p.1187-1190

2016

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Risk Factors for Melanoma Among Survivors of Non-Hodgkin Lymphoma

Journal of clinical oncology, 2015-10, Vol.33 (28), p.3096-3104

2015

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Toward the Combinatorial Selection of Chemically Modified DNAzyme RNase A Mimics Active Against all-RNA Substrates

Synthesis and Enzymatic Incorporation of Modified Deoxyuridine Triphosphates

A densely modified M2+-independent DNAzyme that cleaves RNA efficiently with multiple catalytic turnover

Crystal structures of thrombin in complex with chemically modified thrombin DNA aptamers reveal the origins of enhanced affinity

Whole cell-SELEX of aptamers with a tyrosine-like side chain against live bacteria

Selection of PD1/PD-L1 X-Aptamers

Protein-inspired modified DNAzymes: dramatic effects of shortening side-chain length of 8-imidazolyl modified deoxyadenosines in selecting RNaseA mimicking DNAzymes

A self-cleaving DNA enzyme modified with amines, guanidines and imidazoles operates independently of divalent metal cations (M2+)

A densely modified M 2+ -independent DNAzyme that cleaves RNA efficiently with multiple catalytic turnover

Systematic study of constraints imposed by modified nucleoside triphosphates with protein-like side chains for use in in vitro selection

X-Aptamer Selection and Validation

DNAzyme with Three Protein-Like Functional Groups: Enhancing Catalytic Efficiency of M²⁺-Independent RNA Cleavage

Introduction of guanidinium-modified deoxyuridine into the substrate binding regions of DNAzyme 10–23 to enhance target affinity: Implications for DNAzyme design

A divalent metal-dependent self-cleaving DNAzyme with a tyrosine side chain

A densely modified M2+-independent DNAzyme that cleaves RNA efficiently with multiple catalytic turnoverElectronic supplementary information (ESI) available. See DOI: 10.1039/c7sc04491g

A densely modified M2+-independent DNAzyme that cleaves RNA efficiently with multiple catalytic turnover† †Electronic supplementary information (ESI) available. See DOI: 10.1039/c7sc04491g

140. Non-SELEX Bead-Based X-Aptamer Selection

Systematic study of constraints imposed by modified nucleoside triphosphates with protein-like side chains for use in in vitro selectionElectronic supplementary information (ESI) available. See DOI: 10.1039/c6ob02335e

A DNAzyme with Three Protein‐Like Functional Groups: Enhancing Catalytic Efficiency of M 2+ ‐Independent RNA Cleavage

Elevated Steady State WBC and Platelet Counts Are Associated with Frequent Emergency Room Use in Adults with Sickle Cell Anemia

Impact of comorbidities in severely injured patients with blunt chest injury: A population-based retrospective cohort study

Alterations in the gut microbiome implicate key taxa and metabolic pathways across inflammatory arthritis phenotypes

Risk factors for second acute myeloid leukemia/myelodysplastic syndrome among survivors of non-Hodgkin lymphoma

Risk Factors for Melanoma Among Survivors of Non-Hodgkin Lymphoma

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