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Metabolic plasticity underpins innate and acquired resistance to LDHA inhibition

Nature chemical biology, 2016-10, Vol.12 (10), p.779

2016

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Lead optimization of a pyrazolo[1,5-a]pyrimidin-7(4H)-one scaffold to identify potent, selective and orally bioavailable KDM5 inhibitors suitable for in vivo biological studies

Bioorganic & medicinal chemistry letters, 2016-08, Vol.26 (16), p.4036-4041

2016

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Fragment-Based Discovery of a Selective and Cell-Active Benzodiazepinone CBP/EP300 Bromodomain Inhibitor (CPI-637)

ACS medicinal chemistry letters, 2016-05, Vol.7 (5), p.531-536

2016

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Numerical modeling of linear doping profiles for high-voltage thin-film SOI devices

IEEE transactions on electron devices, 1999-05, Vol.46 (5), p.1036-1041

1999

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GDC-9545 (Giredestrant): A Potent and Orally Bioavailable Selective Estrogen Receptor Antagonist and Degrader with an Exceptional Preclinical Profile for ER+ Breast Cancer

Journal of medicinal chemistry, 2021-08, Vol.64 (16), p.11841-11856

2021

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Antibody-mediated delivery of chimeric protein degraders which target estrogen receptor alpha (ERα)

Bioorganic & medicinal chemistry letters, 2020-02, Vol.30 (4), p.126907, Article 126907

2020

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From a novel HTS hit to potent, selective, and orally bioavailable KDM5 inhibitors

Bioorganic & medicinal chemistry letters, 2017-07, Vol.27 (13), p.2974-2981

2017

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Discovery of a C-8 hydroxychromene as a potent degrader of estrogen receptor alpha with improved rat oral exposure over GDC-0927

Bioorganic & medicinal chemistry letters, 2019-08, Vol.29 (16), p.2090-2093

2019

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Discovery of GNE-502 as an orally bioavailable and potent degrader for estrogen receptor positive breast cancer

Bioorganic & medicinal chemistry letters, 2021-10, Vol.50, p.128335-128335, Article 128335

2021

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Unexpected equivalent potency of a constrained chromene enantiomeric pair rationalized by co-crystal structures in complex with estrogen receptor alpha

Bioorganic & medicinal chemistry letters, 2019-04, Vol.29 (7), p.905-911

2019

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From a novel HTS hit to potent, selective, and orally bioavailable KDM5 inhibitors

Bioorganic & medicinal chemistry letters, 2017-07, Vol.27 (13)

2017

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Prevention and management of hepatitis B virus reactivation in patients with hematological malignancies treated with anticancer therapy

World journal of gastroenterology : WJG, 2016-07, Vol.22 (28), p.6484-6500

2016

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Infrared authentication of ginseng species: the use of the 2-6PC rule

Journal of AOAC International, 2009-03, Vol.92 (2), p.672

2009

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Performance of the 2017 European Alliance of Associations for Rheumatology/American College of Rheumatology Classification Criteria in Patients With Idiopathic Inflammatory Myopathy and Anti–Melanoma Differentiation–Associated Protein 5 Positivity

Arthritis & rheumatology (Hoboken, N.J.), 2022-09, Vol.74 (9), p.1588-1592

2022

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Molecular characterization of the fecal microbiota in patients with nonalcoholic steatohepatitis--a longitudinal study

PloS one, 2013-04, Vol.8 (4), p.e62885-e62885

2013

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Molecular Identification of Spirometra erinaceieuropaei Tapeworm in Cases of Human Sparganosis, Hong Kong

Emerging infectious diseases, 2017-04, Vol.23 (4), p.665-668

2017

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Nance-Horan Syndrome-like 1 protein negatively regulates Scar/WAVE-Arp2/3 activity and inhibits lamellipodia stability and cell migration

Nature communications, 2021-09, Vol.12 (1), p.5687-5687, Article 5687

2021

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Oseltamivir- and amantadine-resistant influenza viruses A (H1N1)

Emerging infectious diseases, 2009-06, Vol.15 (6), p.966-968

2009

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Systematic Review on Therapeutic Strategies to Minimize Corneal Stromal Scarring After Injury

Eye & contact lens, 2019-11, Vol.45 (6), p.347

2019

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Five-year cardiovascular event risk in early rheumatoid arthritis patients who received treat-to-target management: a case-control study

Rheumatology (Oxford, England), 2023-09, Vol.62 (9), p.2998-3005

2023

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Predictors of rapidly progressive- interstitial lung disease and mortality in patients with autoantibodies against melanoma differentiation-associated protein 5 dermatomyositis

Rheumatology (Oxford, England), 2022-11, Vol.61 (11), p.4437-4444

2022

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Comparison of two novel swept-source optical coherence tomography devices to a partial coherence interferometry-based biometer

Scientific reports, 2021-07, Vol.11 (1), p.14853-14853, Article 14853

2021

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Vision Transformers (ViT) for Blanket-Penetrating Sleep Posture Recognition Using a Triple Ultra-Wideband (UWB) Radar System

Sensors (Basel, Switzerland), 2023-02, Vol.23 (5), p.2475

2023

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Nurse‐Led Consultation for Patients With Rheumatoid Arthritis at Low Disease Activity: A Randomized Noninferiority Trial

Arthritis care & research (2010), 2022-10, Vol.74 (10), p.1736-1744

2022

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Metabolic plasticity underpins innate and acquired resistance to LDHA inhibition

Lead optimization of a pyrazolo[1,5-a]pyrimidin-7(4H)-one scaffold to identify potent, selective and orally bioavailable KDM5 inhibitors suitable for in vivo biological studies

Fragment-Based Discovery of a Selective and Cell-Active Benzodiazepinone CBP/EP300 Bromodomain Inhibitor (CPI-637)

Numerical modeling of linear doping profiles for high-voltage thin-film SOI devices

GDC-9545 (Giredestrant): A Potent and Orally Bioavailable Selective Estrogen Receptor Antagonist and Degrader with an Exceptional Preclinical Profile for ER+ Breast Cancer

Antibody-mediated delivery of chimeric protein degraders which target estrogen receptor alpha (ERα)

From a novel HTS hit to potent, selective, and orally bioavailable KDM5 inhibitors

Discovery of a C-8 hydroxychromene as a potent degrader of estrogen receptor alpha with improved rat oral exposure over GDC-0927

Discovery of GNE-502 as an orally bioavailable and potent degrader for estrogen receptor positive breast cancer

Unexpected equivalent potency of a constrained chromene enantiomeric pair rationalized by co-crystal structures in complex with estrogen receptor alpha

From a novel HTS hit to potent, selective, and orally bioavailable KDM5 inhibitors

Abstract A20: A leukemic model of acquired resistance to BET inhibition reveals a role for CBP/EP300 bromodomains in the regulation of c-MYC expression

Prevention and management of hepatitis B virus reactivation in patients with hematological malignancies treated with anticancer therapy

Infrared authentication of ginseng species: the use of the 2-6PC rule

Performance of the 2017 European Alliance of Associations for Rheumatology/American College of Rheumatology Classification Criteria in Patients With Idiopathic Inflammatory Myopathy and Anti–Melanoma Differentiation–Associated Protein 5 Positivity

Molecular characterization of the fecal microbiota in patients with nonalcoholic steatohepatitis--a longitudinal study

Molecular Identification of Spirometra erinaceieuropaei Tapeworm in Cases of Human Sparganosis, Hong Kong

Nance-Horan Syndrome-like 1 protein negatively regulates Scar/WAVE-Arp2/3 activity and inhibits lamellipodia stability and cell migration

Oseltamivir- and amantadine-resistant influenza viruses A (H1N1)

Systematic Review on Therapeutic Strategies to Minimize Corneal Stromal Scarring After Injury

Five-year cardiovascular event risk in early rheumatoid arthritis patients who received treat-to-target management: a case-control study

Predictors of rapidly progressive- interstitial lung disease and mortality in patients with autoantibodies against melanoma differentiation-associated protein 5 dermatomyositis

Comparison of two novel swept-source optical coherence tomography devices to a partial coherence interferometry-based biometer

Vision Transformers (ViT) for Blanket-Penetrating Sleep Posture Recognition Using a Triple Ultra-Wideband (UWB) Radar System

Nurse‐Led Consultation for Patients With Rheumatoid Arthritis at Low Disease Activity: A Randomized Noninferiority Trial

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