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Novel Co-crystal of Pentoxifylline and Protocatechuic Acid Relieves Allodynia in Rat Models of Peripheral Neuropathic Pain and CRPS by Alleviating Local Tissue Hypoxia

ACS chemical neuroscience, 2021-10, Vol.12 (20), p.3855-3863

2021

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The emergence of animal models of chronic pain and logistical and methodological issues concerning their use

Journal of Neural Transmission, 2020-04, Vol.127 (4), p.393-406

2020

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Spinal intracellular metabotropic glutamate receptor 5 (mGluR5) contributes to pain and c-fos expression in a rat model of inflammatory pain

Pain (Amsterdam), 2017-04, Vol.158 (4), p.705-716

2017

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Intracellular mGluR5 plays a critical role in neuropathic pain

Nature communications, 2016-02, Vol.7 (1), p.10604-10604, Article 10604

2016

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Sex differences in the contributions of spinal atypical PKCs and downstream targets to the maintenance of nociceptive sensitization

Molecular pain, 2019-01, Vol.15, p.1744806919840582-1744806919840582

2019

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The effect of a topical combination of clonidine and pentoxifylline on post-traumatic neuropathic pain patients: study protocol for a randomized, double-blind placebo-controlled trial

Trials, 2021-02, Vol.22 (1), p.149-149, Article 149

2021

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Recurrent hypoxemia in children is associated with increased analgesic sensitivity to opiates

Anesthesiology (Philadelphia), 2006-10, Vol.105 (4), p.665-669

2006

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A Cyclic Tetrapeptide (“Cyclodal”) and Its Mirror-Image Isomer Are Both High-Affinity μ Opioid Receptor Antagonists

Journal of medicinal chemistry, 2016-10, Vol.59 (19), p.9243-9254

2016

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Drug-Nutraceutical Co-Crystal and Salts for Making New and Improved Bi-Functional Analgesics

Pharmaceutics, 2020-11, Vol.12 (12), p.1144

2020

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Consistent sex-dependent effects of PKMζ gene ablation and pharmacological inhibition on the maintenance of referred pain

Molecular pain, 2016, Vol.12

2016

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Role of NFκB in an Animal Model of Complex Regional Pain Syndrome–type I (CRPS-I)

The journal of pain, 2009-11, Vol.10 (11), p.1161-1169

2009

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Glycemia-dependent Nuclear Factor κB Activation Contributes to Mechanical Allodynia in Rats with Chronic Postischemia Pain

Anesthesiology (Philadelphia), 2013-09, Vol.119 (3), p.687-697

2013

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Recurrent hypoxemia in young children with obstructive sleep apnea is associated with reduced opioid requirement for analgesia

Anesthesiology (Philadelphia), 2004-04, Vol.100 (4), p.806-810

2004

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Recurrent hypoxia in rats during development increases subsequent respiratory sensitivity to fentanyl

Anesthesiology (Philadelphia), 2006-10, Vol.105 (4), p.715-718

2006

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The Bifunctional μ Opioid Agonist/Antioxidant [Dmt1]DALDA Is a Superior Analgesic in an Animal Model of Complex Regional Pain Syndrome-Type I

ACS chemical neuroscience, 2015-11, Vol.6 (11), p.1789-1793

2015

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Effects of topical combinations of clonidine and pentoxifylline on capsaicin-induced allodynia and postcapsaicin tourniquet-induced pain in healthy volunteers: a double-blind, randomized, controlled study

Pain (Amsterdam), 2016-10, Vol.157 (10), p.2366-2374

2016

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Topical Combinations to Treat Microvascular Dysfunction of Chronic Postischemia Pain

Anesthesia and analgesia, 2014-04, Vol.118 (4), p.830-840

2014

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Effects of Glycemic Regulation on Chronic Postischemia Pain

Anesthesiology (Philadelphia), 2011-09, Vol.115 (3), p.614-625

2011

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Topical Combinations Aimed at Treating Microvascular Dysfunction Reduce Allodynia in Rat Models of CRPS-I and Neuropathic Pain

The journal of pain, 2013, Vol.14 (1), p.66-78

2013

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Analgesic Nutraceutical Salts and Co-crystals of Pentoxifylline, Clonidine and Linsidomine for the Topical Treatment of Complex Regional Pain Syndrome-1 (1141)

Neurology, 2020-04, Vol.94 (15_supplement)

2020

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Long-term recurrent hypoxia in developing rat attenuates respiratory responses to subsequent acute hypoxia

Pediatric research, 2006-04, Vol.59 (4), p.525-530

2006

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Neurokinin-1 versus mu-opioid receptor binding in rat nucleus tractus solitarius after single and recurrent intermittent hypoxia

Brain research bulletin, 2003-01, Vol.59 (4), p.307-313

2003

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Respiratory responses to intermittent hypoxia in unsedated piglets: relation to substance P binding in brainstem

Respiratory physiology & neurobiology, 2004-10, Vol.143 (1), p.21-35

2004

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Pentoxifylline reduces chronic post-ischemia pain by alleviating microvascular dysfunction

European journal of pain, 2013-07, Vol.18 (3), p.406-414

2013

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Carotenoid biosynthesis: isolation and characterization of a bifunctional enzyme catalyzing the synthesis of phytoene

Proceedings of the National Academy of Sciences - PNAS, 1988-10, Vol.85 (19), p.7054-7058

1988

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Novel Co-crystal of Pentoxifylline and Protocatechuic Acid Relieves Allodynia in Rat Models of Peripheral Neuropathic Pain and CRPS by Alleviating Local Tissue Hypoxia

The emergence of animal models of chronic pain and logistical and methodological issues concerning their use

Spinal intracellular metabotropic glutamate receptor 5 (mGluR5) contributes to pain and c-fos expression in a rat model of inflammatory pain

Intracellular mGluR5 plays a critical role in neuropathic pain

Sex differences in the contributions of spinal atypical PKCs and downstream targets to the maintenance of nociceptive sensitization

The effect of a topical combination of clonidine and pentoxifylline on post-traumatic neuropathic pain patients: study protocol for a randomized, double-blind placebo-controlled trial

Recurrent hypoxemia in children is associated with increased analgesic sensitivity to opiates

A Cyclic Tetrapeptide (“Cyclodal”) and Its Mirror-Image Isomer Are Both High-Affinity μ Opioid Receptor Antagonists

Drug-Nutraceutical Co-Crystal and Salts for Making New and Improved Bi-Functional Analgesics

Consistent sex-dependent effects of PKMζ gene ablation and pharmacological inhibition on the maintenance of referred pain

Role of NFκB in an Animal Model of Complex Regional Pain Syndrome–type I (CRPS-I)

Glycemia-dependent Nuclear Factor κB Activation Contributes to Mechanical Allodynia in Rats with Chronic Postischemia Pain

Recurrent hypoxemia in young children with obstructive sleep apnea is associated with reduced opioid requirement for analgesia

Recurrent hypoxia in rats during development increases subsequent respiratory sensitivity to fentanyl

The Bifunctional μ Opioid Agonist/Antioxidant [Dmt1]DALDA Is a Superior Analgesic in an Animal Model of Complex Regional Pain Syndrome-Type I

Effects of topical combinations of clonidine and pentoxifylline on capsaicin-induced allodynia and postcapsaicin tourniquet-induced pain in healthy volunteers: a double-blind, randomized, controlled study

Topical Combinations to Treat Microvascular Dysfunction of Chronic Postischemia Pain

Effects of Glycemic Regulation on Chronic Postischemia Pain

Topical Combinations Aimed at Treating Microvascular Dysfunction Reduce Allodynia in Rat Models of CRPS-I and Neuropathic Pain

Analgesic Nutraceutical Salts and Co-crystals of Pentoxifylline, Clonidine and Linsidomine for the Topical Treatment of Complex Regional Pain Syndrome-1 (1141)

Long-term recurrent hypoxia in developing rat attenuates respiratory responses to subsequent acute hypoxia

Neurokinin-1 versus mu-opioid receptor binding in rat nucleus tractus solitarius after single and recurrent intermittent hypoxia

Respiratory responses to intermittent hypoxia in unsedated piglets: relation to substance P binding in brainstem

Pentoxifylline reduces chronic post-ischemia pain by alleviating microvascular dysfunction

Carotenoid biosynthesis: isolation and characterization of a bifunctional enzyme catalyzing the synthesis of phytoene

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