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Differential Effects of Omeprazole and Pantoprazole on the Pharmacodynamics and Pharmacokinetics of Clopidogrel in Healthy Subjects: Randomized, Placebo-Controlled, Crossover Comparison Studies

Clinical pharmacology and therapeutics, 2011-01, Vol.89 (1), p.65-74

2011

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Effects of rifampin and mefenamic acid on the pharmacokinetics and pharmacodynamics of dapagliflozin

Diabetes, obesity & metabolism, 2013-03, Vol.15 (3), p.280-283

2013

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Pharmacokinetics and pharmacodynamics of dapagliflozin, a novel selective inhibitor of sodium-glucose co-transporter type 2, in Japanese subjects without and with type 2 diabetes mellitus

Diabetes, obesity & metabolism, 2011-04, Vol.13 (4), p.357-365

2011

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Lack of pharmacokinetic interaction between dapagliflozin, a novel sodium-glucose transporter 2 inhibitor, and metformin, pioglitazone, glimepiride or sitagliptin in healthy subjects

Diabetes, obesity & metabolism, 2011, Vol.13 (1), p.47-54

2011

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Phase I trial of buthionine sulfoximine in combination with melphalan in patients with cancer

Journal of clinical oncology, 1996-01, Vol.14 (1), p.249-256

1996

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Effect of a high-fat meal on the pharmacokinetics of dapagliflozin, a selective SGLT2 inhibitor, in healthy subjects

Diabetes, obesity & metabolism, 2011-08, Vol.13 (8), p.770-773

2011

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Effect of saxagliptin on the pharmacokinetics of the active components of Ortho-Cyclen®, a combined oral contraceptive containing ethinyl estradiol and norgestimate, in healthy women

Diabetes, obesity & metabolism, 2012-12, Vol.14 (12), p.1155-1157

2012

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A Dose-Escalation Study of the Safety, Tolerability, and Pharmacokinetics of Intravenous Gatifloxacin in Healthy Adult Men

Pharmacotherapy, 2000-06, Vol.20 (6P2), p.49S-58S

2000

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Depletion of Glutathione in Normal and Malignant Human Cells In Vivo by Buthionine Sulfoximine: Clinical and Biochemical Results

JNCI : Journal of the National Cancer Institute, 1992-02, Vol.84 (4), p.264-267

1992

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Effect of Multiple-Dose Gatifloxacin or Ciprofloxacin on Glucose Homeostasis and Insulin Production in Patients with Noninsulin-Dependent Diabetes Mellitus Maintained with Diet and Exercise

Pharmacotherapy, 2000-06, Vol.20 (6P2), p.76S-86S

2000

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Phase I/pharmacokinetic study of topotecan by 24-hour continuous infusion weekly

Cancer research (Chicago, Ill.), 1994-03, Vol.54 (5), p.1220-1226

1994

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Phase I and pharmacokinetic study of ormaplatin (tetraplatin, NSC 363812) administered on a day 1 and day 8 schedule

Cancer research (Chicago, Ill.), 1994-02, Vol.54 (3), p.709-717

1994

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Open-Label, Nonrandomized Study of the Effects of Gatifloxacin on the Pharmacokinetics of Midazolam in Healthy Male Volunteers

Pharmacotherapy, 2000-03, Vol.20 (3), p.330-335

2000

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Enzymatic conjugation of chlorambucil with glutathione by human glutathione S-transferases and inhibition by ethacrynic acid

Biochemical pharmacology, 1991-09, Vol.42 (7), p.1504-1507

1991

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Interchangeability of 400-mg Intravenous and Oral Gatifloxacin in Healthy Adults

Pharmacotherapy, 2000-06, Vol.20 (6P2), p.59S-66S

2000

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Age and Gender Effects on the Pharmacokinetics of Gatifloxacin

Pharmacotherapy, 2000-06, Vol.20 (6P2), p.67S-75S

2000

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Characterization of glutathione S-transferase expression in lymphocytes from chronic lymphocytic leukemia patients

Cancer research (Chicago, Ill.), 1990-06, Vol.50 (12), p.3562-3568

1990

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Stereoselective pharmacokinetics of L-buthionine SR-sulfoximine in patients with cancer

Drug metabolism and disposition, 1994-11, Vol.22 (6), p.835

1994

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Phase I study of the mitomycin C analogue BMS-181174

British journal of cancer, 1998-06, Vol.77 (11), p.2020-2027

1998

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Pharmakokinetics and bioavailability study of ethacrynic acid as a modulator of drug resistance in patients with cancer

The Journal of pharmacology and experimental therapeutics, 1994-09, Vol.270 (3), p.1186

1994

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Safety and Pharmacokinetics of a Single Oral Dose of Gatifloxacin in Patients with Moderate to Severe Hepatic Impairment

Pharmacotherapy, 2000-06, Vol.20 (6P2), p.87S-94S

2000

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Phase I trial of thiotepa in combination with recombinant human granulocyte-macrophage colony-stimulating factor

Journal of clinical oncology, 1992-08, Vol.10 (8), p.1352-1358

1992

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Increased levels of glutathione S-transferase π transcript as a mechanism of resistance to ethacrynic acid

Biochemical journal, 1992, Vol.281 (1), p.219-224

1992

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Clinical, pharmacokinetic and biological studies of topotecan

Cancer chemotherapy and pharmacology, 1994-01, Vol.34 (S1), p.S46-S52

1994

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Phase I/pharmacokinetic/biochemical study of the nitroimadazole hypoxic cell sensitiser SR2508 (etanidazole) in combination with cyclophosphamide

British journal of cancer, 1993-10, Vol.68 (4), p.756-766

1993

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Differential Effects of Omeprazole and Pantoprazole on the Pharmacodynamics and Pharmacokinetics of Clopidogrel in Healthy Subjects: Randomized, Placebo-Controlled, Crossover Comparison Studies

Effects of rifampin and mefenamic acid on the pharmacokinetics and pharmacodynamics of dapagliflozin

Pharmacokinetics and pharmacodynamics of dapagliflozin, a novel selective inhibitor of sodium-glucose co-transporter type 2, in Japanese subjects without and with type 2 diabetes mellitus

Lack of pharmacokinetic interaction between dapagliflozin, a novel sodium-glucose transporter 2 inhibitor, and metformin, pioglitazone, glimepiride or sitagliptin in healthy subjects

Phase I trial of buthionine sulfoximine in combination with melphalan in patients with cancer

Effect of a high-fat meal on the pharmacokinetics of dapagliflozin, a selective SGLT2 inhibitor, in healthy subjects

Effect of saxagliptin on the pharmacokinetics of the active components of Ortho-Cyclen®, a combined oral contraceptive containing ethinyl estradiol and norgestimate, in healthy women

A Dose-Escalation Study of the Safety, Tolerability, and Pharmacokinetics of Intravenous Gatifloxacin in Healthy Adult Men

Depletion of Glutathione in Normal and Malignant Human Cells In Vivo by Buthionine Sulfoximine: Clinical and Biochemical Results

Effect of Multiple-Dose Gatifloxacin or Ciprofloxacin on Glucose Homeostasis and Insulin Production in Patients with Noninsulin-Dependent Diabetes Mellitus Maintained with Diet and Exercise

Phase I/pharmacokinetic study of topotecan by 24-hour continuous infusion weekly

Phase I and pharmacokinetic study of ormaplatin (tetraplatin, NSC 363812) administered on a day 1 and day 8 schedule

Open-Label, Nonrandomized Study of the Effects of Gatifloxacin on the Pharmacokinetics of Midazolam in Healthy Male Volunteers

Enzymatic conjugation of chlorambucil with glutathione by human glutathione S-transferases and inhibition by ethacrynic acid

Interchangeability of 400-mg Intravenous and Oral Gatifloxacin in Healthy Adults

Age and Gender Effects on the Pharmacokinetics of Gatifloxacin

Characterization of glutathione S-transferase expression in lymphocytes from chronic lymphocytic leukemia patients

Stereoselective pharmacokinetics of L-buthionine SR-sulfoximine in patients with cancer

Phase I study of the mitomycin C analogue BMS-181174

Pharmakokinetics and bioavailability study of ethacrynic acid as a modulator of drug resistance in patients with cancer

Safety and Pharmacokinetics of a Single Oral Dose of Gatifloxacin in Patients with Moderate to Severe Hepatic Impairment

Phase I trial of thiotepa in combination with recombinant human granulocyte-macrophage colony-stimulating factor

Increased levels of glutathione S-transferase π transcript as a mechanism of resistance to ethacrynic acid

Clinical, pharmacokinetic and biological studies of topotecan

Phase I/pharmacokinetic/biochemical study of the nitroimadazole hypoxic cell sensitiser SR2508 (etanidazole) in combination with cyclophosphamide

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