UB Paderborn / Katalog / Suche / in CDI

HIV-1 protease substrate-groove: Role in substrate recognition and inhibitor resistance

Biochimie, 2015-11, Vol.118, p.90-103

Laco, Gary S.

2015

Link zum Volltext

Verfügbarkeit prüfen

Phospholipid profiling of plasma from GW veterans and rodent models to identify potential biomarkers of Gulf War Illness

PloS one, 2017-04, Vol.12 (4), p.e0176634-e0176634

2017

Link zum Volltext

Verfügbarkeit prüfen

HIV-1 Gag Non-Cleavage Site PI Resistance Mutations Stabilize Protease/Gag Substrate Complexes In Silico via a Substrate-Clamp

BioChem, 2021-11, Vol.1 (3), p.190-209

Laco, Gary S.

2021

Link zum Volltext

Verfügbarkeit prüfen

Evaluation of two models for human topoisomerase I interaction with dsDNA and camptothecin derivatives

PloS one, 2011-08, Vol.6 (8), p.e24314-e24314

2011

Link zum Volltext

Verfügbarkeit prüfen

Mild TBI Results in a Long-Term Decrease in Circulating Phospholipids in a Mouse Model of Injury

Neuromolecular medicine, 2017-03, Vol.19 (1), p.122-135

2017

Link zum Volltext

Verfügbarkeit prüfen

Role of a tryptophan anchor in human topoisomerase I structure, function and inhibition

Biochemical journal, 2008-05, Vol.411 (3), p.523-530

2008

Link zum Volltext

Verfügbarkeit prüfen

Topoisomerase I inhibitors: selectivity and cellular resistance

Drug resistance updates, 1999-10, Vol.2 (5), p.307-318

1999

Link zum Volltext

Verfügbarkeit prüfen

Crystal Structure of Human T Cell Leukemia Virus Protease, a Novel Target for Anticancer Drug Design

Proceedings of the National Academy of Sciences - PNAS, 2005-12, Vol.102 (51), p.18332-18337

2005

Link zum Volltext

Verfügbarkeit prüfen

Interaction of Human Nuclear Topoisomerase I with Guanosine Quartet-forming and Guanosine-rich Single-stranded DNA and RNA Oligonucleotides

The Journal of biological chemistry, 2002-03, Vol.277 (11), p.8906-8911

2002

Link zum Volltext

Verfügbarkeit prüfen

Characterization of a novel topoisomerase I mutation from a camptothecin-resistant human prostate cancer cell line

Cancer research (Chicago, Ill.), 2001-03, Vol.61 (5), p.1964-1969

2001

Link zum Volltext

Verfügbarkeit prüfen

Human Topoisomerase I Inhibition: Docking Camptothecin and Derivatives into a Structure-Based Active Site Model

Biochemistry (Easton), 2002-02, Vol.41 (5), p.1428-1435

2002

Link zum Volltext

Verfügbarkeit prüfen

Position-Specific Trapping of Topoisomerase I-DNA Cleavage Complexes by Intercalated Benzo[a]-Pyrene Diol Epoxide Adducts at the 6-Amino Group of Adenine

Proceedings of the National Academy of Sciences - PNAS, 2000-09, Vol.97 (20), p.10739-10744

2000

Link zum Volltext

Verfügbarkeit prüfen

Different Effects on Human Topoisomerase I by Minor Groove and Intercalated Deoxyguanosine Adducts Derived from Two Polycyclic Aromatic Hydrocarbon Diol Epoxides at or Near a Normal Cleavage Site

The Journal of biological chemistry, 2002-04, Vol.277 (16), p.13666-13672

2002

Link zum Volltext

Verfügbarkeit prüfen

The Spleen Tyrosine Kinase (Syk) Regulates Alzheimer Amyloid-β Production and Tau Hyperphosphorylation

The Journal of biological chemistry, 2014-12, Vol.289 (49), p.33927-33944

2014

Link zum Volltext

Verfügbarkeit prüfen

Analysis of the S3 and S3′Subsite Specificities of Feline Immunodeficiency Virus (FIV) Protease: Development of a Broad-Based Protease Inhibitor Efficacious against FIV, SIV, and HIV in vitro and ex vivo

Proceedings of the National Academy of Sciences - PNAS, 1998-02, Vol.95 (3), p.939-944

1998

Link zum Volltext

Verfügbarkeit prüfen

Phosphorylation of DNA Topoisomerase I by the c-Abl Tyrosine Kinase Confers Camptothecin Sensitivity

The Journal of biological chemistry, 2004-12, Vol.279 (50), p.51851-51861

2004

Link zum Volltext

Verfügbarkeit prüfen

Retroviral proteases: correlating substrate recognition with both selected and native inhibitor resistance

Journal of molecular biochemistry, 2017-01, Vol.6 (2), p.45

Laco, Gary S

2017

Link zum Volltext

Verfügbarkeit prüfen

Activation of Camptothecin Derivatives by Conjugation to Triple Helix-Forming Oligonucleotides

Biochemistry (Easton), 2005-03, Vol.44 (11), p.4171-4180

2005

Link zum Volltext

Verfügbarkeit prüfen

Analysis of human topoisomerase I inhibition and interaction with the cleavage site +1 deoxyguanosine, via in vitro experiments and molecular modeling studies

Bioorganic & medicinal chemistry, 2004-10, Vol.12 (19), p.5225-5235

2004

Link zum Volltext

Verfügbarkeit prüfen

Crystal Structures of the Inactive D30N Mutant of Feline Immunodeficiency Virus Protease Complexed with a Substrate and an Inhibitor

Biochemistry (Easton), 1997-09, Vol.36 (35), p.10696-10708

1997

Link zum Volltext

Verfügbarkeit prüfen

Differential induction of topoisomerase I-DNA cleavage complexes by the indenoisoquinoline MJ-III-65 (NSC 706744) and camptothecin: Base sequence analysis and activity against camptothecin-resistant topoisomerases I

Cancer research (Chicago, Ill.), 2003-11, Vol.63 (21), p.7428-7435

2003

Link zum Volltext

Verfügbarkeit prüfen

Rice Tungro Bacilliform Virus Encodes Reverse Transcriptase, DNA Polymerase, and Ribonuclease H Activities

Proceedings of the National Academy of Sciences - PNAS, 1994-03, Vol.91 (7), p.2654-2658

1994

Link zum Volltext

Verfügbarkeit prüfen

Use of camptothecin-resistant mammalian cell lines to evaluate the role of topoisomerase I in the antiproliferative activity of the indolocarbazole, NB-506, and its topoisomerase I binding site

Cancer research (Chicago, Ill.), 2001-01, Vol.61 (2), p.504-508

2001

Link zum Volltext

Verfügbarkeit prüfen

Molecular replacement with pseudosymmetry and model dissimilarity: a case study

Acta crystallographica. Section D, Biological crystallography., 2006-02, Vol.62 (2), p.208-215

2006

Link zum Volltext

Verfügbarkeit prüfen

Structural studies of FIV and HIV-1 proteases complexed with an efficient inhibitor of FIV protease

Proteins, structure, function, and bioinformatics, 2000-01, Vol.38 (1), p.29-40

2000

Link zum Volltext

Verfügbarkeit prüfen

Menü

Weitere Dienste

Einstellungen

HIV-1 protease substrate-groove: Role in substrate recognition and inhibitor resistance

Phospholipid profiling of plasma from GW veterans and rodent models to identify potential biomarkers of Gulf War Illness

HIV-1 Gag Non-Cleavage Site PI Resistance Mutations Stabilize Protease/Gag Substrate Complexes In Silico via a Substrate-Clamp

Evaluation of two models for human topoisomerase I interaction with dsDNA and camptothecin derivatives

Mild TBI Results in a Long-Term Decrease in Circulating Phospholipids in a Mouse Model of Injury

Role of a tryptophan anchor in human topoisomerase I structure, function and inhibition

Topoisomerase I inhibitors: selectivity and cellular resistance

Crystal Structure of Human T Cell Leukemia Virus Protease, a Novel Target for Anticancer Drug Design

Interaction of Human Nuclear Topoisomerase I with Guanosine Quartet-forming and Guanosine-rich Single-stranded DNA and RNA Oligonucleotides

Characterization of a novel topoisomerase I mutation from a camptothecin-resistant human prostate cancer cell line

Human Topoisomerase I Inhibition: Docking Camptothecin and Derivatives into a Structure-Based Active Site Model

Position-Specific Trapping of Topoisomerase I-DNA Cleavage Complexes by Intercalated Benzo[a]-Pyrene Diol Epoxide Adducts at the 6-Amino Group of Adenine

Different Effects on Human Topoisomerase I by Minor Groove and Intercalated Deoxyguanosine Adducts Derived from Two Polycyclic Aromatic Hydrocarbon Diol Epoxides at or Near a Normal Cleavage Site

The Spleen Tyrosine Kinase (Syk) Regulates Alzheimer Amyloid-β Production and Tau Hyperphosphorylation

Analysis of the S3 and S3′Subsite Specificities of Feline Immunodeficiency Virus (FIV) Protease: Development of a Broad-Based Protease Inhibitor Efficacious against FIV, SIV, and HIV in vitro and ex vivo

Phosphorylation of DNA Topoisomerase I by the c-Abl Tyrosine Kinase Confers Camptothecin Sensitivity

Retroviral proteases: correlating substrate recognition with both selected and native inhibitor resistance

Activation of Camptothecin Derivatives by Conjugation to Triple Helix-Forming Oligonucleotides

Analysis of human topoisomerase I inhibition and interaction with the cleavage site +1 deoxyguanosine, via in vitro experiments and molecular modeling studies

Crystal Structures of the Inactive D30N Mutant of Feline Immunodeficiency Virus Protease Complexed with a Substrate and an Inhibitor

Differential induction of topoisomerase I-DNA cleavage complexes by the indenoisoquinoline MJ-III-65 (NSC 706744) and camptothecin: Base sequence analysis and activity against camptothecin-resistant topoisomerases I

Rice Tungro Bacilliform Virus Encodes Reverse Transcriptase, DNA Polymerase, and Ribonuclease H Activities

Use of camptothecin-resistant mammalian cell lines to evaluate the role of topoisomerase I in the antiproliferative activity of the indolocarbazole, NB-506, and its topoisomerase I binding site

Molecular replacement with pseudosymmetry and model dissimilarity: a case study

Structural studies of FIV and HIV-1 proteases complexed with an efficient inhibitor of FIV protease

Suchergebnisse filtern