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Targets for Drug Therapy for Autism Spectrum Disorder: Challenges and Future Directions

Journal of medicinal chemistry, 2017-11, Vol.60 (22), p.9114-9141

2017

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International Union of Basic and Clinical Pharmacology. CX. Classification of Receptors for 5-hydroxytryptamine; Pharmacology and Function

Pharmacological reviews, 2021-01, Vol.73 (1), p.310-520

2021

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σ2 Receptor and Its Role in Cancer with Focus on a MultiTarget Directed Ligand (MTDL) Approach

Molecules (Basel, Switzerland), 2021-06, Vol.26 (12), p.3743

2021

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Allosteric Modulators of Serotonin Receptors: A Medicinal Chemistry Survey

Pharmaceuticals (Basel, Switzerland), 2024-05, Vol.17 (6), p.695

2024

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Structure–Activity Relationships and Therapeutic Potentials of 5‑HT7 Receptor Ligands: An Update

Journal of medicinal chemistry, 2018-10, Vol.61 (19), p.8475-8503

2018

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The brain-penetrant 5-HT7 receptor agonist LP-211 reduces the sensory and affective components of neuropathic pain

Neurobiology of disease, 2017-10, Vol.106, p.214-221

2017

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Multitarget-Directed Ligands Hitting Serotonin Receptors: A Medicinal Chemistry Survey

Pharmaceuticals (Basel, Switzerland), 2024-09, Vol.17 (9), p.1238

2024

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5-HT7 Receptors Regulate Excitatory-Inhibitory Balance in Mouse Spinal Cord Dorsal Horn

Frontiers in molecular neuroscience, 2022-07, Vol.15, p.946159-946159

2022

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G-Protein Coupled Receptors Involved in the Resolution of Inflammation: Ligands and Therapeutic Perspectives

Mini reviews in medicinal chemistry, 2020-01, Vol.20 (20), p.2090-2103

2020

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The Formyl Peptide Receptor 2 as a Target for Promotion of Resolution of Inflammation

Current neuropharmacology, 2023-01, Vol.21 (7), p.1482-1487

2023

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Activation of 5-HT7 Serotonin Receptors Reverses Metabotropic Glutamate Receptor-Mediated Synaptic Plasticity in Wild-Type and Fmr1 Knockout Mice, a Model of Fragile X Syndrome

Biological psychiatry (1969), 2012-12, Vol.72 (11), p.924-933

2012

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Design and Synthesis of Arylpiperazine Serotonergic/Dopaminergic Ligands with Neuroprotective Properties

Molecules (Basel, Switzerland), 2022-02, Vol.27 (4), p.1297

2022

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Evaluating the effect of R-Baclofen and LP-211 on autistic behavior of the BTBR and Fmr1 -KO mouse models

Frontiers in neuroscience, 2023-03, Vol.17, p.1087788-1087788

2023

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Behavioral, Anti-Inflammatory, and Neuroprotective Effects of a Novel FPR2 Agonist in Two Mouse Models of Autism

Pharmaceuticals (Basel, Switzerland), 2022-01, Vol.15 (2), p.161

2022

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Low Basicity as a Characteristic for Atypical Ligands of Serotonin Receptor 5-HT2

International journal of molecular sciences, 2021-01, Vol.22 (3), p.1035

2021

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The 5-HT7 receptor triggers cerebellar long-term synaptic depression via PKC-MAPK

Neuropharmacology, 2016-02, Vol.101, p.426-438

2016

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5-HT1A receptor, an old target for new therapeutic agents

Current topics in medicinal chemistry, 2008-08, Vol.8 (12), p.1024-1034

2008

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The Contribution of Formyl Peptide Receptor Dysfunction to the Course of Neuroinflammation: A Potential Role in the Brain Pathology

Current neuropharmacology, 2020-01, Vol.18 (3), p.229-249

2020

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THE PROTECTIVE PROPERTIES OF NEW AGONISTS OF FPR2 ON THE EVOKED BY BACTERIAL ENDOTOXIN CHANGES: IN VITRO STUDY IN GLIAL CELLS

IBRO neuroscience reports, 2023-10, Vol.15, p.S214-S215

2023

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Mitochondrial Membranes of Human SH-SY5Y Neuroblastoma Cells Express Serotonin 5-HT7 Receptor

International journal of molecular sciences, 2020-12, Vol.21 (24), p.9629

2020

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Activation of Serotonin 5-HT7 Receptors Modulates Hippocampal Synaptic Plasticity by Stimulation of Adenylate Cyclases and Rescues Learning and Behavior in a Mouse Model of Fragile X Syndrome

Frontiers in molecular neuroscience, 2018-10, Vol.11, p.353-353

2018

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Time-Dependent Protective and Pro-Resolving Effects of FPR2 Agonists on Lipopolysaccharide-Exposed Microglia Cells Involve Inhibition of NF-κB and MAPKs Pathways

Cells (Basel, Switzerland), 2021-09, Vol.10 (9), p.2373

2021

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The brain-penetrant 5-HT 7 receptor agonist LP-211 reduces the sensory and affective components of neuropathic pain

Neurobiology of disease, 2017-10, Vol.106, p.214-221

2017

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LP-211 is a brain penetrant selective agonist for the serotonin 5-HT7 receptor

Neuroscience letters, 2010-08, Vol.481 (1), p.12-16

2010

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Microglia Depletion Attenuates the Pro-Resolving Activity of the Formyl Peptide Receptor 2 Agonist AMS21 Related to Inhibition of Inflammasome NLRP3 Signalling Pathway: A Study of Organotypic Hippocampal Cultures

Cells (Basel, Switzerland), 2023-11, Vol.12 (21), p.2570

2023

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Targets for Drug Therapy for Autism Spectrum Disorder: Challenges and Future Directions

International Union of Basic and Clinical Pharmacology. CX. Classification of Receptors for 5-hydroxytryptamine; Pharmacology and Function

σ2 Receptor and Its Role in Cancer with Focus on a MultiTarget Directed Ligand (MTDL) Approach

Allosteric Modulators of Serotonin Receptors: A Medicinal Chemistry Survey

Structure–Activity Relationships and Therapeutic Potentials of 5‑HT7 Receptor Ligands: An Update

The brain-penetrant 5-HT7 receptor agonist LP-211 reduces the sensory and affective components of neuropathic pain

Multitarget-Directed Ligands Hitting Serotonin Receptors: A Medicinal Chemistry Survey

5-HT7 Receptors Regulate Excitatory-Inhibitory Balance in Mouse Spinal Cord Dorsal Horn

G-Protein Coupled Receptors Involved in the Resolution of Inflammation: Ligands and Therapeutic Perspectives

The Formyl Peptide Receptor 2 as a Target for Promotion of Resolution of Inflammation

Activation of 5-HT7 Serotonin Receptors Reverses Metabotropic Glutamate Receptor-Mediated Synaptic Plasticity in Wild-Type and Fmr1 Knockout Mice, a Model of Fragile X Syndrome

Design and Synthesis of Arylpiperazine Serotonergic/Dopaminergic Ligands with Neuroprotective Properties

Evaluating the effect of R-Baclofen and LP-211 on autistic behavior of the BTBR and Fmr1 -KO mouse models

Behavioral, Anti-Inflammatory, and Neuroprotective Effects of a Novel FPR2 Agonist in Two Mouse Models of Autism

Low Basicity as a Characteristic for Atypical Ligands of Serotonin Receptor 5-HT2

The 5-HT7 receptor triggers cerebellar long-term synaptic depression via PKC-MAPK

5-HT1A receptor, an old target for new therapeutic agents

The Contribution of Formyl Peptide Receptor Dysfunction to the Course of Neuroinflammation: A Potential Role in the Brain Pathology

THE PROTECTIVE PROPERTIES OF NEW AGONISTS OF FPR2 ON THE EVOKED BY BACTERIAL ENDOTOXIN CHANGES: IN VITRO STUDY IN GLIAL CELLS

Mitochondrial Membranes of Human SH-SY5Y Neuroblastoma Cells Express Serotonin 5-HT7 Receptor

Activation of Serotonin 5-HT7 Receptors Modulates Hippocampal Synaptic Plasticity by Stimulation of Adenylate Cyclases and Rescues Learning and Behavior in a Mouse Model of Fragile X Syndrome

Time-Dependent Protective and Pro-Resolving Effects of FPR2 Agonists on Lipopolysaccharide-Exposed Microglia Cells Involve Inhibition of NF-κB and MAPKs Pathways

The brain-penetrant 5-HT 7 receptor agonist LP-211 reduces the sensory and affective components of neuropathic pain

LP-211 is a brain penetrant selective agonist for the serotonin 5-HT7 receptor

Microglia Depletion Attenuates the Pro-Resolving Activity of the Formyl Peptide Receptor 2 Agonist AMS21 Related to Inhibition of Inflammasome NLRP3 Signalling Pathway: A Study of Organotypic Hippocampal Cultures

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