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6‑Amino-3-methylpyrimidinones as Potent, Selective, and Orally Efficacious SHP2 Inhibitors

Journal of medicinal chemistry, 2019-02, Vol.62 (4), p.1793-1802

2019

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Optimization of Fused Bicyclic Allosteric SHP2 Inhibitors

Journal of medicinal chemistry, 2019-02, Vol.62 (4), p.1781-1792

2019

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A novel diclofenac-hydrogel conjugate system for intraarticular sustained release: Development of 2-pyridylamino-substituted 1-phenylethanol (PAPE) and its derivatives as tunable traceless linkers

International journal of pharmaceutics, 2020-07, Vol.585, p.119519-119519, Article 119519

2020

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Systematic Evaluation of Wajima Superposition (Steady-State Concentration to Mean Residence Time) in the Estimation of Human Intravenous Pharmacokinetic Profile

Journal of pharmaceutical sciences, 2016-03, Vol.105 (3), p.1277-1287

2016

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Work productivity loss in mild to moderate COPD: lessons learned from the CanCOLD study

The European respiratory journal, 2017-09, Vol.50 (3), p.1701154-1701154

2017

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Alterations in the expression of the NF-κB family member RelB as a novel marker of cardiovascular outcomes during acute exacerbations of chronic obstructive pulmonary disease

PloS one, 2014-11, Vol.9 (11), p.e112965-e112965

2014

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Correction to Optimization of Fused Bicyclic Allosteric SHP2 Inhibitors

Journal of medicinal chemistry, 2019-04, Vol.62 (7), p.3780-3780

2019

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Correction to 6‑Amino-3-methylpyrimidinones as Potent, Selective, and Orally Efficacious SHP2 Inhibitors

Journal of medicinal chemistry, 2019-04, Vol.62 (7), p.3781-3781

2019

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Undiagnosed Chronic Obstructive Pulmonary Disease Contributes to the Burden of Health Care Use. Data from the CanCOLD Study

American journal of respiratory and critical care medicine, 2016-08, Vol.194 (3), p.285-298

2016

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Linking childhood maltreatment and depressive symptoms: identity, shame, and age effects

Current psychology (New Brunswick, N.J.), 2024-04, Vol.43 (13), p.11904-11913

2024

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High-dose intravenous hydromorphone for patients who use opioids in the hospital setting: time to reduce the barriers

Harm reduction journal, 2021-08, Vol.18 (1), p.87-87, Article 87

2021

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Understanding loneliness: The roles of self- and interpersonal dysfunction and early parental indifference

Bulletin of the Menninger Clinic, 2023-09, Vol.87 (3), p.266-290

2023

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Club Cell-16 and RelB as Novel Determinants of Arterial Stiffness in Exacerbating COPD Patients

PloS one, 2016-02, Vol.11 (2), p.e0149974-e0149974

2016

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Identification of TNO155, an Allosteric SHP2 Inhibitor for the Treatment of Cancer

Journal of medicinal chemistry, 2020-11, Vol.63 (22), p.13578-13594

2020

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Total Airway Count on Computed Tomography and the Risk of Chronic Obstructive Pulmonary Disease Progression. Findings from a Population-based Study

American journal of respiratory and critical care medicine, 2018-01, Vol.197 (1), p.56-65

2018

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Increased plasma EPO and MIP-1α are associated with recruitment of vascular progenitors but not CD34(+) cells in autologous peripheral blood stem cell grafts

Experimental hematology, 2009-06, Vol.37 (6), p.673-678

2009

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Reduced hemoglobin on day of peripheral blood progenitor cell collection is associated with low graft content of vascular progenitors and increased toxicity after autologous hematopoietic stem cell transplantation

Transfusion (Philadelphia, Pa.), 2008-11, Vol.48 (11), p.2421-2428

2008

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Characteristics of COPD in never-smokers and ever-smokers in the general population: results from the CanCOLD study

Thorax, 2015-09, Vol.70 (9), p.822-829

2015

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Distinct profile of vascular progenitor attachment to extracellular matrix proteins in cancer patients

Clinical and investigative medicine, 2012-04, Vol.35 (2), p.E86-E95

2012

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Impaired Sleep Quality in COPD Is Associated With Exacerbations: The CanCOLD Cohort Study

Chest, 2019-11, Vol.156 (5), p.852-863

2019

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Impaired Spirometry and COPD Increase the Risk of Cardiovascular Disease: A Canadian Cohort Study

Chest, 2023-09, Vol.164 (3), p.637-649

2023

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Abnormal Exertional Breathlessness on Cardiopulmonary Cycle Exercise Testing in Relation to Self-Reported and Physiologic Responses in Chronic Airflow Limitation

Chest, 2024-07, Vol.166 (1), p.81-94

2024

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Impaired Spirometry and COPD Increase the Risk of Cardiovascular Disease

Chest, 2023-09, Vol.164 (3), p.637-649

2023

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Normative Reference Equations for Breathlessness Intensity during Incremental Cardiopulmonary Cycle Exercise Testing

Annals of the American Thoracic Society, 2024-01, Vol.21 (1), p.56-67

2024

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6‑Amino-3-methylpyrimidinones as Potent, Selective, and Orally Efficacious SHP2 Inhibitors

Optimization of Fused Bicyclic Allosteric SHP2 Inhibitors

A novel diclofenac-hydrogel conjugate system for intraarticular sustained release: Development of 2-pyridylamino-substituted 1-phenylethanol (PAPE) and its derivatives as tunable traceless linkers

Systematic Evaluation of Wajima Superposition (Steady-State Concentration to Mean Residence Time) in the Estimation of Human Intravenous Pharmacokinetic Profile

Work productivity loss in mild to moderate COPD: lessons learned from the CanCOLD study

Allosteric Inhibition of SHP2: Identification of a Potent, Selective, and Orally Efficacious Phosphatase Inhibitor

Alterations in the expression of the NF-κB family member RelB as a novel marker of cardiovascular outcomes during acute exacerbations of chronic obstructive pulmonary disease

Correction to Optimization of Fused Bicyclic Allosteric SHP2 Inhibitors

Correction to 6‑Amino-3-methylpyrimidinones as Potent, Selective, and Orally Efficacious SHP2 Inhibitors

Undiagnosed Chronic Obstructive Pulmonary Disease Contributes to the Burden of Health Care Use. Data from the CanCOLD Study

Linking childhood maltreatment and depressive symptoms: identity, shame, and age effects

High-dose intravenous hydromorphone for patients who use opioids in the hospital setting: time to reduce the barriers

Understanding loneliness: The roles of self- and interpersonal dysfunction and early parental indifference

Club Cell-16 and RelB as Novel Determinants of Arterial Stiffness in Exacerbating COPD Patients

Identification of TNO155, an Allosteric SHP2 Inhibitor for the Treatment of Cancer

Total Airway Count on Computed Tomography and the Risk of Chronic Obstructive Pulmonary Disease Progression. Findings from a Population-based Study

Increased plasma EPO and MIP-1α are associated with recruitment of vascular progenitors but not CD34(+) cells in autologous peripheral blood stem cell grafts

Reduced hemoglobin on day of peripheral blood progenitor cell collection is associated with low graft content of vascular progenitors and increased toxicity after autologous hematopoietic stem cell transplantation

Characteristics of COPD in never-smokers and ever-smokers in the general population: results from the CanCOLD study

Distinct profile of vascular progenitor attachment to extracellular matrix proteins in cancer patients

Impaired Sleep Quality in COPD Is Associated With Exacerbations: The CanCOLD Cohort Study

Impaired Spirometry and COPD Increase the Risk of Cardiovascular Disease: A Canadian Cohort Study

Abnormal Exertional Breathlessness on Cardiopulmonary Cycle Exercise Testing in Relation to Self-Reported and Physiologic Responses in Chronic Airflow Limitation

Impaired Spirometry and COPD Increase the Risk of Cardiovascular Disease

Normative Reference Equations for Breathlessness Intensity during Incremental Cardiopulmonary Cycle Exercise Testing

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