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Regulation and aggregation of intrinsically disordered peptides

Proceedings of the National Academy of Sciences - PNAS, 2015-03, Vol.112 (9), p.2758-2763

2015

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Effects of eribulin, vincristine, paclitaxel and ixabepilone on fast axonal transport and kinesin-1 driven microtubule gliding: Implications for chemotherapy-induced peripheral neuropathy

Neurotoxicology (Park Forest South), 2013-07, Vol.37, p.231-239

2013

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Methods in Tau Cell Biology

First edition., 2017

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Tau Assembly: The Dominant Role of PHF6 (VQIVYK) in Microtubule Binding Region Repeat R3

The journal of physical chemistry. B, 2015-04, Vol.119 (13), p.4582-4593

2015

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Microtubule and tubulin binding and regulation of microtubule dynamics by the antibody drug conjugate (ADC) payload, monomethyl auristatin E (MMAE): Mechanistic insights into MMAE ADC peripheral neuropathy

Toxicology and applied pharmacology, 2021-06, Vol.421, p.115534, Article 115534

2021

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Pathogenic forms of tau inhibit kinesin-dependent axonal transport through a mechanism involving activation of axonal phosphotransferases

The Journal of neuroscience, 2011-07, Vol.31 (27), p.9858-9868

2011

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A novel MAPT mutation, G55R, in a frontotemporal dementia patient leads to altered Tau function

PloS one, 2013-09, Vol.8 (9), p.e76409-e76409

2013

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Amyloid β‑Protein C‑Terminal Fragments: Formation of Cylindrins and β‑Barrels

Journal of the American Chemical Society, 2016-01, Vol.138 (2), p.549-557

2016

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The amino terminus of tau inhibits kinesin-dependent axonal transport: Implications for filament toxicity

Journal of neuroscience research, 2009-02, Vol.87 (2), p.440-451

2009

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Phosphorylation in the amino terminus of tau prevents inhibition of anterograde axonal transport

Neurobiology of aging, 2012-04, Vol.33 (4), p.826.e15-826.e30

2012

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Amino Acid Metaclusters: Implications of Growth Trends on Peptide Self-Assembly and Structure

Analytical chemistry (Washington), 2016-01, Vol.88 (1), p.868-876

2016

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Axonal Transport Defects in Neurodegenerative Diseases

The Journal of neuroscience, 2009-10, Vol.29 (41), p.12776-12786

2009

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βIII-tubulin enhances efficacy of cabazitaxel as compared with docetaxel

Cancer chemotherapy and pharmacology, 2017-07, Vol.80 (1), p.151-164

2017

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Tau isoform–specific stabilization of intermediate states during microtubule assembly and disassembly

The Journal of biological chemistry, 2019-08, Vol.294 (33), p.12265-12280

2019

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Oligomerization of the microtubule‐associated protein tau is mediated by its N‐terminal sequences: implications for normal and pathological tau action

Journal of neurochemistry, 2016-06, Vol.137 (6), p.939-954

2016

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Tau Aggregation Propensity Engrained in Its Solution State

The journal of physical chemistry. B, 2015-11, Vol.119 (45), p.14421-14432

2015

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Initiation of assembly of tau(273-284) and its ΔK280 mutant: an experimental and computational study

Physical chemistry chemical physics : PCCP, 2013-06, Vol.15 (23), p.8916-8928

2013

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Cinnamon extract inhibits tau aggregation associated with Alzheimer's disease in vitro

Journal of Alzheimer's disease, 2009, Vol.17 (3), p.585

2009

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1,2,3,4,6-penta-O-galloyl-β-d-glucopyranose binds to the N-terminal metal binding region to inhibit amyloid β-protein oligomer and fibril formation

International journal of mass spectrometry, 2017-09, Vol.420, p.24-34

2017

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Caspase Cleavage of Tau: Linking Amyloid and Neurofibrillary Tangles in Alzheimer's Disease

Proceedings of the National Academy of Sciences - PNAS, 2003-08, Vol.100 (17), p.10032-10037

2003

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Digital quantification of neurite outgrowth and retraction by phase-contrast microscopy: A tau perspective

Methods in cell biology, 2017, Vol.141, p.217-228

2017

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Effects of pH and Charge State on Peptide Assembly: The YVIFL Model System

The journal of physical chemistry. B, 2013-09, Vol.117 (37), p.10759-10768

2013

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Factors That Drive Peptide Assembly from Native to Amyloid Structures: Experimental and Theoretical Analysis of [Leu-5]-Enkephalin Mutants

The journal of physical chemistry. B, 2014-07, Vol.118 (26), p.7247-7256

2014

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Expression and isolation of recombinant tau

Methods in cell biology, 2017, Vol.141, p.3-26

2017

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Factors That Drive Peptide Assembly and Fibril Formation: Experimental and Theoretical Analysis of Sup35 NNQQNY Mutants

The journal of physical chemistry. B, 2013-07, Vol.117 (28), p.8436-8446

2013

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Regulation and aggregation of intrinsically disordered peptides

Effects of eribulin, vincristine, paclitaxel and ixabepilone on fast axonal transport and kinesin-1 driven microtubule gliding: Implications for chemotherapy-induced peripheral neuropathy

Methods in Tau Cell Biology

Tau Assembly: The Dominant Role of PHF6 (VQIVYK) in Microtubule Binding Region Repeat R3

Microtubule and tubulin binding and regulation of microtubule dynamics by the antibody drug conjugate (ADC) payload, monomethyl auristatin E (MMAE): Mechanistic insights into MMAE ADC peripheral neuropathy

Pathogenic forms of tau inhibit kinesin-dependent axonal transport through a mechanism involving activation of axonal phosphotransferases

A novel MAPT mutation, G55R, in a frontotemporal dementia patient leads to altered Tau function

Amyloid β‑Protein C‑Terminal Fragments: Formation of Cylindrins and β‑Barrels

The amino terminus of tau inhibits kinesin-dependent axonal transport: Implications for filament toxicity

Phosphorylation in the amino terminus of tau prevents inhibition of anterograde axonal transport

Amino Acid Metaclusters: Implications of Growth Trends on Peptide Self-Assembly and Structure

Axonal Transport Defects in Neurodegenerative Diseases

βIII-tubulin enhances efficacy of cabazitaxel as compared with docetaxel

Tau isoform–specific stabilization of intermediate states during microtubule assembly and disassembly

Oligomerization of the microtubule‐associated protein tau is mediated by its N‐terminal sequences: implications for normal and pathological tau action

Tau Aggregation Propensity Engrained in Its Solution State

Initiation of assembly of tau(273-284) and its ΔK280 mutant: an experimental and computational study

Cinnamon extract inhibits tau aggregation associated with Alzheimer's disease in vitro

1,2,3,4,6-penta-O-galloyl-β-d-glucopyranose binds to the N-terminal metal binding region to inhibit amyloid β-protein oligomer and fibril formation

Caspase Cleavage of Tau: Linking Amyloid and Neurofibrillary Tangles in Alzheimer's Disease

Digital quantification of neurite outgrowth and retraction by phase-contrast microscopy: A tau perspective

Effects of pH and Charge State on Peptide Assembly: The YVIFL Model System

Factors That Drive Peptide Assembly from Native to Amyloid Structures: Experimental and Theoretical Analysis of [Leu-5]-Enkephalin Mutants

Expression and isolation of recombinant tau

Factors That Drive Peptide Assembly and Fibril Formation: Experimental and Theoretical Analysis of Sup35 NNQQNY Mutants

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