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Genetic Analysis of 779 Advanced Differentiated and Anaplastic Thyroid Cancers

Clinical cancer research, 2018-07, Vol.24 (13), p.3059-3068

2018

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The multicellular tumor spheroid model for high-throughput cancer drug discovery

Expert opinion on drug discovery, 2012-09, Vol.7 (9), p.819-830

2012

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Larrea tridentata: A novel source for anti-parasitic agents active against Entamoeba histolytica, Giardia lamblia and Naegleria fowleri

PLoS neglected tropical diseases, 2017-08, Vol.11 (8), p.e0005832-e0005832

2017

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The validation of new CHD1L inhibitors as a therapeutic strategy for cancer

Biomedicine & pharmacotherapy, 2024-01, Vol.170, p.116037-116037, Article 116037

2024

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CHD1L Regulates Cell Survival in Breast Cancer and Its Inhibition by OTI-611 Impedes the DNA Damage Response and Induces PARthanatos

International journal of molecular sciences, 2024-08, Vol.25 (16), p.8590

2024

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AST-487 Inhibits RET Kinase Driven TERT Expression in Bladder Cancer

International journal of molecular sciences, 2022-09, Vol.23 (18), p.10819

2022

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The isolation and characterization of β-glucogallin as a novel aldose reductase inhibitor from Emblica officinalis

PloS one, 2012-04, Vol.7 (4), p.e31399-e31399

2012

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High-Content Drug Discovery Targeting Molecular Bladder Cancer Subtypes

International journal of molecular sciences, 2022-09, Vol.23 (18), p.10605

2022

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Aldose reductase inhibition alleviates hyperglycemic effects on human retinal pigment epithelial cells

Chemico-biological interactions, 2015-06, Vol.234, p.254-260

2015

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Characterization of Emodin as a Therapeutic Agent for Diabetic Cataract

Journal of natural products (Washington, D.C.), 2016-05, Vol.79 (5), p.1439-1444

2016

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Inhibition of α-glucosidase, α-amylase, and aldose reductase by potato polyphenolic compounds

PloS one, 2018, Vol.13 (1), p.e0191025-e0191025

2018

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Response of Osteosarcoma Cell Lines to a Novel CHD1L Inhibitor

The FASEB journal, 2022-05, Vol.36 (S1), p.n/a

2022

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Identification of small molecule inhibitors of the Chikungunya virus nsP1 RNA capping enzyme

Antiviral research, 2018-06, Vol.154, p.124-131

2018

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High-throughput imaging: Focusing in on drug discovery in 3D

Methods (San Diego, Calif.), 2016-03, Vol.96, p.97-102

2016

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An improved high yield total synthesis and cytotoxicity study of the marine alkaloid neoamphimedine: an ATP-competitive inhibitor of topoisomerase IIα and potent anticancer agent

Marine drugs, 2014-09, Vol.12 (9), p.4833-4850

2014

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Isolating and targeting the real-time plasticity and malignant properties of epithelial-mesenchymal transition in cancer

Oncogene, 2021-04, Vol.40 (16), p.2884-2897

2021

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TRIM28 is a transcriptional activator of the mutant TERT promoter in human bladder cancer

Proceedings of the National Academy of Sciences - PNAS, 2021-09, Vol.118 (38)

2021

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Design, Synthesis, and Biological Evaluation of the First Inhibitors of Oncogenic CHD1L

Journal of medicinal chemistry, 2022-03, Vol.65 (5), p.3943-3961

2022

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3D models of epithelial-mesenchymal transition in breast cancer metastasis: high-throughput screening assay development, validation, and pilot screen

Journal of biomolecular screening, 2011-02, Vol.16 (2), p.141-154

2011

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First-in-Class Inhibitors of Oncogenic CHD1L with Preclinical Activity against Colorectal Cancer

Molecular cancer therapeutics, 2020-08, Vol.19 (8), p.1598-1612

2020

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Oxidative stress as a candidate mechanism for accelerated neuroectodermal differentiation due to trisomy 21

Free radical biology & medicine, 2022-06, Vol.186, p.32-42

2022

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A high-content assay to identify small-molecule modulators of a cancer stem cell population in luminal breast cancer

Journal of biomolecular screening, 2012-10, Vol.17 (9), p.1211-1220

2012

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Targeting HIV-1 Protease Autoprocessing for High-throughput Drug Discovery and Drug Resistance Assessment

Scientific reports, 2019-01, Vol.9 (1), p.301-301, Article 301

2019

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Advanced High-Content-Screening Applications of Clonogenicity in Cancer

SLAS discovery, 2020-08, Vol.25 (7), p.734-743

2020

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High Throughput Screen Identifies the DNMT1 (DNA Methyltransferase-1) Inhibitor, 5-Azacytidine, as a Potent Inducer of PTEN (Phosphatase and Tensin Homolog): Central Role for PTEN in 5-Azacytidine Protection Against Pathological Vascular Remodeling

Arteriosclerosis, thrombosis, and vascular biology, 2020-08, Vol.40 (8), p.1854-1869

2020

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Genetic Analysis of 779 Advanced Differentiated and Anaplastic Thyroid Cancers

The multicellular tumor spheroid model for high-throughput cancer drug discovery

Larrea tridentata: A novel source for anti-parasitic agents active against Entamoeba histolytica, Giardia lamblia and Naegleria fowleri

The validation of new CHD1L inhibitors as a therapeutic strategy for cancer

CHD1L Regulates Cell Survival in Breast Cancer and Its Inhibition by OTI-611 Impedes the DNA Damage Response and Induces PARthanatos

AST-487 Inhibits RET Kinase Driven TERT Expression in Bladder Cancer

The isolation and characterization of β-glucogallin as a novel aldose reductase inhibitor from Emblica officinalis

High-Content Drug Discovery Targeting Molecular Bladder Cancer Subtypes

Aldose reductase inhibition alleviates hyperglycemic effects on human retinal pigment epithelial cells

Characterization of Emodin as a Therapeutic Agent for Diabetic Cataract

Inhibition of α-glucosidase, α-amylase, and aldose reductase by potato polyphenolic compounds

Response of Osteosarcoma Cell Lines to a Novel CHD1L Inhibitor

Identification of small molecule inhibitors of the Chikungunya virus nsP1 RNA capping enzyme

High-throughput imaging: Focusing in on drug discovery in 3D

An improved high yield total synthesis and cytotoxicity study of the marine alkaloid neoamphimedine: an ATP-competitive inhibitor of topoisomerase IIα and potent anticancer agent

Isolating and targeting the real-time plasticity and malignant properties of epithelial-mesenchymal transition in cancer

TRIM28 is a transcriptional activator of the mutant TERT promoter in human bladder cancer

Design, Synthesis, and Biological Evaluation of the First Inhibitors of Oncogenic CHD1L

3D models of epithelial-mesenchymal transition in breast cancer metastasis: high-throughput screening assay development, validation, and pilot screen

First-in-Class Inhibitors of Oncogenic CHD1L with Preclinical Activity against Colorectal Cancer

Oxidative stress as a candidate mechanism for accelerated neuroectodermal differentiation due to trisomy 21

A high-content assay to identify small-molecule modulators of a cancer stem cell population in luminal breast cancer

Targeting HIV-1 Protease Autoprocessing for High-throughput Drug Discovery and Drug Resistance Assessment

Advanced High-Content-Screening Applications of Clonogenicity in Cancer

High Throughput Screen Identifies the DNMT1 (DNA Methyltransferase-1) Inhibitor, 5-Azacytidine, as a Potent Inducer of PTEN (Phosphatase and Tensin Homolog): Central Role for PTEN in 5-Azacytidine Protection Against Pathological Vascular Remodeling

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