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Oxysterols: Old Tale, New Twists

Annual review of pharmacology and toxicology, 2016-01, Vol.56 (1), p.447-467

2016

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The terminal enzymes of cholesterol synthesis, DHCR24 and DHCR7, interact physically and functionally[S]

Journal of lipid research, 2015-04, Vol.56 (4), p.888-897

2015

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Cholesterol increases protein levels of the E3 ligase MARCH6 and thereby stimulates protein degradation

The Journal of biological chemistry, 2019-02, Vol.294 (7), p.2436-2448

2019

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Cholesterol synthesis enzyme SC4MOL is fine-tuned by sterols and targeted for degradation by the E3 ligase MARCHF6

Journal of lipid research, 2023-05, Vol.64 (5), p.100362-100362, Article 100362

2023

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Squalene mono-oxygenase, a key enzyme in cholesterol synthesis, is stabilized by unsaturated fatty acids

Biochemical journal, 2014-08, Vol.461 (3), p.435-442

2014

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Akt acutely activates the cholesterogenic transcription factor SREBP-2

Biochimica et biophysica acta, 2012-02, Vol.1823 (2), p.458-464

2012

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Signaling regulates activity of DHCR24, the final enzyme in cholesterol synthesis[S]

Journal of lipid research, 2014-03, Vol.55 (3), p.410-420

2014

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Cholesterol-mediated Degradation of 7-Dehydrocholesterol Reductase Switches the Balance from Cholesterol to Vitamin D Synthesis

The Journal of biological chemistry, 2016-04, Vol.291 (16), p.8363-8373

2016

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Navigating the Shallows and Rapids of Cholesterol Synthesis Downstream of HMGCR

Journal of Nutritional Science and Vitaminology, 2015, Vol.61(Supplement), pp.S154-S156

2015

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DHCR7: A vital enzyme switch between cholesterol and vitamin D production

Progress in lipid research, 2016-10, Vol.64, p.138-151

2016

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The Akt–SREBP nexus: cell signaling meets lipid metabolism

Trends in endocrinology and metabolism, 2010-05, Vol.21 (5), p.268-276

2010

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The cholesterol synthesis enzyme lanosterol 14α-demethylase is post-translationally regulated by the E3 ubiquitin ligase MARCH6

Biochemical journal, 2020-01, Vol.477 (2), p.541-555

2020

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The Cholesterol Synthesis Enzyme Lanosterol 14α‐Demethylase is Post‐Translationally Regulated by the E3 Ubiquitin Ligase MARCH6

The FASEB journal, 2020-04, Vol.34 (S1), p.1-1

2020

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Phosphorylation regulates activity of 7-dehydrocholesterol reductase (DHCR7), a terminal enzyme of cholesterol synthesis

The Journal of steroid biochemistry and molecular biology, 2017-01, Vol.165 (Pt B), p.363-368

2017

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The blood vasculature instructs lymphatic patterning in a SOX7‐dependent manner

The EMBO journal, 2023-03, Vol.42 (5), p.e109032-n/a

2023

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A dominant-negative SOX18 mutant disrupts multiple regulatory layers essential to transcription factor activity

Nucleic acids research, 2021-11, Vol.49 (19), p.10931-10955

2021

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Manipulating Cholesterol Status Within Cells

Methods in molecular biology (Clifton, N.J.), 2017-01, Vol.1583, p.41

2017

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The Interplay between Cholesterol and Vitamin D Biosynthesis

The FASEB journal, 2015-04, Vol.29 (S1)

2015

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Signaling Regulates Activity of DHCR24, the Final Enzyme in Cholesterol Synthesis

The FASEB journal, 2015-04, Vol.29 (S1)

2015

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The role of signalling in cellular cholesterol homeostasis

IUBMB life, 2013-08, Vol.65 (8), p.675-684

2013

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Akt Phosphorylates Sec24: New Clues into the Regulation of ER‐to‐Golgi Trafficking

Traffic (Copenhagen, Denmark), 2011-01, Vol.12 (1), p.19-27

2011

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Measuring Activity of Cholesterol Synthesis Enzymes Using Gas Chromatography/Mass Spectrometry

Methods in molecular biology (Clifton, N.J.), 2017-01, Vol.1583, p.211

2017

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Cholesterol‐Mediated Degradation of 7‐Dehydrocholesterol Reductase Switches the Balance from Cholesterol to Vitamin D Synthesis

The FASEB journal, 2016-04, Vol.30 (S1)

2016

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Signalling and cholesterol metabolism

The FASEB journal, 2013-04, Vol.27 (S1)

2013

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Cholesterol through the looking glass: ability of its enantiomer also to elicit homeostatic responses

The Journal of biological chemistry, 2012-09, Vol.287 (40), p.33897-33904

2012

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Biochemistry & Molecular Biology
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Cho Cells
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Cholesterol
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Cholesterol - Metabolism
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Cricetinae
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Cricetulus
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Cell Biology
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Oxidoreductases Acting On Ch-Ch Group Donors - Metabolism
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Lipids
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Phosphorylation
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Mice
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Oxidoreductases Acting On Ch-Ch Group Donors - Genetics
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7-Dehydrocholesterol
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Cholesterol - Biosynthesis
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Gene Expression Regulation
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Nerve Tissue Proteins - Metabolism
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Oxysterols: Old Tale, New Twists

The terminal enzymes of cholesterol synthesis, DHCR24 and DHCR7, interact physically and functionally[S]

Cholesterol increases protein levels of the E3 ligase MARCH6 and thereby stimulates protein degradation

Cholesterol synthesis enzyme SC4MOL is fine-tuned by sterols and targeted for degradation by the E3 ligase MARCHF6

Squalene mono-oxygenase, a key enzyme in cholesterol synthesis, is stabilized by unsaturated fatty acids

Akt acutely activates the cholesterogenic transcription factor SREBP-2

Signaling regulates activity of DHCR24, the final enzyme in cholesterol synthesis[S]

Cholesterol-mediated Degradation of 7-Dehydrocholesterol Reductase Switches the Balance from Cholesterol to Vitamin D Synthesis

Navigating the Shallows and Rapids of Cholesterol Synthesis Downstream of HMGCR

DHCR7: A vital enzyme switch between cholesterol and vitamin D production

The Akt–SREBP nexus: cell signaling meets lipid metabolism

The cholesterol synthesis enzyme lanosterol 14α-demethylase is post-translationally regulated by the E3 ubiquitin ligase MARCH6

The Cholesterol Synthesis Enzyme Lanosterol 14α‐Demethylase is Post‐Translationally Regulated by the E3 Ubiquitin Ligase MARCH6

Phosphorylation regulates activity of 7-dehydrocholesterol reductase (DHCR7), a terminal enzyme of cholesterol synthesis

The blood vasculature instructs lymphatic patterning in a SOX7‐dependent manner

A dominant-negative SOX18 mutant disrupts multiple regulatory layers essential to transcription factor activity

Manipulating Cholesterol Status Within Cells

The Interplay between Cholesterol and Vitamin D Biosynthesis

Signaling Regulates Activity of DHCR24, the Final Enzyme in Cholesterol Synthesis

The role of signalling in cellular cholesterol homeostasis

Akt Phosphorylates Sec24: New Clues into the Regulation of ER‐to‐Golgi Trafficking

Measuring Activity of Cholesterol Synthesis Enzymes Using Gas Chromatography/Mass Spectrometry

Cholesterol‐Mediated Degradation of 7‐Dehydrocholesterol Reductase Switches the Balance from Cholesterol to Vitamin D Synthesis

Signalling and cholesterol metabolism

Cholesterol through the looking glass: ability of its enantiomer also to elicit homeostatic responses

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