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Occurrence of Emodin, Chrysophanol and Physcion in Vegetables, Herbs and Liquors. Genotoxicity and Anti-genotoxicity of the Anthraquinones and of the Whole Plants

Food and chemical toxicology, 1999-05, Vol.37 (5), p.481-491

1999

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Decreased tumor surveillance in perforin-deficient mice

The Journal of experimental medicine, 1996-11, Vol.184 (5), p.1781-1790

1996

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Oxidative stress related DNA adducts in the liver of female rats fed with sunflower-, rapeseed-, olive- or coconut oil supplemented diets

Chemico-biological interactions, 2006-02, Vol.159 (2), p.81-89

2006

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Correlation of DNA adduct levels with tumor incidence: carcinogenic potency of DNA adducts

Mutation research, 1999-03, Vol.424 (1), p.237-247

1999

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Nonmonotonic Dose-Response Relationships: Mechanistic Basis, Kinetic Modeling, and Implications for Risk Assessment

Toxicological sciences, 2004-01, Vol.77 (1), p.151-157

2004

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A true threshold dose in chemical carcinogenesis cannot be defined for a population, irrespective of the mode of action

Human & experimental toxicology, 2000-10, Vol.19 (10), p.566-568

Lutz, W K

2000

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Discrimination between genotoxicity and cytotoxicity in the induction of DNA double-strand breaks in cells treated with etoposide, melphalan, cisplatin, potassium cyanide, Triton X-100, and γ-irradiation

Mutation research, 1998-02, Vol.413 (1), p.83-94

1998

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On the Role of DNA Double-Strand Breaks in Toxicity and Carcinogenesis

Critical reviews in toxicology, 1997-01, Vol.27 (2), p.155-174

1997

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Dose-response relationships in chemical carcinogenesis reflect differences in individual susceptibility. Consequences for cancer risk assessment, extrapolation, and prevention

Human & experimental toxicology, 1999-12, Vol.18 (12), p.707-712

Lutz, W K

1999

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The carcinogenic potential of ethyl carbamate (urethane): Risk assessment at human dietary exposure levels

Food and Chemical Toxicology, 1990-03, Vol.28 (3), p.205-211

1990

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Metabolic Profiling of Glucuronides in Human Urine by LC−MS/MS and Partial Least-Squares Discriminant Analysis for Classification and Prediction of Gender

Analytical chemistry (Washington), 2006-07, Vol.78 (13), p.4564-4571

2006

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Dose : response relationship and low dose extrapolation in chemical carcinogenesis

Carcinogenesis (New York), 1990-08, Vol.11 (8), p.1243-1247

LUTZ, W. K

1990

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Chemical carcinogens and overnutrition in diet-related cancer

Carcinogenesis (New York), 1992-12, Vol.13 (12), p.2211-2216

1992

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Chemoimmunotherapy for melanoma with dacarbazine and 2,4-dinitrochlorobenzene elicits a specific T cell-dependent immune response

Cancer Immunology, Immunotherapy, 2002-10, Vol.51 (8), p.431-439

2002

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Nonlinearity and thresholds in dose–response relationships for carcinogenicity due to sampling variation, logarithmic dose scaling, or small differences in individual susceptibility

Toxicology and applied pharmacology, 2005-09, Vol.207 (2), p.565-569

2005

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Discrimination between genotoxicity and cytotoxicity for the induction of DNA double-strand breaks in cells treated with aldehydes and diepoxides

Mutation research, 1999-04, Vol.441 (1), p.85-93

1999

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Factors affecting the genotoxic potency ranking of natural anthraquinones in mammalian cell culture systems

Mutation research, 1998-05, Vol.414 (1), p.125-129

1998

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Statistical model to estimate a threshold dose and its confidence limits for the analysis of sublinear dose–response relationships, exemplified for mutagenicity data

Mutation research, 2009-08, Vol.678 (2), p.118-122

2009

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Linear dose-response relationship for DNA adducts in rat liver from chronic exposure to aflatoxin B1

Carcinogenesis (New York), 1990-12, Vol.11 (12), p.2133-2135

1990

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Investigation of the Induction of DNA Double-Strand Breaks by Methylenediphenyl-4,4′-diisocyanate in Cultured Human Lung Epithelial Cells

Toxicological sciences, 1998-11, Vol.46 (1), p.83-89

1998

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Time-dependent effects of sodium arsenite on DNA breakage and apoptosis observed in the comet assay

Mutation research, 2006-02, Vol.603 (2), p.121-128

2006

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Investigation of the covalent binding of styrene-7,8-oxide to DNA in rat and mouse

Carcinogenesis (New York), 1992-02, Vol.13 (2), p.193-197

1992

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Correlation of Individual Papilloma Latency Time with DNA Adducts, 8-Hydroxy-2'-Deoxyguanosine, and the Rate of DNA Synthesis in the Epidermis of Mice Treated with 7,12-Dimethylbenz[a]Anthracene

Proceedings of the National Academy of Sciences - PNAS, 1995-06, Vol.92 (13), p.5900-5904

1995

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Assessment of the risk of formation of carcinogenic N-nitroso compounds from dietary precursors in the stomach

Food and Chemical Toxicology, 1987, Vol.25 (1), p.91-108

1987

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Chemoimmunotherapy for melanoma with dacarbazine and 2,4-dinitrochlorobenzene: results from a murine tumour model

Melanoma research, 2001-06, Vol.11 (3), p.247-253

2001

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Occurrence of Emodin, Chrysophanol and Physcion in Vegetables, Herbs and Liquors. Genotoxicity and Anti-genotoxicity of the Anthraquinones and of the Whole Plants

Decreased tumor surveillance in perforin-deficient mice

Oxidative stress related DNA adducts in the liver of female rats fed with sunflower-, rapeseed-, olive- or coconut oil supplemented diets

Correlation of DNA adduct levels with tumor incidence: carcinogenic potency of DNA adducts

Nonmonotonic Dose-Response Relationships: Mechanistic Basis, Kinetic Modeling, and Implications for Risk Assessment

A true threshold dose in chemical carcinogenesis cannot be defined for a population, irrespective of the mode of action

Discrimination between genotoxicity and cytotoxicity in the induction of DNA double-strand breaks in cells treated with etoposide, melphalan, cisplatin, potassium cyanide, Triton X-100, and γ-irradiation

On the Role of DNA Double-Strand Breaks in Toxicity and Carcinogenesis

Dose-response relationships in chemical carcinogenesis reflect differences in individual susceptibility. Consequences for cancer risk assessment, extrapolation, and prevention

The carcinogenic potential of ethyl carbamate (urethane): Risk assessment at human dietary exposure levels

Metabolic Profiling of Glucuronides in Human Urine by LC−MS/MS and Partial Least-Squares Discriminant Analysis for Classification and Prediction of Gender

Dose : response relationship and low dose extrapolation in chemical carcinogenesis

Chemical carcinogens and overnutrition in diet-related cancer

Chemoimmunotherapy for melanoma with dacarbazine and 2,4-dinitrochlorobenzene elicits a specific T cell-dependent immune response

Nonlinearity and thresholds in dose–response relationships for carcinogenicity due to sampling variation, logarithmic dose scaling, or small differences in individual susceptibility

Discrimination between genotoxicity and cytotoxicity for the induction of DNA double-strand breaks in cells treated with aldehydes and diepoxides

Factors affecting the genotoxic potency ranking of natural anthraquinones in mammalian cell culture systems

Statistical model to estimate a threshold dose and its confidence limits for the analysis of sublinear dose–response relationships, exemplified for mutagenicity data

Linear dose-response relationship for DNA adducts in rat liver from chronic exposure to aflatoxin B1

Investigation of the Induction of DNA Double-Strand Breaks by Methylenediphenyl-4,4′-diisocyanate in Cultured Human Lung Epithelial Cells

Time-dependent effects of sodium arsenite on DNA breakage and apoptosis observed in the comet assay

Investigation of the covalent binding of styrene-7,8-oxide to DNA in rat and mouse

Correlation of Individual Papilloma Latency Time with DNA Adducts, 8-Hydroxy-2'-Deoxyguanosine, and the Rate of DNA Synthesis in the Epidermis of Mice Treated with 7,12-Dimethylbenz[a]Anthracene

Assessment of the risk of formation of carcinogenic N-nitroso compounds from dietary precursors in the stomach

Chemoimmunotherapy for melanoma with dacarbazine and 2,4-dinitrochlorobenzene: results from a murine tumour model

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