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The Synthesis of a Prodrug of Doxorubicin Designed to Provide Reduced Systemic Toxicity and Greater Target Efficacy

Journal of medicinal chemistry, 2001-11, Vol.44 (24), p.4216-4224

2001

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Chemical Synthesis of Echistatin, a Potent Inhibitor of Platelet Aggregation from Echis carinatus: Synthesis and Biological Activity of Selected Analogs

Proceedings of the National Academy of Sciences - PNAS, 1989-06, Vol.86 (11), p.4022-4026

1989

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HIV-1 protease specificity of peptide cleavage is sufficient for processing of gag and pol polyproteins

Biochemical and biophysical research communications, 1988-10, Vol.156 (1), p.297-303

1988

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Proton NMR assignments and secondary structure of the snake venom protein echistatin

Biochemistry (Easton), 1991-12, Vol.30 (50), p.11625-11636

1991

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Specific N-methylations of HPV-16 E7 peptides alter binding to the retinoblastoma suppressor protein

The Journal of biological chemistry, 1992-01, Vol.267 (2), p.908-912

1992

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Prominent depressor response to endothelin in spontaneously hypertensive rats

European journal of pharmacology, 1989-04, Vol.163 (1), p.199-203

1989

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1,4-Oxazines via intramolecular ring closure of .beta.-hydroxydiazoacetamides: phenylalanine to tetrahydroindeno[1,2-b]-1,4-oxazin-3(2H)-ones

Journal of organic chemistry, 1983-08, Vol.48 (16), p.2675-2679

1983

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Site-directed analysis of the functional domains in the factor Xa inhibitor tick anticoagulant peptide: identification of two distinct regions that constitute the enzyme recognition sites

Biochemistry (Easton), 1992-12, Vol.31 (48), p.12126-12131

1992

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An approach to peripheral vasodilator-.beta.-adrenergic blocking agents

Journal of medicinal chemistry, 1977-08, Vol.20 (8), p.1024-1029

1977

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Organolithium addition to aldehyde dimethylhydrazones: a highly diastereocontrolled synthesis of threo 2-amino alcohols, and (1R,2R)-(-)-norpseudoephedrine

Journal of the American Chemical Society, 1986-12, Vol.108 (26), p.8265-8266

1986

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2-Pyridylimidazoles as inhibitors of xanthine oxidase

Journal of medicinal chemistry, 1977-09, Vol.20 (9), p.1189-1193

1977

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Preparative methods for ergoline synthons: Uhle's ketone and the C-homo analog

Journal of organic chemistry, 1980-10, Vol.45 (21), p.4236-4238

1980

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Design and Synthesis of a Pro-Drug of Vinblastine Targeted at Treatment of Prostate Cancer with Enhanced Efficacy and Reduced Systemic Toxicity

Journal of medicinal chemistry, 2002-10, Vol.45 (21), p.4706-4715

2002

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Diethyl 3,6-dihydro-2,4-dimethyl-2,6-methano-1,3-benzothiazocine-5,11-dicarboxylates as calcium entry antagonists: new conformationally restrained analogs of Hantzsch 1,4-dihydropyridines related to nitrendipine as probes for receptor-site conformation

Journal of medicinal chemistry, 1987-04, Vol.30 (4), p.690-695

1987

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Prevention of canine coronary artery thrombosis with echistatin, a potent inhibitor of platelet aggregation from the venom of the viper, Echis carinatus

Thrombosis and haemostasis, 1990-12, Vol.64 (4), p.576

1990

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Synthesis of 4-substituted 2H-naphth[1,2-b]-1,4-oxazines, a new class of dopamine agonists

Journal of medicinal chemistry, 1984-12, Vol.27 (12), p.1607-1613

1984

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Novel Rigid Calcium-Entry Blockers: Intramolecular Reactions of 1,4-Dihydropyridine Derivatives

Synthesis (Stuttgart), 1986, Vol.1986 (2), p.144-147

1986

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Synthesis of (7R)-7H-indolo[3,4-gh][1,4]benzoxazines, a new class of D-heteroergolines with dopamine agonist activity

Journal of medicinal chemistry, 1983-03, Vol.26 (3), p.363-367

1983

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Chlorosulfonation of 2-arylimidazoles

Journal of heterocyclic chemistry, 1977-08, Vol.14 (5), p.889-892

1977

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ChemInform Abstract: Organolithium Addition to Aldehyde Dimethylhydrazones: A Highly Diastereocontrolled Synthesis of Threo 2‐Amino Alcohols and (1R,2R)‐(‐)‐Norpseudoephedrine

ChemInform, 1987-05, Vol.18 (20), p.no-no

1987

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ChemInform Abstract: Novel Rigid Calcium‐Entry Blockers: Intramolecular Reactions of 1,4‐Dihydropyridine Derivatives

Chemischer Informationsdienst, 1986-06, Vol.17 (25)

1986

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ChemInform Abstract: An Approach to Peripheral Vasodilator‐β‐adrenergic Blocking Agents

Chemischer Informationsdienst, 1977-12, Vol.8 (49)

1977

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ChemInform Abstract: 1,4‐OXAZINES VIA INTRAMOLECULAR RING CLOSURE OF β‐HYDROXYDIAZOACETAMIDES: PHENYLALANINE TO TETRAHYDROINDENO(1,2‐B)‐1,4‐OXAZIN‐3(2H)‐ONES

Chemischer Informationsdienst, 1984-01, Vol.15 (1)

1984

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ChemInform Abstract: PREPARATIVE METHODS FOR ERGOLINE SYNTHONS: UHLE′S KETONE AND THE C‐HOMO ANALOG

Chemischer Informationsdienst, 1981-02, Vol.12 (6)

1981

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ChemInform Abstract: CHLOROSULFONATION OF 2‐ARYLIMIDAZOLES

Chemischer Informationsdienst, 1978-05, Vol.9 (18)

1978

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The Synthesis of a Prodrug of Doxorubicin Designed to Provide Reduced Systemic Toxicity and Greater Target Efficacy

Chemical Synthesis of Echistatin, a Potent Inhibitor of Platelet Aggregation from Echis carinatus: Synthesis and Biological Activity of Selected Analogs

HIV-1 protease specificity of peptide cleavage is sufficient for processing of gag and pol polyproteins

Proton NMR assignments and secondary structure of the snake venom protein echistatin

Specific N-methylations of HPV-16 E7 peptides alter binding to the retinoblastoma suppressor protein

Prominent depressor response to endothelin in spontaneously hypertensive rats

1,4-Oxazines via intramolecular ring closure of .beta.-hydroxydiazoacetamides: phenylalanine to tetrahydroindeno[1,2-b]-1,4-oxazin-3(2H)-ones

Site-directed analysis of the functional domains in the factor Xa inhibitor tick anticoagulant peptide: identification of two distinct regions that constitute the enzyme recognition sites

An approach to peripheral vasodilator-.beta.-adrenergic blocking agents

Organolithium addition to aldehyde dimethylhydrazones: a highly diastereocontrolled synthesis of threo 2-amino alcohols, and (1R,2R)-(-)-norpseudoephedrine

2-Pyridylimidazoles as inhibitors of xanthine oxidase

Preparative methods for ergoline synthons: Uhle's ketone and the C-homo analog

Design and Synthesis of a Pro-Drug of Vinblastine Targeted at Treatment of Prostate Cancer with Enhanced Efficacy and Reduced Systemic Toxicity

Diethyl 3,6-dihydro-2,4-dimethyl-2,6-methano-1,3-benzothiazocine-5,11-dicarboxylates as calcium entry antagonists: new conformationally restrained analogs of Hantzsch 1,4-dihydropyridines related to nitrendipine as probes for receptor-site conformation

Prevention of canine coronary artery thrombosis with echistatin, a potent inhibitor of platelet aggregation from the venom of the viper, Echis carinatus

Synthesis of 4-substituted 2H-naphth[1,2-b]-1,4-oxazines, a new class of dopamine agonists

Novel Rigid Calcium-Entry Blockers: Intramolecular Reactions of 1,4-Dihydropyridine Derivatives

Synthesis of (7R)-7H-indolo[3,4-gh][1,4]benzoxazines, a new class of D-heteroergolines with dopamine agonist activity

Chlorosulfonation of 2-arylimidazoles

ChemInform Abstract: Organolithium Addition to Aldehyde Dimethylhydrazones: A Highly Diastereocontrolled Synthesis of Threo 2‐Amino Alcohols and (1R,2R)‐(‐)‐Norpseudoephedrine

ChemInform Abstract: Novel Rigid Calcium‐Entry Blockers: Intramolecular Reactions of 1,4‐Dihydropyridine Derivatives

ChemInform Abstract: An Approach to Peripheral Vasodilator‐β‐adrenergic Blocking Agents

ChemInform Abstract: 1,4‐OXAZINES VIA INTRAMOLECULAR RING CLOSURE OF β‐HYDROXYDIAZOACETAMIDES: PHENYLALANINE TO TETRAHYDROINDENO(1,2‐B)‐1,4‐OXAZIN‐3(2H)‐ONES

ChemInform Abstract: PREPARATIVE METHODS FOR ERGOLINE SYNTHONS: UHLE′S KETONE AND THE C‐HOMO ANALOG

ChemInform Abstract: CHLOROSULFONATION OF 2‐ARYLIMIDAZOLES

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