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Spliceosomal UsnRNP biogenesis, structure and function

Current Opinion in Cell Biology, 2001-06, Vol.13 (3), p.290-301

2001

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Essential Role for the Tudor Domain of SMN in Spliceosomal U snRNP Assembly: Implications for Spinal Muscular Atrophy

Human molecular genetics, 1999-12, Vol.8 (13), p.2351-2357

1999

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Symmetrical dimethylation of arginine residues in spliceosomal Sm protein B/B′ and the Sm-like protein LSm4, and their interaction with the SMN protein

RNA (Cambridge), 2001-11, Vol.7 (11), p.1531-1542, Article S135583820101442X

2001

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Crystal Structure of the Spliceosomal 15.5kD Protein Bound to a U4 snRNA Fragment

Molecular cell, 2000-12, Vol.6 (6), p.1331-1342

2000

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A doughnut-shaped heteromer of human Sm-like proteins binds to the 3′-end of U6 snRNA, thereby facilitating U4/U6 duplex formation in vitro

The EMBO journal, 1999-10, Vol.18 (20), p.5789-5802

1999

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The Sm Domain Is an Ancient RNA-Binding Motif with Oligo(U) Specificity

Proceedings of the National Academy of Sciences - PNAS, 2001-03, Vol.98 (7), p.3685-3689

2001

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Spliceosome structure and function

Cold Spring Harbor perspectives in biology, 2011-07, Vol.3 (7), p.a003707-a003707

2011

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The C-terminal RG Dipeptide Repeats of the Spliceosomal Sm Proteins D1 and D3 Contain Symmetrical Dimethylarginines, Which Form a Major B-cell Epitope for Anti-Sm Autoantibodies

The Journal of biological chemistry, 2000-06, Vol.275 (22), p.17122-17129

2000

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Crystal Structures of Two Sm Protein Complexes and Their Implications for the Assembly of the Spliceosomal snRNPs

Cell, 1999-02, Vol.96 (3), p.375-387

1999

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Mex67p, a novel factor for nuclear mRNA export, binds to both poly(A)+ RNA and nuclear pores

The EMBO journal, 1997-06, Vol.16 (11), p.3256-3271

1997

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The snRNP core assembly pathway: identification of stable core protein heteromeric complexes and an snRNP subcore particle in vitro

The EMBO journal, 1996-05, Vol.15 (9), p.2256-2269

1996

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The Spliceosome: Design Principles of a Dynamic RNP Machine

Cell, 2009-02, Vol.136 (4), p.701-718

2009

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Sm protein-Sm site RNA interactions within the inner ring of the spliceosomal snRNP core structure

The EMBO journal, 2001-01, Vol.20 (1-2), p.187-196

2001

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Protein functions in pre-mRNA splicing

Current opinion in cell biology, 1997-06, Vol.9 (3), p.320-328

1997

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Functional interaction of a novel 15.5kD [U4/U6.U5] tri-snRNP protein with the 5' stem-loop of U4 snRNA

The EMBO journal, 1999-11, Vol.18 (21), p.6119-6133

1999

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Identification of Both Shared and Distinct Proteins in the Major and Minor Spliceosomes

Science (American Association for the Advancement of Science), 1999-06, Vol.284 (5422), p.2003-2005

1999

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High Intranuclear Mobility and Dynamic Clustering of the Splicing Factor U1 snRNP Observed by Single Particle Tracking

Proceedings of the National Academy of Sciences - PNAS, 2001-10, Vol.98 (21), p.12021-12026

2001

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Cbf5p, a potential pseudouridine synthase, and Nhp2p, a putative RNA-binding protein, are present together with Gar1p in all H BOX/ACA-motif snoRNPs and constitute a common bipartite structure

RNA (Cambridge), 1998-12, Vol.4 (12), p.1549-1568, Article S1355838298980761

1998

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Identification by mass spectrometry and functional analysis of novel proteins of the yeast [U4/U6.U5] tri-snRNP

The EMBO journal, 1999-08, Vol.18 (16), p.4535-4548

1999

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Spliceosomal U snRNP Core Assembly: Sm Proteins Assemble onto an Sm Site RNA Nonanucleotide in a Specific and Thermodynamically Stable Manner

Molecular and Cellular Biology, 1999-10, Vol.19 (10), p.6554-6565

1999

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An evolutionarily conserved U5 snRNP-specific protein is a GTP-binding factor closely related to the ribosomal translocase EF-2

The EMBO journal, 1997-07, Vol.16 (13), p.4092-4106

1997

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Single-Stranded Antisense siRNAs Guide Target RNA Cleavage in RNAi

Cell, 2002-09, Vol.110 (5), p.563-574

2002

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Identification of the proteins of the yeast U1 small nuclear ribonucleoprotein complex by mass spectrometry

Proceedings of the National Academy of Sciences - PNAS, 1997-01, Vol.94 (2), p.385-390

1997

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A general approach for identification of RNA-protein cross-linking sites within native human spliceosomal small nuclear ribonucleoproteins (snRNPs). Analysis of RNA-protein contacts in native U1 and U4/U6.U5 snRNPs

The Journal of biological chemistry, 2000-12, Vol.275 (52), p.41458-41468

2000

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An essential signaling role for the m3G cap in the transport of U1 snRNP to the nucleus

Science (American Association for the Advancement of Science), 1990-08, Vol.249 (4970), p.786-790

1990

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Spliceosomal UsnRNP biogenesis, structure and function

Essential Role for the Tudor Domain of SMN in Spliceosomal U snRNP Assembly: Implications for Spinal Muscular Atrophy

Symmetrical dimethylation of arginine residues in spliceosomal Sm protein B/B′ and the Sm-like protein LSm4, and their interaction with the SMN protein

Crystal Structure of the Spliceosomal 15.5kD Protein Bound to a U4 snRNA Fragment

A doughnut-shaped heteromer of human Sm-like proteins binds to the 3′-end of U6 snRNA, thereby facilitating U4/U6 duplex formation in vitro

The Sm Domain Is an Ancient RNA-Binding Motif with Oligo(U) Specificity

Spliceosome structure and function

The C-terminal RG Dipeptide Repeats of the Spliceosomal Sm Proteins D1 and D3 Contain Symmetrical Dimethylarginines, Which Form a Major B-cell Epitope for Anti-Sm Autoantibodies

Crystal Structures of Two Sm Protein Complexes and Their Implications for the Assembly of the Spliceosomal snRNPs

Mex67p, a novel factor for nuclear mRNA export, binds to both poly(A)+ RNA and nuclear pores

The snRNP core assembly pathway: identification of stable core protein heteromeric complexes and an snRNP subcore particle in vitro

The Spliceosome: Design Principles of a Dynamic RNP Machine

Sm protein-Sm site RNA interactions within the inner ring of the spliceosomal snRNP core structure

Protein functions in pre-mRNA splicing

Functional interaction of a novel 15.5kD [U4/U6.U5] tri-snRNP protein with the 5' stem-loop of U4 snRNA

Identification of Both Shared and Distinct Proteins in the Major and Minor Spliceosomes

High Intranuclear Mobility and Dynamic Clustering of the Splicing Factor U1 snRNP Observed by Single Particle Tracking

Cbf5p, a potential pseudouridine synthase, and Nhp2p, a putative RNA-binding protein, are present together with Gar1p in all H BOX/ACA-motif snoRNPs and constitute a common bipartite structure

Identification by mass spectrometry and functional analysis of novel proteins of the yeast [U4/U6.U5] tri-snRNP

Spliceosomal U snRNP Core Assembly: Sm Proteins Assemble onto an Sm Site RNA Nonanucleotide in a Specific and Thermodynamically Stable Manner

An evolutionarily conserved U5 snRNP-specific protein is a GTP-binding factor closely related to the ribosomal translocase EF-2

Single-Stranded Antisense siRNAs Guide Target RNA Cleavage in RNAi

Identification of the proteins of the yeast U1 small nuclear ribonucleoprotein complex by mass spectrometry

A general approach for identification of RNA-protein cross-linking sites within native human spliceosomal small nuclear ribonucleoproteins (snRNPs). Analysis of RNA-protein contacts in native U1 and U4/U6.U5 snRNPs

An essential signaling role for the m3G cap in the transport of U1 snRNP to the nucleus

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