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Structure of the insecticidal bacterial δ-endotoxin Cry3Bb1 of Bacillus thuringiensis

Acta crystallographica. Section D, Biological crystallography., 2001-08, Vol.57 (8), p.1101-1109

2001

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Methotrexate-resistant variants of human dihydrofolate reductase. Effects of Phe31 substitutions

The Journal of biological chemistry, 1994-04, Vol.269 (13), p.9547-9555

1994

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Structure-Based Design and Synthesis of Lipophilic 2,4-Diamino-6-Substituted Quinazolines and Their Evaluation as Inhibitors of Dihydrofolate Reductases and Potential Antitumor Agents

Journal of medicinal chemistry, 1998-08, Vol.41 (18), p.3426-3434

1998

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Structural aspects of inotropic bipyridine binding. Crystal structure determination to 1.9 A of the human serum transthyretin-milrinone complex

The Journal of biological chemistry, 1993-03, Vol.268 (9), p.6202-6206

1993

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Selective Pneumocystis carinii Dihydrofolate Reductase Inhibitors: Design, Synthesis, and Biological Evaluation of New 2,4-Diamino-5-substituted-furo[2,3-d]pyrimidines

Journal of medicinal chemistry, 1998-04, Vol.41 (8), p.1263-1271

1998

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Structure of rat transthyretin (rTTR) complex with thyroxine at 2.5 Å resolution: first non-biased insight into thyroxine binding reveals different hormone orientation in two binding sites

Acta crystallographica. Section D, Biological crystallography., 2001-08, Vol.57 (8), p.1061-1070

2001

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Structures of Human Transthyretin Complexed with Thyroxine at 2.0 Å Resolution and 3',5'-Dinitro-N-acetyl-l-thyronine at 2.2 Å Resolution

Acta crystallographica. Section D, Biological crystallography., 1996-07, Vol.52 (4), p.758-765

1996

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Lessons from high-throughput protein crystallization screening: 10 years of practical experience

Expert opinion on drug discovery, 2011-05, Vol.6 (5), p.465-480

2011

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The Rate of Water Equilibration in Vapor-Diffusion Crystallizations: Dependence on the Distance from the Droplet to the Reservoir

Acta crystallographica. Section D, Biological crystallography., 1996-11, Vol.52 (6), p.1098-1106

1996

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Crystal structure determination at 2.3 A of recombinant human dihydrofolate reductase ternary complex with NADPH and methotrexate-gamma-tetrazole

Anti-cancer drug design, 1992-12, Vol.7 (6), p.483

1992

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Intelligent decision support for protein crystal growth

IBM systems journal, 2001-01, Vol.40 (2), p.394-409

2001

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Crystal structure determination at 2.3-A resolution of human transthyretin-3',5'-dibromo-2',4,4',6-tetrahydroxyaurone complex

Proceedings of the National Academy of Sciences - PNAS, 1992-07, Vol.89 (14), p.6644-6648

1992

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Macromolecular crystallization in a high throughput laboratory—the search phase

Journal of crystal growth, 2001-11, Vol.232 (1), p.591-595

2001

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Comparison of ternary complexes of Pneumocystis carinii and wild-type human dihydrofolate reductase with coenzyme NADPH and a novel classical antitumor furo[2,3-d]pyrimidine antifolate

Acta crystallographica. Section D, Biological crystallography., 1997-11, Vol.53 (Pt 6), p.638-649

1997

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Comparison of ternary crystal complexes of F31 variants of human dihydrofolate reductase with NADPH and a classical antitumor furopyrimidine

Anti-cancer drug design, 1998-06, Vol.13 (4), p.307

1998

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Ligand-Induced Conformational Changes in the Crystal Structures of Pneumocystis carinii Dihydrofolate Reductase Complexes with Folate and NADP

Biochemistry (Easton), 1999-04, Vol.38 (14), p.4303-4312

1999

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HANGMAN: a macromolecular hanging-drop vapor-diffusion technique

Journal of applied crystallography, 1992-04, Vol.25 (2), p.324-325

1992

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Chaperone salts, polyethylene glycol and rates of equilibration in vapor-diffusion crystallization

Acta crystallographica. Section D, Biological crystallography., 1995-09, Vol.51 (5), p.780-785

1995

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Purification and crystallization of insecticidal δ-endotoxin CryIIIB2 from Bacillus thuringiensis

Proteins, structure, function, and bioinformatics, 1992-10, Vol.14 (2), p.324-324

1992

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Comparison of Two Independent Crystal Structures of Human Dihydrofolate Reductase Ternary Complexes Reduced with Nicotinamide Adenine Dinucleotide Phosphate and the Very Tight-Binding Inhibitor PT523

Biochemistry (Easton), 1997-11, Vol.36 (45), p.13897-13903

1997

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Purification and crystallization of Lactobacillus casei folylpolyglutamate synthetase expressed in Escherichia coli

Journal of molecular biology, 1992-04, Vol.224 (4), p.1179-1180

1992

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Methotrexate-resistant variants of human dihydrofolate reductase with substitutions of leucine 22. Kinetics, crystallography, and potential as selectable markers

The Journal of biological chemistry, 1995-03, Vol.270 (10), p.5057-5064

1995

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Rate of water equilibration in vapor-diffusion crystallization: dependence on the residual pressure of air in the vapor space

Acta crystallographica. Section D, Biological crystallography., 1995-09, Vol.51 (5), p.786-791

1995

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Kinetic aspects of macromolecular crystallization

Methods in enzymology, 1997, Vol.276, p.110

1997

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A method to produce microseed stock for use in the crystallization of biological macromolecules

Acta crystallographica. Section D, Biological crystallography., 1999-05, Vol.55 (5), p.988-993

1999

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Structure of the insecticidal bacterial δ-endotoxin Cry3Bb1 of Bacillus thuringiensis

Methotrexate-resistant variants of human dihydrofolate reductase. Effects of Phe31 substitutions

Structure-Based Design and Synthesis of Lipophilic 2,4-Diamino-6-Substituted Quinazolines and Their Evaluation as Inhibitors of Dihydrofolate Reductases and Potential Antitumor Agents

Structural aspects of inotropic bipyridine binding. Crystal structure determination to 1.9 A of the human serum transthyretin-milrinone complex

Selective Pneumocystis carinii Dihydrofolate Reductase Inhibitors: Design, Synthesis, and Biological Evaluation of New 2,4-Diamino-5-substituted-furo[2,3-d]pyrimidines

Structure of rat transthyretin (rTTR) complex with thyroxine at 2.5 Å resolution: first non-biased insight into thyroxine binding reveals different hormone orientation in two binding sites

Structures of Human Transthyretin Complexed with Thyroxine at 2.0 Å Resolution and 3',5'-Dinitro-N-acetyl-l-thyronine at 2.2 Å Resolution

Lessons from high-throughput protein crystallization screening: 10 years of practical experience

The Rate of Water Equilibration in Vapor-Diffusion Crystallizations: Dependence on the Distance from the Droplet to the Reservoir

Crystal structure determination at 2.3 A of recombinant human dihydrofolate reductase ternary complex with NADPH and methotrexate-gamma-tetrazole

Intelligent decision support for protein crystal growth

Crystal structure determination at 2.3-A resolution of human transthyretin-3',5'-dibromo-2',4,4',6-tetrahydroxyaurone complex

Macromolecular crystallization in a high throughput laboratory—the search phase

Comparison of ternary complexes of Pneumocystis carinii and wild-type human dihydrofolate reductase with coenzyme NADPH and a novel classical antitumor furo[2,3-d]pyrimidine antifolate

Comparison of ternary crystal complexes of F31 variants of human dihydrofolate reductase with NADPH and a classical antitumor furopyrimidine

Ligand-Induced Conformational Changes in the Crystal Structures of Pneumocystis carinii Dihydrofolate Reductase Complexes with Folate and NADP

HANGMAN: a macromolecular hanging-drop vapor-diffusion technique

Chaperone salts, polyethylene glycol and rates of equilibration in vapor-diffusion crystallization

Purification and crystallization of insecticidal δ-endotoxin CryIIIB2 from Bacillus thuringiensis

Comparison of Two Independent Crystal Structures of Human Dihydrofolate Reductase Ternary Complexes Reduced with Nicotinamide Adenine Dinucleotide Phosphate and the Very Tight-Binding Inhibitor PT523

Purification and crystallization of Lactobacillus casei folylpolyglutamate synthetase expressed in Escherichia coli

Methotrexate-resistant variants of human dihydrofolate reductase with substitutions of leucine 22. Kinetics, crystallography, and potential as selectable markers

Rate of water equilibration in vapor-diffusion crystallization: dependence on the residual pressure of air in the vapor space

Kinetic aspects of macromolecular crystallization

A method to produce microseed stock for use in the crystallization of biological macromolecules

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