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Suppression of Emergence of Resistance in Pathogenic Bacteria: Keeping Our Powder Dry, Part 1

Antimicrobial agents and chemotherapy, 2016-03, Vol.60 (3), p.1183-1193

2016

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Optimization of Aminoglycoside Therapy

Antimicrobial Agents and Chemotherapy, 2011-06, Vol.55 (6), p.2528-2531

2011

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Pharmacokinetics-Pharmacodynamics of Antimicrobial Therapy: It's Not Just for Mice Anymore

Clinical infectious diseases, 2007-01, Vol.44 (1), p.79-86

2007

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Suppression of Emergence of Resistance in Pathogenic Bacteria: Keeping Our Powder Dry, Part 2

Antimicrobial agents and chemotherapy, 2016-03, Vol.60 (3), p.1194-1201

2016

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Impact of Granulocytes on the Antimicrobial Effect of Tedizolid in a Mouse Thigh Infection Model

Antimicrobial Agents and Chemotherapy, 2011-11, Vol.55 (11), p.5300-5305

2011

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Pharmacodynamic Evaluation of Zoliflodacin Treatment of Neisseria gonorrhoeae Strains With Amino Acid Substitutions in the Zoliflodacin Target GyrB Using a Dynamic Hollow Fiber Infection Model

Frontiers in pharmacology, 2022-04, Vol.13, p.874176

2022

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In Vivo Pharmacodynamics of Torezolid Phosphate (TR-701), a New Oxazolidinone Antibiotic, against Methicillin-Susceptible and Methicillin-Resistant Staphylococcus aureus Strains in a Mouse Thigh Infection Model

Antimicrobial Agents and Chemotherapy, 2011-07, Vol.55 (7), p.3453-3460

2011

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Analysis of combination drug therapy to develop regimens with shortened duration of treatment for tuberculosis

PloS one, 2014-07, Vol.9 (7), p.e101311

2014

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Concentration-Dependent Mycobacterium tuberculosis Killing and Prevention of Resistance by Rifampin

Antimicrobial Agents and Chemotherapy, 2007-11, Vol.51 (11), p.3781-3788

2007

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Natural history of Acinetobacter baumannii infection in mice

PloS one, 2019-07, Vol.14 (7), p.e0219824-e0219824

2019

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Back to the Future: Using Aminoglycosides Again and How to Dose Them Optimally

Clinical infectious diseases, 2007-09, Vol.45 (6), p.753-760

2007

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Treatment of Invasive Aspergillosis with Posaconazole in Patients Who Are Refractory to or Intolerant of Conventional Therapy: An Externally Controlled Trial

Clinical infectious diseases, 2007-01, Vol.44 (1), p.2-12

2007

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Pharmacodynamic Evaluation of Dosing, Bacterial Kill, and Resistance Suppression for Zoliflodacin Against Neisseria gonorrhoeae in a Dynamic Hollow Fiber Infection Model

Frontiers in pharmacology, 2021-05, Vol.12, p.682135

2021

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Pharmacodynamic evaluation of lefamulin in the treatment of gonorrhea using a hollow fiber infection model simulating Neisseria gonorrhoeae infections

Frontiers in pharmacology, 2022-11, Vol.13, p.1035841-1035841

2022

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Impact of Meropenem in Combination with Tobramycin in a Murine Model of Pseudomonas aeruginosa Pneumonia

Antimicrobial Agents and Chemotherapy, 2013-06, Vol.57 (6), p.2788-2792

2013

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Pharmacodynamics of zoliflodacin plus doxycycline combination therapy against Neisseria gonorrhoeae in a gonococcal hollow-fiber infection model

Frontiers in pharmacology, 2023, Vol.14, p.1291885-1291885

2023

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Pharmacodynamics of β-Lactamase Inhibition by NXL104 in Combination with Ceftaroline: Examining Organisms with Multiple Types of β-Lactamases

Antimicrobial Agents and Chemotherapy, 2012-01, Vol.56 (1), p.258-270

2012

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Preclinical Evaluations To Identify Optimal Linezolid Regimens for Tuberculosis Therapy

mBio, 2015-11, Vol.6 (6), p.e01741-e01715

2015

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Impact of Burden on Granulocyte Clearance of Bacteria in a Mouse Thigh Infection Model

Antimicrobial Agents and Chemotherapy, 2010-10, Vol.54 (10), p.4368-4372

2010

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Isoniazid Bactericidal Activity and Resistance Emergence: Integrating Pharmacodynamics and Pharmacogenomics To Predict Efficacy in Different Ethnic Populations

Antimicrobial Agents and Chemotherapy, 2007-07, Vol.51 (7), p.2329-2336

2007

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The Relationship between Quinolone Exposures and Resistance Amplification Is Characterized by an Inverted U: a New Paradigm for Optimizing Pharmacodynamics To Counterselect Resistance

Antimicrobial Agents and Chemotherapy, 2007-02, Vol.51 (2), p.744-747

2007

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Pharmacodynamics of Caspofungin in a Murine Model of Systemic Candidiasis: Importance of Persistence of Caspofungin in Tissues to Understanding Drug Activity

Antimicrobial Agents and Chemotherapy, 2005-12, Vol.49 (12), p.5058-5068

2005

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Resistance Emergence Mechanism and Mechanism of Resistance Suppression by Tobramycin for Cefepime for Pseudomonas aeruginosa

Antimicrobial Agents and Chemotherapy, 2012-01, Vol.56 (1), p.231-242

2012

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Once-Weekly Micafungin Therapy Is as Effective as Daily Therapy for Disseminated Candidiasis in Mice with Persistent Neutropenia

Antimicrobial Agents and Chemotherapy, 2007-03, Vol.51 (3), p.968-974

2007

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The Combination of Meropenem and Levofloxacin Is Synergistic with Respect to both Pseudomonas aeruginosa Kill Rate and Resistance Suppression

Antimicrobial Agents and Chemotherapy, 2010-06, Vol.54 (6), p.2646-2654

2010

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Suppression of Emergence of Resistance in Pathogenic Bacteria: Keeping Our Powder Dry, Part 1

Optimization of Aminoglycoside Therapy

Pharmacokinetics-Pharmacodynamics of Antimicrobial Therapy: It's Not Just for Mice Anymore

Suppression of Emergence of Resistance in Pathogenic Bacteria: Keeping Our Powder Dry, Part 2

Impact of Granulocytes on the Antimicrobial Effect of Tedizolid in a Mouse Thigh Infection Model

Pharmacodynamic Evaluation of Zoliflodacin Treatment of Neisseria gonorrhoeae Strains With Amino Acid Substitutions in the Zoliflodacin Target GyrB Using a Dynamic Hollow Fiber Infection Model

In Vivo Pharmacodynamics of Torezolid Phosphate (TR-701), a New Oxazolidinone Antibiotic, against Methicillin-Susceptible and Methicillin-Resistant Staphylococcus aureus Strains in a Mouse Thigh Infection Model

Analysis of combination drug therapy to develop regimens with shortened duration of treatment for tuberculosis

Concentration-Dependent Mycobacterium tuberculosis Killing and Prevention of Resistance by Rifampin

Natural history of Acinetobacter baumannii infection in mice

Back to the Future: Using Aminoglycosides Again and How to Dose Them Optimally

Treatment of Invasive Aspergillosis with Posaconazole in Patients Who Are Refractory to or Intolerant of Conventional Therapy: An Externally Controlled Trial

Pharmacodynamic Evaluation of Dosing, Bacterial Kill, and Resistance Suppression for Zoliflodacin Against Neisseria gonorrhoeae in a Dynamic Hollow Fiber Infection Model

Pharmacodynamic evaluation of lefamulin in the treatment of gonorrhea using a hollow fiber infection model simulating Neisseria gonorrhoeae infections

Impact of Meropenem in Combination with Tobramycin in a Murine Model of Pseudomonas aeruginosa Pneumonia

Pharmacodynamics of zoliflodacin plus doxycycline combination therapy against Neisseria gonorrhoeae in a gonococcal hollow-fiber infection model

Pharmacodynamics of β-Lactamase Inhibition by NXL104 in Combination with Ceftaroline: Examining Organisms with Multiple Types of β-Lactamases

Preclinical Evaluations To Identify Optimal Linezolid Regimens for Tuberculosis Therapy

Impact of Burden on Granulocyte Clearance of Bacteria in a Mouse Thigh Infection Model

Isoniazid Bactericidal Activity and Resistance Emergence: Integrating Pharmacodynamics and Pharmacogenomics To Predict Efficacy in Different Ethnic Populations

The Relationship between Quinolone Exposures and Resistance Amplification Is Characterized by an Inverted U: a New Paradigm for Optimizing Pharmacodynamics To Counterselect Resistance

Pharmacodynamics of Caspofungin in a Murine Model of Systemic Candidiasis: Importance of Persistence of Caspofungin in Tissues to Understanding Drug Activity

Resistance Emergence Mechanism and Mechanism of Resistance Suppression by Tobramycin for Cefepime for Pseudomonas aeruginosa

Once-Weekly Micafungin Therapy Is as Effective as Daily Therapy for Disseminated Candidiasis in Mice with Persistent Neutropenia

The Combination of Meropenem and Levofloxacin Is Synergistic with Respect to both Pseudomonas aeruginosa Kill Rate and Resistance Suppression

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