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Mechanisms of transcription factor deregulation in lymphoid cell transformation

Oncogene, 2007-10, Vol.26 (47), p.6838-6849

2007

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KPT-8602, a second-generation inhibitor of XPO1-mediated nuclear export, is well tolerated and highly active against AML blasts and leukemia-initiating cells

Leukemia, 2017-01, Vol.31 (1), p.143-150

2017

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Augmented expression of MYC and/or MYCN protein defines highly aggressive MYC-driven neuroblastoma: a Children's Oncology Group study

British journal of cancer, 2015-06, Vol.113 (1), p.57-63

2015

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Evidence for an Age Cutoff Greater Than 365 Days for Neuroblastoma Risk Group Stratification in the Children's Oncology Group

Journal of clinical oncology, 2005-09, Vol.23 (27), p.6459-6465

2005

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The TCA cycle transferase DLST is important for MYC-mediated leukemogenesis

Leukemia, 2016-06, Vol.30 (6), p.1365-1374

2016

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Fusion of NUP214 to ABL1 on amplified episomes in T-cell acute lymphoblastic leukemia

Nature genetics, 2004-10, Vol.36 (10), p.1084-1089

2004

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Notch signaling expands a pre-malignant pool of T-cell acute lymphoblastic leukemia clones without affecting leukemia-propagating cell frequency

Leukemia, 2012-09, Vol.26 (9), p.2069-2078

2012

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Oncogenic Transcription Factors in the Human Acute Leukemias

Science (American Association for the Advancement of Science), 1997-11, Vol.278 (5340), p.1059-1064

Look, A. Thomas

1997

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Activity of a selective inhibitor of nuclear export, selinexor (KPT-330), against AML-initiating cells engrafted into immunosuppressed NSG mice

Leukemia, 2016-01, Vol.30 (1), p.190-199

2016

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Epigenetic therapy restores normal hematopoiesis in a zebrafish model of NUP98-HOXA9-induced myeloid disease

Leukemia, 2015-10, Vol.29 (10), p.2086-2097

2015

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Zebrafish microRNA-126 determines hematopoietic cell fate through c-Myb

Leukemia, 2011-03, Vol.25 (3), p.506-514

2011

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NOTCH1-induced T-cell leukemia in transgenic zebrafish

Leukemia, 2007-03, Vol.21 (3), p.462-471

2007

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Accurate detection of uniparental disomy and microdeletions by SNP array analysis in myelodysplastic syndromes with normal cytogenetics

Leukemia, 2009-09, Vol.23 (9), p.1605-1613

2009

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Co-injection strategies to modify radiation sensitivity and tumor initiation in transgenic Zebrafish

Oncogene, 2008-07, Vol.27 (30), p.4242-4248

2008

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Shared acquired genomic changes in zebrafish and human T-ALL

Oncogene, 2011-10, Vol.30 (41), p.4289-4296

2011

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BIM and other BCL-2 family proteins exhibit cross-species conservation of function between zebrafish and mammals

Cell death and differentiation, 2008-06, Vol.15 (6), p.1063-1072

2008

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Activating mutations in NOTCH1 in acute myeloid leukemia and lineage switch leukemias

Leukemia, 2006-11, Vol.20 (11), p.1963-1966

2006

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Biological properties of ligand-dependent activation of the MET receptor kinase in acute myeloid leukemia

Leukemia, 2015-05, Vol.29 (5), p.1218-1221

2015

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Overexpression of PDGFRA cooperates with loss of NF1 and p53 to accelerate the molecular pathogenesis of malignant peripheral nerve sheath tumors

Oncogene, 2017-02, Vol.36 (8), p.1058-1068

2017

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A new recurrent 9q34 duplication in pediatric T-cell acute lymphoblastic leukemia

Leukemia, 2006-07, Vol.20 (7), p.1245-1253

2006

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Antileukemic activity of nuclear export inhibitors that spare normal hematopoietic cells

Leukemia, 2013-01, Vol.27 (1), p.66-74

2013

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Downregulation of Bim, a Proapoptotic Relative of Bcl-2, Is a Pivotal Step in Cytokine-Initiated Survival Signaling in Murine Hematopoietic Progenitors

Molecular and Cellular Biology, 2001-02, Vol.21 (3), p.854-864

2001

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Specific induction of CD33 expression by E2A-HLF: the first evidence for aberrant myeloid antigen expression in ALL by a fusion transcription factor

Leukemia, 2010-04, Vol.24 (4), p.865-869

2010

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APOBEC signature mutation generates an oncogenic enhancer that drives LMO1 expression in T-ALL

Leukemia, 2017-10, Vol.31 (10), p.2057-2064

2017

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Significance of commonly used prognostic factors differs for children with T cell acute lymphocytic leukemia (ALL), as compared to those with B-precursor ALL. A Pediatric Oncology Group (POG) study

Leukemia, 1999-11, Vol.13 (11), p.1696-1707

1999

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Mechanisms of transcription factor deregulation in lymphoid cell transformation

KPT-8602, a second-generation inhibitor of XPO1-mediated nuclear export, is well tolerated and highly active against AML blasts and leukemia-initiating cells

Augmented expression of MYC and/or MYCN protein defines highly aggressive MYC-driven neuroblastoma: a Children's Oncology Group study

Evidence for an Age Cutoff Greater Than 365 Days for Neuroblastoma Risk Group Stratification in the Children's Oncology Group

The TCA cycle transferase DLST is important for MYC-mediated leukemogenesis

Fusion of NUP214 to ABL1 on amplified episomes in T-cell acute lymphoblastic leukemia

Notch signaling expands a pre-malignant pool of T-cell acute lymphoblastic leukemia clones without affecting leukemia-propagating cell frequency

Oncogenic Transcription Factors in the Human Acute Leukemias

Activity of a selective inhibitor of nuclear export, selinexor (KPT-330), against AML-initiating cells engrafted into immunosuppressed NSG mice

Epigenetic therapy restores normal hematopoiesis in a zebrafish model of NUP98-HOXA9-induced myeloid disease

Zebrafish microRNA-126 determines hematopoietic cell fate through c-Myb

NOTCH1-induced T-cell leukemia in transgenic zebrafish

Accurate detection of uniparental disomy and microdeletions by SNP array analysis in myelodysplastic syndromes with normal cytogenetics

Co-injection strategies to modify radiation sensitivity and tumor initiation in transgenic Zebrafish

Shared acquired genomic changes in zebrafish and human T-ALL

BIM and other BCL-2 family proteins exhibit cross-species conservation of function between zebrafish and mammals

Activating mutations in NOTCH1 in acute myeloid leukemia and lineage switch leukemias

Biological properties of ligand-dependent activation of the MET receptor kinase in acute myeloid leukemia

Overexpression of PDGFRA cooperates with loss of NF1 and p53 to accelerate the molecular pathogenesis of malignant peripheral nerve sheath tumors

A new recurrent 9q34 duplication in pediatric T-cell acute lymphoblastic leukemia

Antileukemic activity of nuclear export inhibitors that spare normal hematopoietic cells

Downregulation of Bim, a Proapoptotic Relative of Bcl-2, Is a Pivotal Step in Cytokine-Initiated Survival Signaling in Murine Hematopoietic Progenitors

Specific induction of CD33 expression by E2A-HLF: the first evidence for aberrant myeloid antigen expression in ALL by a fusion transcription factor

APOBEC signature mutation generates an oncogenic enhancer that drives LMO1 expression in T-ALL

Significance of commonly used prognostic factors differs for children with T cell acute lymphocytic leukemia (ALL), as compared to those with B-precursor ALL. A Pediatric Oncology Group (POG) study

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