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Pancreatic β Cell Dedifferentiation as a Mechanism of Diabetic β Cell Failure

Cell, 2012-09, Vol.150 (6), p.1223-1234

2012

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Hormonal Regulation of Hepatic Glucose Production in Health and Disease

Cell metabolism, 2011-07, Vol.14 (1), p.9-19

2011

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Butyrate and propionate protect against diet-induced obesity and regulate gut hormones via free fatty acid receptor 3-independent mechanisms

PloS one, 2012-04, Vol.7 (4), p.e35240-e35240

2012

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GPR142 Agonists Stimulate Glucose-Dependent Insulin Secretion via Gq-Dependent Signaling

PloS one, 2016-04, Vol.11 (4), p.e0154452-e0154452

2016

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GPR142 Controls Tryptophan-Induced Insulin and Incretin Hormone Secretion to Improve Glucose Metabolism

PloS one, 2016-06, Vol.11 (6), p.e0157298-e0157298

2016

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Proatherogenic Abnormalities of Lipid Metabolism in SirT1 Transgenic Mice Are Mediated through Creb Deacetylation

Cell metabolism, 2011-12, Vol.14 (6), p.758-767

2011

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Connexin 43 Mediates White Adipose Tissue Beiging by Facilitating the Propagation of Sympathetic Neuronal Signals

Cell metabolism, 2016-09, Vol.24 (3), p.420-433

2016

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A FOXO1-dependent transcription network is a targetable vulnerability of mantle cell lymphomas

The Journal of clinical investigation, 2022-12, Vol.132 (24), p.1-16

2022

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Divergent Regulation of Energy Expenditure and Hepatic Glucose Production by Insulin Receptor in Agouti-Related Protein and POMC Neurons

Diabetes (New York, N.Y.), 2010-02, Vol.59 (2), p.337-346

2010

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Diabetes treatment by conversion of gut epithelial cells to insulin‐producing cells

Journal of diabetes investigation, 2024-07, Vol.15 (7), p.797-804

2024

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FOXO1 inhibition synergizes with FGF21 to normalize glucose control in diabetic mice

Molecular metabolism (Germany), 2021-07, Vol.49, p.101187-101187, Article 101187

2021

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Increased Atherosclerosis and Endothelial Dysfunction in Mice Bearing Constitutively Deacetylated Alleles of Foxo1 Gene

The Journal of biological chemistry, 2012-04, Vol.287 (17), p.13944-13951

2012

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GPR142 prompts glucagon-like Peptide-1 release from islets to improve β cell function

Molecular metabolism (Germany), 2018-05, Vol.11, p.205-211

2018

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Reconstitution of Insulin Action in Muscle, White Adipose Tissue, and Brain of Insulin Receptor Knock-out Mice Fails to Rescue Diabetes

The Journal of biological chemistry, 2011-03, Vol.286 (11), p.9797-9804

2011

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Chemical induction of gut β-like-cells by combined FoxO1/Notch inhibition as a glucose-lowering treatment for diabetes

Molecular metabolism (Germany), 2022-12, Vol.66, p.101624-101624, Article 101624

2022

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InsR/FoxO1 signaling curtails hypothalamic POMC neuron number

PloS one, 2012-02, Vol.7 (2), p.e31487-e31487

2012

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Identification and characterization of sebaceous gland atrophy-sparing DGAT1 inhibitors

PloS one, 2014-02, Vol.9 (2), p.e88908

2014

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Adiponectin Resistance Exacerbates Insulin Resistance in Insulin Receptor Transgenic/Knockout Mice

Diabetes (New York, N.Y.), 2007-08, Vol.56 (8), p.1969-1976

2007

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Normal Bone Density Obtained in the Absence of Insulin Receptor Expression in Bone

Endocrinology (Philadelphia), 2006-12, Vol.147 (12), p.5760-5767

2006

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Diacylglycerol acyltransferase-1 (DGAT1) inhibition perturbs postprandial gut hormone release

PloS one, 2013-01, Vol.8 (1), p.e54480-e54480

2013

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Wingless eliminates ommatidia from the edge of the developing eye through activation of apoptosis

Development (Cambridge), 2004-05, Vol.131 (10), p.2409-2418

2004

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Hepatic GALE Regulates Whole-Body Glucose Homeostasis by Modulating Tff3 Expression

Diabetes (New York, N.Y.), 2017-11, Vol.66 (11), p.2789-2799

2017

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The obesity susceptibility gene Cpe links FoxO1 signaling in hypothalamic pro-opiomelanocortin neurons with regulation of food intake

Nature medicine, 2009-10, Vol.15 (10), p.1195-1201

2009

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Discovery of LY3325656: A GPR142 agonist suitable for clinical testing in human

Bioorganic & medicinal chemistry letters, 2020-03, Vol.30 (5), p.126857, Article 126857

2020

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20-OR: GPR142 Agonists Increase Glucose-Dependent Insulin Secretion and Differentially Regulate Hormone Secretion in Preclinical and Phase 1 Studies

Diabetes (New York, N.Y.), 2019-06, Vol.68 (Supplement_1)

2019

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Pancreatic β Cell Dedifferentiation as a Mechanism of Diabetic β Cell Failure

Hormonal Regulation of Hepatic Glucose Production in Health and Disease

Butyrate and propionate protect against diet-induced obesity and regulate gut hormones via free fatty acid receptor 3-independent mechanisms

GPR142 Agonists Stimulate Glucose-Dependent Insulin Secretion via Gq-Dependent Signaling

GPR142 Controls Tryptophan-Induced Insulin and Incretin Hormone Secretion to Improve Glucose Metabolism

Proatherogenic Abnormalities of Lipid Metabolism in SirT1 Transgenic Mice Are Mediated through Creb Deacetylation

Connexin 43 Mediates White Adipose Tissue Beiging by Facilitating the Propagation of Sympathetic Neuronal Signals

A FOXO1-dependent transcription network is a targetable vulnerability of mantle cell lymphomas

Divergent Regulation of Energy Expenditure and Hepatic Glucose Production by Insulin Receptor in Agouti-Related Protein and POMC Neurons

Diabetes treatment by conversion of gut epithelial cells to insulin‐producing cells

FOXO1 inhibition synergizes with FGF21 to normalize glucose control in diabetic mice

Increased Atherosclerosis and Endothelial Dysfunction in Mice Bearing Constitutively Deacetylated Alleles of Foxo1 Gene

GPR142 prompts glucagon-like Peptide-1 release from islets to improve β cell function

Reconstitution of Insulin Action in Muscle, White Adipose Tissue, and Brain of Insulin Receptor Knock-out Mice Fails to Rescue Diabetes

Chemical induction of gut β-like-cells by combined FoxO1/Notch inhibition as a glucose-lowering treatment for diabetes

InsR/FoxO1 signaling curtails hypothalamic POMC neuron number

Identification and characterization of sebaceous gland atrophy-sparing DGAT1 inhibitors

Adiponectin Resistance Exacerbates Insulin Resistance in Insulin Receptor Transgenic/Knockout Mice

Normal Bone Density Obtained in the Absence of Insulin Receptor Expression in Bone

Diacylglycerol acyltransferase-1 (DGAT1) inhibition perturbs postprandial gut hormone release

Wingless eliminates ommatidia from the edge of the developing eye through activation of apoptosis

Hepatic GALE Regulates Whole-Body Glucose Homeostasis by Modulating Tff3 Expression

The obesity susceptibility gene Cpe links FoxO1 signaling in hypothalamic pro-opiomelanocortin neurons with regulation of food intake

Discovery of LY3325656: A GPR142 agonist suitable for clinical testing in human

20-OR: GPR142 Agonists Increase Glucose-Dependent Insulin Secretion and Differentially Regulate Hormone Secretion in Preclinical and Phase 1 Studies

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